製品の概要

  • 製品名
  • 製品の詳細
    Rabbit polyclonal to HPS3
  • アプリケーション
    適用あり: WB, IHC-Pmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Synthetic peptide corresponding to a region within amino acids 992-1004 (

    PYLLYCSRKKPLT

    ) of Human HPS3 (NP_115759).

  • ポジティブ・コントロール
    • 293T, A431, H1299, HeLa S3, HepG2, MOLT4 and Raji whole cell lysates; SW480 tissue

法規制情報

製品の特性

  • 製品の状態
    Liquid
  • 保存方法
    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • バッファー
    Preservative: 0.01% Thimerosal (merthiolate)
    Constituents: 10% Glycerol, 0.1M Tris, 0.1M Glycine, pH 7.0
  • Concentration information loading...
  • 精製度
    Immunogen affinity purified
  • ポリ/モノ
    ポリクローナル
  • アイソタイプ
    IgG
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab96343 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/500 - 1/3000. Predicted molecular weight: 114 kDa.
IHC-P 1/100 - 1/500.

ターゲット情報

  • 関連性
    HPS3 is involved in early stages of melanosome biogenesis and maturation. Defects in HPS3 are the cause of the cocoa (coa) mutant, and of Hermansky-Pudlak syndrome type 3 (HPS3). HPS3 is an autosomal recessive disorder, characterized by oculocutaneous albinism, bleeding due to platelet storage pool deficiency, and lysosomal storage defects. This syndrome results from defects of diverse cytoplasmic organelles including melanosomes, platelet dense granules and lysosomes. Ceroid storage in the lungs is associated with pulmonary fibrosis, a common cause of premature death in individuals with HPS.
  • 細胞内局在
    Cytoplasmic
  • 参照データベース
  • 別名
    • BLOC2S1 antibody
    • Cocoa antibody
    • DKFZp686F0413 antibody
    • FLJ22704 antibody
    • Hermansky Pudlak syndrome 3 antibody
    • Hermansky Pudlak syndrome 3 protein antibody
    • HPS3, biogenesis of lysosomal organelles complex 2 subunit 1 antibody
    • SUTAL antibody
    see all

画像

  • All lanes : Anti-HPS3 antibody (ab96343) at 1/1000 dilution

    Lane 1 : 293T whole cell lysate
    Lane 2 : A431 whole cell lysate
    Lane 3 : H1299 whole cell lysate
    Lane 4 : HeLa S3 whole cell lysate
    Lane 5 : HepG2 whole cell lysate
    Lane 6 : MOLT4 whole cell lysate
    Lane 7 : Raji whole cell lysate

    Lysates/proteins at 30 µg per lane.


    Predicted band size : 114 kDa
  • ab96343, at 1/500 dilution, staining HPS3 in paraffin-embedded SW480 by Immunohistochemistry.

参考文献

ab96343 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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