Anti-HoxC6 抗体 (ab41587)
Key features and details
- Rabbit polyclonal to HoxC6
- Suitable for: IHC-P, WB
- Reacts with: Human
- Isotype: IgG
リコンビナント抗体で、ロット間での高い再現性を実現
- 異なるロット間での安定した再現性
- 容易なスケールアップ
- 評価試験による特異性の確認済み
- 倫理基準に準拠 - アニマル・フリーの生産
製品の概要
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製品名
Anti-HoxC6 antibody
HoxC6 一次抗体 製品一覧 -
製品の詳細
Rabbit polyclonal to HoxC6This product is a fast track antibody. It has been affinity purified and shows high titre values against the immunizing peptide by ELISA. Read the terms of use »
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由来種
Rabbit -
種交差性
交差種: Human
交差が予測される動物種: Mouse, Rat -
免疫原
Synthetic peptide corresponding to Human HoxC6 aa 100-200 conjugated to keyhole limpet haemocyanin.
(Peptide available asab41586) -
特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
バッファー
pH: 7.40
Preservative: 0.02% Sodium azide
Constituent: PBS
Batches of this product that have a concentration < 1mg/ml may have BSA added as a stabilising agent. If you would like information about the formulation of a specific lot, please contact our scientific support team who will be happy to help. -
Concentration information loading...
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精製度
Immunogen affinity purified -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
アプリケーション
Fast track antibodies constitute a diverse group of products that have been released to accelerate your research, but are not yet fully characterized. They have all been affinity purified and show high titre values against the immunizing peptide (by ELISA). Fast track terms of use
アプリケーション | Abreviews | 特記事項 |
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IHC-P | (1) |
1/50. Some customers have used this antibody successfully in IHC-P; however this is not a tested application for this antibody.
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WB |
Use at an assay dependent concentration. Predicted molecular weight: 26 kDa.
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特記事項 |
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IHC-P
1/50. Some customers have used this antibody successfully in IHC-P; however this is not a tested application for this antibody. |
WB
Use at an assay dependent concentration. Predicted molecular weight: 26 kDa. |
ターゲット情報
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機能
Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. -
配列類似性
Belongs to the Antp homeobox family.
Contains 1 homeobox DNA-binding domain. -
細胞内局在
Nucleus. - Information by UniProt
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参照データベース
- Entrez Gene: 3223 Human
- Entrez Gene: 15425 Mouse
- Entrez Gene: 252885 Rat
- Omim: 142972 Human
- SwissProt: P09630 Human
- SwissProt: P10629 Mouse
- Unigene: 549040 Human
- Unigene: 4444 Mouse
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別名
- CP25 antibody
- HHO.C8 antibody
- Homeo box 3C antibody
see all
画像
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All lanes : Anti-HoxC6 antibody (ab41587)
Lane 1 : Human ovary tissue lysate
Lane 2 : Human ovary tumor tissue lysate
Lane 3 : SK-N-BE cell lysate
Lane 4 : PC3 cell lysate
Lane 5 : MCF7 cell lysate
Lysates/proteins at 10 µg per lane.
Secondary
All lanes : Goat polyclonal Secondary Antibody to Rabbit IgG - H&L (HRP) at 1/50000 dilution
Developed using the ECL technique.
Performed under reducing conditions.
Predicted band size: 26 kDa
Observed band size: 25 kDa why is the actual band size different from the predicted?
Exposure time: 8 minutes
プロトコール
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (11)
ab41587 は 11 報の論文で使用されています。
- Wang Q et al. Multitranscriptome analyses of keloid fibroblasts reveal the role of the HIF-1α/HOXC6/ERK axis in keloid development. Burns Trauma 10:tkac013 (2022). PubMed: 35547861
- Qi ZP et al. HDAC2 promotes the EMT of colorectal cancer cells and via the modular scaffold function of ENSG00000274093.1. J Cell Mol Med 25:1190-1197 (2021). PubMed: 33325150
- Qi L et al. HomeoboxC6 promotes metastasis by orchestrating the DKK1/Wnt/ß-catenin axis in right-sided colon cancer. Cell Death Dis 12:337 (2021). PubMed: 33795652
- Yang P et al. Overexpression of HOXC6 promotes cell proliferation and migration via MAPK signaling and predicts a poor prognosis in glioblastoma. Cancer Manag Res 11:8167-8179 (2019). PubMed: 31564976
- Zhang F et al. HOXC6 gene silencing inhibits epithelial-mesenchymal transition and cell viability through the TGF-ß/smad signaling pathway in cervical carcinoma cells. Cancer Cell Int 18:204 (2018). PubMed: 30559605