製品の概要

  • 製品名Anti-HSD3a antibody
    HSD3a 一次抗体 製品一覧
  • 製品の詳細
    Goat polyclonal to HSD3a
  • 特異性This antibody may cross-react with AKR1C1.
  • アプリケーション適用あり: WB, ELISA, IHC-Pmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Cynomolgus Monkey, Macaque Monkey
  • 免疫原

    Synthetic peptide:

    C-DPKYQRVELNDGH

    , corresponding to N terminal amino acids 2-14 of Human HSD3a

  • ポジティブ・コントロール
    • Human Liver lysate.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab50415 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 0.1 - 0.3 µg/ml. Detects a band of approximately 35 kDa (predicted molecular weight: 37 kDa).
ELISA Use at an assay dependent dilution.
IHC-P Use a concentration of 2 - 4 µg/ml.

ターゲット情報

  • 機能Catalyzes the transformation of the potent androgen dihydrotestosterone (DHT) into the less active form, 5-alpha-androstan-3-alpha,17-beta-diol (3-alpha-diol). Also has some 20-alpha-hydroxysteroid dehydrogenase activity. The biotransformation of the pesticide chlordecone (kepone) to its corresponding alcohol leads to increased biliary excretion of the pesticide and concomitant reduction of its neurotoxicity since bile is the major excretory route.
  • 組織特異性Liver specific.
  • 配列類似性Belongs to the aldo/keto reductase family.
  • 翻訳後修飾The N-terminus is blocked.
  • 細胞内局在Cytoplasm.
  • Information by UniProt
  • 参照データベース
  • 別名
    • 3 alpha HSD1 antibody
    • 3-alpha-HSD1 antibody
    • 3-alpha-hydroxysteroid dehydrogenase type I antibody
    • AK1C4_HUMAN antibody
    • AKR1C4 antibody
    • Aldo keto reductase family 1 member C4 antibody
    • Aldo-keto reductase family 1 member C4 antibody
    • CDR antibody
    • Chlordecone reductase antibody
    • DD-4 antibody
    • DD4 antibody
    • Dihydrodiol dehydrogenase 4 antibody
    • HAKRA antibody
    see all

Anti-HSD3a antibody 画像

  • Anti-HSD3a antibody (ab50415) at 0.1 µg/ml + Human Liver lysate (35µg protein in RIPA buffer).

    Predicted band size : 37 kDa
    Observed band size : 35 kDa (why is the actual band size different from the predicted?)
  • ab50415 at 4µg/ml staining HSD3a in Human liver tissue section by Immunohistochemistry (Formalin/ PFA-fixed paraffin-embedded tissue sections). The tissue underwent antigen retrieval by steam in citrate buffer pH 6.0.

Anti-HSD3a antibody (ab50415) 使用論文

ab50415 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"