製品の概要

  • 製品名Anti-HSD11B2 antibody
    HSD11B2 一次抗体 製品一覧
  • 製品の詳細
    Mouse polyclonal to HSD11B2
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Full length human HSD11B2 protein (AAH64536.1).

  • ポジティブ・コントロール
    • Human colon tissue lysate and HSD11B2 transfected 293T cell lysate

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab89669 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 44 kDa.

ターゲット情報

  • 機能Catalyzes the conversion of cortisol to the inactive metabolite cortisone. Modulates intracellular glucocorticoid levels, thus protecting the nonselective mineralocorticoid receptor from occupation by glucocorticoids.
  • 組織特異性Found in placenta, kidney, pancreas, prostate, ovary, small intestine and colon.
  • 関連疾患Defects in HSD11B2 are the cause of apparent mineralocorticoid excess (AME) [MIM:218030]. AME is a potentially fatal disease characterized by severe juvenile low-renin hypertension, sodium retention, hypokalemia and low levels of aldosterone. It often leads to nephrocalcinosis.
  • 配列類似性Belongs to the short-chain dehydrogenases/reductases (SDR) family.
  • 細胞内局在Microsome. Endoplasmic reticulum.
  • Information by UniProt
  • 参照データベース
  • 別名
    • 11 beta HSD2 antibody
    • 11 beta hydroxysteroid dehydrogenase type 2 antibody
    • 11 DH2 antibody
    • 11-beta-HSD2 antibody
    • 11-beta-hydroxysteroid dehydrogenase type 2 antibody
    • 11-DH2 antibody
    • AME antibody
    • AME1 antibody
    • Corticosteroid 11 beta dehydrogenase isozyme 2 antibody
    • Corticosteroid 11-beta-dehydrogenase isozyme 2 antibody
    • DHI2_HUMAN antibody
    • HSD11B2 antibody
    • HSD11K antibody
    • HSD2 antibody
    • Hydroxysteroid 11 beta dehydrogenase 2 antibody
    • Hydroxysteroid 11 beta dehydrogenase isoenzyme 2 antibody
    • NAD dependent 11 beta hydroxysteroid dehydrogenase antibody
    • NAD-dependent 11-beta-hydroxysteroid dehydrogenase antibody
    • SDR9C3 antibody
    • Short chain dehydrogenase/reductase family 9C, member 3 antibody
    see all

Anti-HSD11B2 antibody 画像

  • Anti-HSD11B2 antibody (ab89669) at 1 µg/ml + human colon tissue lysate at 50 µg

    Predicted band size : 44 kDa
    Observed band size : 37 kDa (why is the actual band size different from the predicted?)
  • All lanes : Anti-HSD11B2 antibody (ab89669) at 1 µg/ml

    Lane 1 : HSD11B2 transfected 293T cell lysate
    Lane 2 : Non transfected 293T cell lysate

    Lysates/proteins at 25 µg per lane.


    Predicted band size : 44 kDa
    Observed band size : 41 kDa (why is the actual band size different from the predicted?)

Anti-HSD11B2 antibody (ab89669) 使用論文

ab89669 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"