製品の概要

  • 製品名Anti-HSD17B12 antibody
    HSD17B12 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to HSD17B12
  • アプリケーション適用あり: WB, IHC-Pmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Synthetic peptide corresponding to Human HSD17B12 (internal sequence) conjugated to Keyhole Limpet Haemocyanin (KLH).

  • ポジティブ・コントロール
    • A2058 cell line lysates, Human hepatocarcinoma tissue.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab103107 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/100 - 1/500. Predicted molecular weight: 34 kDa.
IHC-P 1/50 - 1/100. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

ターゲット情報

  • 機能Catalyzes the transformation of estrone (E1) into estradiol (E2), suggesting a central role in estrogen formation. Its strong expression in ovary and mammary gland suggest that it may constitute the major enzyme responsible for the conversion of E1 to E2 in women. Also has 3-ketoacyl-CoA reductase activity, reducing both long chain 3-ketoacyl-CoAs and long chain fatty acyl-CoAs, suggesting a role in long fatty acid elongation.
  • 組織特異性Expressed in most tissues tested. Highly expressed in the ovary and mammary. Expressed in platelets.
  • パスウェイSteroid biosynthesis; estrogen biosynthesis.
    Lipid metabolism; fatty acid biosynthesis.
  • 配列類似性Belongs to the short-chain dehydrogenases/reductases (SDR) family. 17-beta-HSD 3 subfamily.
  • ドメインThe di-lysine motif confers endoplasmic reticulum localization for type I membrane proteins.
  • 細胞内局在Endoplasmic reticulum membrane.
  • Information by UniProt
  • 参照データベース
  • 別名
    • 12,3-ketoacyl-CoA reductase,short chain antibody
    • 17 beta HSD 12 antibody
    • 17 beta hydroxysteroid dehydrogenase 12 antibody
    • 17-@beta-HSD XII antibody
    • 17-@beta-hydroxysteroid dehydrogenase XII antibody
    • 17-beta-HSD 12 antibody
    • 17-beta-hydroxysteroid dehydrogenase 12 antibody
    • 17beta HSD type 12 antibody
    • 3 ketoacyl CoA reductase antibody
    • 3-ketoacyl-CoA reductase antibody
    • DHB12_HUMAN antibody
    • Estradiol 17 beta dehydrogenase 12 antibody
    • Estradiol 17-beta-dehydrogenase 12 antibody
    • HSD17B12 antibody
    • Hydroxysteroid (17-beta) dehydrogenase 12 antibody
    • KAR antibody
    • KIK-I antibody
    • Kik1 antibody
    • SDR12C1 antibody
    • Short chain dehydrogenase/reductase family 12C member 1 antibody
    • Steroid dehydrogenase homolog antibody
    see all

Anti-HSD17B12 antibody 画像

  • Anti-HSD17B12 antibody (ab103107) at 1/100 dilution + A2058 cell line lysates at 35 µg

    Predicted band size : 34 kDa
  • ab103107 at 1/50 dilution staining HSD17B12 in Human hepatocarcinoma by Immunohistochemistry Formalin-fixed, Paraffin-embedded tissue. Detection: DAB staining

Anti-HSD17B12 antibody (ab103107) 使用論文

ab103107 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"