Anti-Hsc82 抗体 (ab30920)
Key features and details
- Rabbit polyclonal to Hsc82
- Suitable for: WB
- Reacts with: Saccharomyces cerevisiae
- Isotype: IgG
製品の概要
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製品名
Anti-Hsc82 antibody -
製品の詳細
Rabbit polyclonal to Hsc82 -
由来種
Rabbit -
アプリケーション
適用あり: WBmore details -
種交差性
交差種: Saccharomyces cerevisiae -
免疫原
Synthetic peptide corresponding to Saccharomyces cerevisiae Hsc82 aa 650 to the C-terminus conjugated to keyhole limpet haemocyanin.
(Peptide available asab31800) -
ポジティブ・コントロール
- Saccharomyces cerevisiae Whole Cell Lysate
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
バッファー
pH: 7.40
Preservative: 0.02% Sodium azide
Constituent: PBS
Batches of this product that have a concentration < 1mg/ml may have BSA added as a stabilising agent. If you would like information about the formulation of a specific lot, please contact our scientific support team who will be happy to help. -
Concentration information loading...
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精製度
Immunogen affinity purified -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab30920の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
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WB |
Use a concentration of 1 µg/ml. Detects a band of approximately 81 kDa (predicted molecular weight: 81 kDa).
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特記事項 |
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WB
Use a concentration of 1 µg/ml. Detects a band of approximately 81 kDa (predicted molecular weight: 81 kDa). |
ターゲット情報
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関連性
The budding yeast Saccharomyces cerevisiae has two genes, HSP82 and HSC82, that encode homologues of HSP90. HSC82 is a molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved in cell cycle control. Cells overexpressing Hsc82 are hypersensitive to various stresses including high concentrations of NaCl. The phenotypes associated with the sensitivity to salt stress of Hsc82-overexpressing cells are similar to those of calcineurin-defective mutants. -
細胞内局在
Cytoplasmic and Mitochondrial -
参照データベース
- Entrez Gene: 855224 Saccharomyces cerevisiae
- SwissProt: P15108 Saccharomyces cerevisiae
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別名
- 82 kDa heat shock cognate protein antibody
- ATP-dependent molecular chaperone HSC82 antibody
- Heat shock protein Hsp90 constitutive isoform antibody
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データシートおよび資料
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SDS download
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Datasheet download
参考文献 (5)
ab30920 は 5 報の論文で使用されています。
- Gaur D et al. Ydj1 interaction at nucleotide-binding-domain of yeast Ssa1 impacts Hsp90 collaboration and client maturation. PLoS Genet 18:e1010442 (2022). PubMed: 36350833
- Reidy M & Masison DC Mutations in the Hsp90 N Domain Identify a Site that Controls Dimer Opening and Expand Human Hsp90a Function in Yeast. J Mol Biol 432:4673-4689 (2020). PubMed: 32565117
- Gaur D et al. The Yeast Hsp70 Cochaperone Ydj1 Regulates Functional Distinction of Ssa Hsp70s in the Hsp90 Chaperoning Pathway. Genetics 215:683-698 (2020). PubMed: 32299842
- Ly N & Cyert MS Calcineurin, the Ca(2+)-dependent phosphatase, regulates Rga2, a Cdc42 GTPase-activating protein, to modulate pheromone signaling. Mol Biol Cell 28:576-586 (2017). WB ; Saccharomyces cerevisiae . PubMed: 28077617
- Weir NR et al. The AAA protein Msp1 mediates clearance of excess tail-anchored proteins from the peroxisomal membrane. Elife 6:N/A (2017). WB ; Saccharomyces cerevisiae . PubMed: 28906250