Anti-Hormone sensitive lipase (phospho S853) 抗体 [EPR2329(2)] (ab109400)

製品の概要

• 製品名Anti-Hormone sensitive lipase (phospho S853) antibody [EPR2329(2)]
  Hormone sensitive lipase 一次抗体 製品一覧
• 製品の詳細
  Rabbit monoclonal [EPR2329(2)] to Hormone sensitive lipase (phospho S853)
• 特異性The antibody only detects HSL phosphorylated on serine 853.
• アプリケーション適用あり: WBmore details
  適用なし: Flow Cyt,ICC,IHC-P or IP
• 種交差性
  交差種: Mouse, Rat, Human
  
• 免疫原

  Phospho-specific peptide corresponding to residues surrounding serine 853 of Human HSL/LIPE (UniProt Q05469).

• ポジティブ･コントロール
  • Human skeletal muscle lysates and Mouse muscle lysates
• 特記事項

  This product is a recombinant rabbit monoclonal antibody.

  Produced using Abcam’s RabMAb^® technology. RabMAb^® technology is covered by the following U.S. Patents, No. 5,675,063 and/or 7,429,487.

製品の特性

• 製品の状態Liquid
• 保存方法Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C.
• バッファーPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
• 精製度Tissue culture supernatant
• ポリ/モノモノクローナル
• クローン名EPR2329(2)
• アイソタイプIgG
• 研究分野
  • Cardiovascular
  • Lipids / Lipoproteins
  • Lipid Metabolism
  • Lipases

  • Cardiovascular
  • Lipids / Lipoproteins
  • Lipid Metabolism
  • Cholesterol Metabolism

  • Signal Transduction
  • Metabolism
  • Lipid metabolism

  • Cancer
  • Cancer Metabolism
  • Metabolic signaling pathway
  • Metabolism of lipids and lipoproteins

  • Metabolism
  • Pathways and Processes
  • Metabolic signaling pathways
  • Lipid and lipoprotein metabolism
  • Lipid metabolism

  • Metabolism
  • Pathways and Processes
  • Metabolic signaling pathways
  • Lipid and lipoprotein metabolism
  • Cholesterol Metabolism

  • Metabolism
  • Pathways and Processes
  • Metabolic signaling pathways
  • Lipid and lipoprotein metabolism
  • Lipases

  • Metabolism
  • Types of disease
  • Cancer

アプリケーション

ターゲット情報

• 機能In adipose tissue and heart, it primarily hydrolyzes stored triglycerides to free fatty acids, while in steroidogenic tissues, it principally converts cholesteryl esters to free cholesterol for steroid hormone production.
• パスウェイGlycerolipid metabolism; triacylglycerol degradation.
• 配列類似性Belongs to the 'GDXG' lipolytic enzyme family.
• 細胞内局在Cell membrane. Membrane > caveola. Cytoplasm > cytosol. Found in the high-density caveolae. Translocates to the cytoplasm from the caveolae upon insulin stimulation.

• Target information above from: UniProt accession Q05469 The UniProt Consortium
  The Universal Protein Resource (UniProt) in 2010
  Nucleic Acids Res. 38:D142-D148 (2010) .

  Information by UniProt
• 参照データベース
  • Entrez Gene: 3991 Human
  • Entrez Gene: 16890 Mouse
  • Entrez Gene: 25330 Rat
  • Omim: 151750 Human
  • SwissProt: Q05469 Human
  • SwissProt: Q6NSL7 Human
  • SwissProt: P54310 Mouse
  • SwissProt: P15304 Rat

  • Unigene: 656980 Human
  • Unigene: 158548 Mouse
  • Unigene: 333679 Mouse
  • Unigene: 10566 Rat

  see all
• 別名
  • Hormone sensitive lipase antibody
  • Hormone sensitive lipase testicular isoform antibody
  • Hormone-sensitive lipase antibody

  • HSL antibody
  • LHS antibody
  • Lipase hormone sensitive antibody
  • LIPE antibody
  • LIPS_HUMAN antibody

  see all