製品の概要

  • 製品名
  • 製品の詳細
    Mouse polyclonal to HP1BP3
  • アプリケーション
    適用あり: WBmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Full length human HP1BP3 protein, (NP_057371, 553 a.a)

  • ポジティブ・コントロール
    • HP1BP3 transfected 293T lysate.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab68719 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/500 - 1/1000. Detects a band of approximately 75 kDa (predicted molecular weight: 61 kDa).

ターゲット情報

  • 機能
    Component of heterochromatin that maintains heterochromatin integrity during G1/S progression and regulates the duration of G1 phase to critically influence cell proliferative capacity (PubMed:24830416). Mediates chromatin condensation during hypoxia, leading to increased tumor cell viability, radio-resistance, chemo-resistance and self-renewal(PubMed:25100860).
  • 配列類似性
    Contains 3 H15 (linker histone H1/H5 globular) domains.
  • ドメイン
    A central region that included the first H15 (linker histone H1/H5 globular) domain binds at the entry/exit site of the nucleosomal DNA.
  • 細胞内局在
    Nucleus. Chromosome. localized in nuclei but not in nucleoli in interphase. Colocalized with chromosomes in mitosis, with a gradually increased during G1 progression and a maximum level during late G1 phase (G1/S).
  • Information by UniProt
  • 参照データベース
  • 別名
    • Heterochromatin protein 1, binding protein 3 antibody
    • Heterochromatin protein 1-binding protein 3 antibody
    • HP1 BP74 antibody
    • HP1B3_HUMAN antibody
    • HP1BP 3 antibody
    • HP1BP3 antibody
    • MGC28927 antibody
    • MGC43701 antibody
    • MGC72624 antibody
    • OTTHUMP00000002717 antibody
    • OTTHUMP00000002719 antibody
    • OTTHUMP00000002720 antibody
    • Protein HP1 BP74 antibody
    • Protein HP1-BP74 antibody
    • RP5 930J4.3 antibody
    see all

画像

  • All lanes : Anti-HP1BP3 antibody (ab68719) at 1/500 dilution

    Lane 1 : HP1BP3 transfected 293T lysate
    Lane 2 : Non-transfected 293T lysate

    Lysates/proteins at 25 µg per lane.

    Secondary
    Goat Anti-Mouse IgG (H&L)-HRP at 1/2500 dilution

    Predicted band size : 61 kDa
    Observed band size : 75 kDa (why is the actual band size different from the predicted?)

プロトコール

参考文献

ab68719 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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