製品の概要

  • 製品名Anti-HOXD10 antibody
    HOXD10 一次抗体 製品一覧
  • 製品の詳細
    Goat polyclonal to HOXD10
  • アプリケーション適用あり: IHC-P, WBmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Mouse, Rat, Horse, Cow, Xenopus laevis, Chimpanzee
  • 免疫原

    Synthetic peptide:

    PNRSCRIEQPVTQQ

    , corresponding to internal sequence amino acids 84-97 of Human HOXD10 (NP_002139.2)

  • ポジティブ・コントロール
    • Human Kidney lysate.

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
  • バッファーPreservative: 0.02% Sodium Azide
    Constituents: 0.5% BSA, Tris buffered saline, pH 7.3
  • Concentration information loading...
  • 精製度Immunogen affinity purified
  • 特記事項(精製)Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
  • ポリ/モノポリクローナル
  • アイソタイプIgG
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab85698 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
IHC-P Use a concentration of 3 - 5 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
WB Use a concentration of 0.2 - 0.6 µg/ml. Predicted molecular weight: 38 kDa.

ターゲット情報

  • 機能Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.
  • 組織特異性Strongly expressed in the adult male and female urogenital tracts.
  • 関連疾患Defects in HOXD10 are a cause of congenital vertical talus (CVT) [MIM:192950]; also known as rocker-bottom foot deformity or congenital convex pes valgus. CVT is a dislocation of the talonavicular joint, with rigid dorsal dislocation of the navicular over the neck of the talus. This condition is usually associated with multiple other congenital deformities and only rarely is an isolated deformity.
  • 配列類似性Belongs to the Abd-B homeobox family.
    Contains 1 homeobox DNA-binding domain.
  • 発生段階Expressed in the developing limb buds.
  • 細胞内局在Nucleus.
  • Information by UniProt
  • 参照データベース
  • 別名
    • AI385591 antibody
    • AI874987 antibody
    • Homeo box 4D antibody
    • Homeo box D10 antibody
    • Homeobox D10 antibody
    • Homeobox protein Hox-4D antibody
    • Homeobox protein Hox-4E antibody
    • Homeobox protein Hox-D10 antibody
    • Hox 4.4 antibody
    • Hox 4.5 antibody
    • Hox 4D antibody
    • Hox 4E antibody
    • Hox 5.3 antibody
    • HOX4D antibody
    • HOX4E antibody
    • HOXD10 antibody
    • HXD10 antibody
    • HXD10_HUMAN antibody
    • OTTMUSP00000017845 antibody
    • RP23-313J15.9 antibody
    see all

Anti-HOXD10 antibody 画像

  • ab85698 (3.8µg/ml) staining of paraffin embedded Human Kidney following steamed antigen retrieval with citrate buffer pH 6 and AP-staining shows nuclear staining in some epithelial cells of PCT.

  • Anti-HOXD10 antibody (ab85698) at 0.2 µg/ml + Human Kidney lysate at 35 µg

    Predicted band size : 38 kDa
    Observed band size : 38 kDa
    Additional bands at : 26 kDa,90 kDa. We are unsure as to the identity of these extra bands.
    Additional bands of unknown identity were also consistently observed at 90+26 kDa. These bands were successfully blocked by incubation with the immunising peptide.

Anti-HOXD10 antibody (ab85698) 使用論文

ab85698 has not yet been referenced specifically in any publications.

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