製品の概要

  • 製品名Anti-HSD17B3 antibody
    HSD17B3 一次抗体 製品一覧
  • 製品の詳細
    Mouse polyclonal to HSD17B3
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Full length human HSD17B3 protein (NP_000188.1)

  • ポジティブ・コントロール
    • HSD17B3 transfected 293T cell lysate.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab70089 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/500 - 1/1000. Detects a band of approximately 30 kDa (predicted molecular weight: 35 kDa).

ターゲット情報

  • 機能Favors the reduction of androstenedione to testosterone. Uses NADPH while the two other EDH17B enzymes use NADH.
  • 組織特異性Testis.
  • パスウェイHormone biosynthesis; testosterone biosynthesis.
  • 関連疾患Defects in HSD17B3 are the cause of male pseudohermaphrodism with gynecomastia (MPH) [MIM:264300]. These individuals have unambiguous female external genitalia at birth, but fail to menstruate at the time of expected puberty and instead virilize as evidenced by growth of the phallus. Breast development may or may not take place.
  • 配列類似性Belongs to the short-chain dehydrogenases/reductases (SDR) family. 17-beta-HSD 3 subfamily.
  • Information by UniProt
  • 参照データベース
  • 別名
    • 17 @beta HSD III antibody
    • 17 beta HSD 3 antibody
    • 17-@beta hydroxysteroid dehydrogenase III antibody
    • 17-beta-HSD 3 antibody
    • 17-beta-hydroxysteroid dehydrogenase type 3 antibody
    • DHB3_HUMAN antibody
    • EC 1.1.1.64 antibody
    • EDH17B3 antibody
    • Estradiol 17 beta dehydrogenase antibody
    • Estradiol 17 beta dehydrogenase 3 antibody
    • HSD17B3 antibody
    • Hydroxysteroid (17 beta) dehydrogenase 3 antibody
    • OTTHUMP00000021718 antibody
    • SDR12C2 antibody
    • Short chain dehydrogenase/reductase family 12C member 2 antibody
    • Testicular 17 @beta hydroxysteroid dehydrogenase III antibody
    • Testicular 17 beta hydroxysteroid dehydrogenase antibody
    • Testicular 17-beta-hydroxysteroid dehydrogenase antibody
    • Testosterone 17 beta dehydrogenase 3 antibody
    • Testosterone 17-beta-dehydrogenase 3 antibody
    see all

Anti-HSD17B3 antibody 画像

  • All lanes : Anti-HSD17B3 antibody (ab70089) at 1/500 dilution

    Lane 1 : HSD17B3 transfected 293T cell lysate
    Lane 2 : Non-transfected 293T cell lysate

    Lysates/proteins at 25 µg per lane.

    Secondary
    Goat Anti-Mouse IgG (H&L)-HRP Conjugate at 1/2500 dilution

    Predicted band size : 35 kDa
    Observed band size : 30 kDa (why is the actual band size different from the predicted?)

Anti-HSD17B3 antibody (ab70089) 使用論文

ab70089 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab70089.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"