Anti-HRG 抗体 [RM0091-9G42] (ab86451)

製品の概要

  • 製品名
    Anti-HRG antibody [RM0091-9G42]
    HRG 一次抗体 製品一覧
  • 製品の詳細
    Rat monoclonal [RM0091-9G42] to HRG
  • アプリケーション
    適用あり: WBmore details
  • 種交差性
    交差種: Mouse
  • 免疫原

    Recombinant HRG protein (Mouse)

  • 特記事項


    This antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from an immunized rat).

製品の特性

  • 製品の状態
    Liquid
  • 保存方法
    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • バッファー
    Preservative: None
    Constituents: PBS
  • Concentration information loading...
  • 精製度
    Protein A purified
  • 特記事項(精製)
    The IgG fraction of culture supernatant was purified by Protein A/G affinity chromatography and lyophilized from an 0.2 µm filtered solution.
  • 一次抗体 備考
    This antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from an immunized rat).
  • ポリ/モノ
    モノクローナル
  • クローン名
    RM0091-9G42
  • アイソタイプ
    IgG2
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab86451 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/500 - 1/1000. Predicted molecular weight: 60 kDa.

ターゲット情報

  • 関連性
    HRG (histidine-rich glycoprotein) contains two cystatin-like domains and is located in plasma and platelets. The physiological function is not yet known. It binds heme, dyes and divalent metal ions. It can inhibit rosette formation and interacts with heparin, thrombospondin, and the lysine-binding site of plasminogen. A potential prothrombotic effect of HRG is indicated by the inhibition of fibrinolysis and the reduction of inhibition of coagulation. Mutations in HRG lead to thrombophilia due to abnormal histidine-rich glycoprotein levels.
  • 細胞内局在
    Secreted
  • 参照データベース
  • 別名
    • DKFZp779H1622 antibody
    • Histidine proline rich glycoprotein antibody
    • Histidine rich glycoprotein antibody
    • HPRG antibody
    • HRGP antibody
    • Thrombophilia due to elevated HRG antibody
    see all

プロトコール

参考文献

ab86451 has not yet been referenced specifically in any publications.

レビューと Q&A

The Anti-HRG antibody [RM0091-9G42] (ab86451) has been raised against the full length recombinant mouse HRG protein. Unfortunately the specific epitope recognised by the antibody produced from this clone has not as yet been determined.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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