製品の概要

  • 製品名Anti-HSD17B6 antibody
    HSD17B6 一次抗体 製品一覧
  • 製品の詳細
    Mouse polyclonal to HSD17B6
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Full length human HSD17B6 protein (NP_003716.2).

  • ポジティブ・コントロール
    • Human liver tissue lysate; HSD17B6 transfected 293T cell lysate

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • バッファーPreservative: None
    Constituents: 1 x PBS, pH 7.2
  • Concentration information loading...
  • 精製度Protein A purified
  • ポリ/モノポリクローナル
  • アイソタイプIgG
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab88893 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 36 kDa.

ターゲット情報

  • 機能NAD-dependent oxidoreductase with broad substrate specificity that shows both oxidative and reductive activity (in vitro). Has 17-beta-hydroxysteroid dehydrogenase activity towards various steroids (in vitro). Converts 5-alpha-androstan-3-alpha,17-beta-diol to androsterone and estradiol to estrone (in vitro). Has 3-alpha-hydroxysteroid dehydrogenase activity towards androsterone (in vitro). Has retinol dehydrogenase activity towards all-trans-retinol (in vitro). Can convert androsterone to epi-androsterone. Androsterone is first oxidized to 5-alpha-androstane-3,17-dione and then reduced to epi-andosterone. Can act on both C-19 and C-21 3-alpha-hydroxysteroids.
  • 組織特異性Detected in liver and prostate (at protein level). Detected in adult liver, lung, brain, placenta, prostate, adrenal gland, testis, mammary gland, spleen, spinal cord and uterus. Detected in caudate nucleus, and at lower levels in amygdala, corpus callosum, hippocampus, substantia nigra and thalamus. Detected in fetal lung, liver and brain.
  • 配列類似性Belongs to the short-chain dehydrogenases/reductases (SDR) family.
  • 細胞内局在Microsome membrane. Early endosome membrane.
  • Information by UniProt
  • 参照データベース
  • 別名
    • 17-beta-HSD 6 antibody
    • 17-beta-HSD6 antibody
    • 17-beta-hydroxysteroid dehydrogenase type 6 antibody
    • 3 hydroxysteroid epimerase antibody
    • 3(alpha >beta) hydroxysteroid epimerase antibody
    • 3(alpha >beta) hydroxysteroid epimerasel antibody
    • 3-alpha->beta-HSE antibody
    • 3-alpha->beta-hydroxysteroid epimerase antibody
    • H17B6_HUMAN antibody
    • HSD17B6 antibody
    • HSE antibody
    • Hydroxysteroid (17 beta) dehydrogenase 6 antibody
    • Hydroxysteroid (17 beta) dehydrogenase 6 homolog (mouse) antibody
    • Hydroxysteroid 17 beta dehydrogenase 6 antibody
    • NAD+ dependent 3 alpha hydroxysteroid dehydrogenase 3 hydroxysteroid epimerase antibody
    • NAD+ dependent 3 alpha hydroxysteroid dehydrogenase antibody
    • Oxidative 3 alpha hydroxysteroid dehydrogenase antibody
    • Oxidative 3-alpha hydroxysteroid dehydrogenase antibody
    • Oxidoreductase antibody
    • Retinol dehydrogenase antibody
    • RODH antibody
    • SDR9C6 antibody
    • Short chain dehydrogenase/reductase family 9C, member 6 antibody
    see all

Anti-HSD17B6 antibody 画像

  • Anti-HSD17B6 antibody (ab88893) at 1 µg/ml + human liver tissue lysate at 50 µg
    Developed using the ECL technique

    Predicted band size : 36 kDa
    Observed band size : ~30 kDa (why is the actual band size different from the predicted?)
  • All lanes : Anti-HSD17B6 antibody (ab88893) at 1 µg/ml

    Lane 1 : HSD17B6 transfected 293T cell lysate
    Lane 2 : non transfected 293T cell lysate

    Lysates/proteins at 25 µg per lane.

    Developed using the ECL technique

    Predicted band size : 36 kDa
    Observed band size : 37 kDa (why is the actual band size different from the predicted?)
    Additional bands at : 25 kDa,~30 kDa. We are unsure as to the identity of these extra bands.

Anti-HSD17B6 antibody (ab88893) 使用論文

ab88893 has not yet been referenced specifically in any publications.

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