製品の概要

  • 製品名Anti-HPS3 antibody
    HPS3 一次抗体 製品一覧
  • 製品の詳細
    Goat polyclonal to HPS3
  • アプリケーション適用あり: WB, ELISAmore details
  • 種交差性

    交差が予測される動物種: Human
  • 免疫原

    Synthetic peptide:

    PYLLYCSRKKPLT

    , corresponding to C terminal amino acids 992-1004 of Human HPS3.

  • ポジティブ・コントロール
    • A431 cell lysate.

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • バッファーPreservative: 0.02% Sodium Azide
    Constituents: 0.5% BSA, Tris buffered saline. pH 7.3
  • Concentration information loading...
  • 精製度Immunogen affinity purified
  • 特記事項(精製)Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
  • ポリ/モノポリクローナル
  • アイソタイプIgG
  • 研究分野

関連製品

アプリケーション

Our Abpromise guarantee covers the use of ab19047 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 1 - 3 µg/ml. Detects a band of approximately 113 kDa (predicted molecular weight: 113 kDa).
ELISA 1/32000.

ターゲット情報

  • 関連性HPS3 is involved in early stages of melanosome biogenesis and maturation. Defects in HPS3 are the cause of the cocoa (coa) mutant, and of Hermansky-Pudlak syndrome type 3 (HPS3). HPS3 is an autosomal recessive disorder, characterized by oculocutaneous albinism, bleeding due to platelet storage pool deficiency, and lysosomal storage defects. This syndrome results from defects of diverse cytoplasmic organelles including melanosomes, platelet dense granules and lysosomes. Ceroid storage in the lungs is associated with pulmonary fibrosis, a common cause of premature death in individuals with HPS.
  • 細胞内局在Cytoplasmic
  • 参照データベース
  • 別名
    • Cocoa antibody
    • DKFZp686F0413 antibody
    • FLJ22704 antibody
    • Hermansky Pudlak syndrome 3 antibody
    • Hermansky Pudlak syndrome 3 protein antibody
    • SUTAL antibody
    see all

Anti-HPS3 antibody 画像



  • Predicted band size : 113 kDa


    ab19047 (1µg/ml) staining of A431 lysate (35µg protein in RIPA buffer) approx. 113kDa. Primary incubation was 1 hour. Detected by chemiluminescence.

Anti-HPS3 antibody (ab19047) 使用論文

This product has been referenced in:
  • Li K  et al. HPS6 interacts with dynactin p150Glued to mediate retrograde trafficking and maturation of lysosomes. J Cell Sci 127:4574-88 (2014). Read more (PubMed: 25189619) »

See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"