The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
追加情報This antibody gave a positive result in ELISA against the immunizing peptide. Antibody detection limit dilution 1:128,000.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
機能The H2 subclass of histamine receptors mediates gastric acid secretion. Also appears to regulate gastrointestinal motility and intestinal secretion. Possible role in regulating cell growth and differentiation. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase and, through a separate G protein-dependent mechanism, the phosphoinositide/protein kinase (PKC) signaling pathway.
配列類似性Belongs to the G-protein coupled receptor 1 family.