製品の概要

  • 製品名
    Anti-HPV16 E1+E4 antibody [TVG 403]
    HPV16 E1+E4 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal [TVG 403] to HPV16 E1+E4
  • アプリケーション
    適用あり: IHC-Fr, ELISA, Flow Cytmore details
  • 種交差性
    Human papilloma virus.
  • 免疫原

    Fusion protein (Human). Antigen for hybridoma production was expressed as a b-galactosidase fusion protein using the pEX expression system and was consequently cleaved to release the E1/E4 polypeptide.

  • エピトープ
    E1/E4 protein is aa 36-41 of human papilloma virus type 16.
  • 特記事項


    This antibody is of value in monitoring the progress of HPV infection from benign lesions to invasive cancer.

製品の特性

  • 製品の状態
    Liquid
  • 保存方法
    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • バッファー
    Preservative: None
    Constituents: PBS
  • Concentration information loading...
  • 精製度
    IgG fraction
  • 一次抗体 備考
    This antibody is of value in monitoring the progress of HPV infection from benign lesions to invasive cancer.
  • ポリ/モノ
    モノクローナル
  • クローン名
    TVG 403
  • ミエローマ
    NS0
  • アイソタイプ
    IgG1
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab20190 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
IHC-Fr Use at an assay dependent concentration.
ELISA Use at an assay dependent concentration.
Flow Cyt Use at an assay dependent concentration. ab170190-Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody.

ターゲット情報

  • 関連性
    HPV16 is an ATP-dependent DNA helicase required for initiation of viral DNA replication. It forms a complex with the viral E2 protein. The E1-E2 complex binds to the replication origin which contains binding sites for both proteins. HPV16, in comparison to HPV types 6 and 11, is more often associated with malignant genital cancers in humans.
  • 細胞内局在
    Nuclear
  • 別名
    • ATP dependent helicase E1 antibody
    • E1 antibody
    • E4 antibody
    • HPV16 E1 antibody
    • HPV16 E4 antibody
    • Human papillomavirus type 16 E1 antibody
    • Human papillomavirus type 16 E4 antibody
    • Replication protein antibody
    • Replication protein E1 antibody
    see all

参考文献

This product has been referenced in:
  • Doorbar J  et al. The E1E4 protein of human papillomavirus type 16 associates with a putative RNA helicase through sequences in its C terminus. J Virol 74:10081-95 (2000). Read more (PubMed: 11024137) »

See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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