Anti-HPV18 E6 抗体 [BF7] (ab20192)
製品の概要
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製品名Anti-HPV18 E6 antibody [BF7]
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製品の詳細Mouse monoclonal [BF7] to HPV18 E6
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由来種Mouse
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アプリケーション適用あり: WB, RIA, ELISAmore details
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免疫原
Gel-purified HPV-18 E6-beta-galactosidase fusion protein
製品の特性
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製品の状態Liquid
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保存方法Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
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バッファーPreservative: None
Constituents: PBS -
Concentration information loading... -
ポリ/モノモノクローナル
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クローン名BF7
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ミエローマNS1
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アイソタイプIgG1
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軽鎖の種類unknown
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研究分野
関連製品
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Compatible Secondaries
アプリケーション
Our Abpromise guarantee covers the use of ab20192 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| アプリケーション | Abreviews | 特記事項 |
|---|---|---|
| WB | Use at an assay dependent dilution. Predicted molecular weight: 17 kDa. | |
| RIA | Use at an assay dependent dilution. | |
| ELISA | Use at an assay dependent dilution. |
ターゲット情報
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関連性The human papilloma virus (HPV) family of DNA tumor viruses includes HPV-16 and HPV-18, which are associated with a large proportion of cervical cancer cases. HPV early proteins E6 and E7 are the major viral oncoproteins that regulate cell proliferation through the inactivation of p53 and Rb1 tumour suppressor proteins respectively. BF7 can be used for detection of HPV in cervical smears and biopsies and analysis of E6 expression in cell transformation studies.
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別名
- E6 antibody
- Human papillomavirus type 18 E6 antibody
- Protein E6 antibody
プロトコール
参考文献
This product has been referenced in:
- Cheng Y et al. Human papillomavirus E6-regulated microRNA-20b promotes invasion in cervical cancer by targeting tissue inhibitor of metalloproteinase 2. Mol Med Rep 16:5464-5470 (2017). Read more (PubMed: 28849054) »
- Banks L et al. Identification of human papillomavirus type 18 E6 polypeptide in cells derived from human cervical carcinomas. J Gen Virol 68 ( Pt 5):1351-9 (1987). Read more (PubMed: 3033140) »
レビューと Q&A
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"