製品の概要

  • 製品名Anti-HOOK2 antibody
    HOOK2 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to HOOK2
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Mouse, Rat
  • 免疫原

    Synthetic peptide conjugated to KLH derived from within residues 700 to the C-terminus of Mouse HOOK2.

    (Peptide available as ab101733.)

  • ポジティブ・コントロール
    • This antibody gave a positive signal in human brain tissue lysate.

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • バッファーPreservative: 0.02% Sodium Azide
    Constituents: 1% BSA, PBS, pH 7.4
  • Concentration information loading...
  • 精製度Immunogen affinity purified
  • ポリ/モノポリクローナル
  • アイソタイプIgG
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab89696 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 1 µg/ml. Detects a band of approximately 83 kDa (predicted molecular weight: 83 kDa).

ターゲット情報

  • 関連性HOOK2 is a member of the Hook protein family. Hook proteins are cytosolic coiled-coil proteins that contain conserved N-terminal domains, which attach to microtubules, and more divergent C-terminal domains, which mediate binding to organelles. HOOK2 localizes to the centrosome through all phases of the cell cycle. Interference with HOOK2 function results in the loss of the radial organization of microtubules suggesting that HOOK2 contributes to the establishment and maintenance of centrosomal structure and function. HOOK2 may contribute to the establishment and maintenance of the pericentrosomal localization of aggresomes by promoting the microtubule-based delivery of protein aggregates to pericentriolar aggresomes.
  • 細胞内局在Cytoplasmic. Note=Associates with discrete punctate structure that correspond to neither early or late endosomes, lysosomes, multivesicular bodies (MVBs), Golgi complex, endoplasmic reticulum, nor mitochondria.
  • 参照データベース
  • 別名
    • A630054I03Rik antibody
    • FLJ26218 antibody
    • h hook2 antibody
    • hHK 2 antibody
    • hHK2 antibody
    • hhook 2 antibody
    • hhook2 antibody
    • HK 2 antibody
    • HK2 antibody
    • HOOK 2 antibody
    • hook homolog 2 (Drosophila) antibody
    • Hook homolog 2 antibody
    • MGC28586 antibody
    • MGC91008 antibody
    see all

Anti-HOOK2 antibody 画像

  • Anti-HOOK2 antibody (ab89696) at 1 µg/ml + Human brain tissue lysate - total protein (ab29466) at 10 µg

    Secondary
    Goat Anti-Rabbit IgG H&L (HRP) preadsorbed (ab97080) at 1/5000 dilution
    Developed using the ECL technique

    Performed under reducing conditions.

    Predicted band size : 83 kDa
    Observed band size : 83 kDa
    Additional bands at : 23 kDa. We are unsure as to the identity of these extra bands.

    Exposure time : 20 minutes

Anti-HOOK2 antibody (ab89696) 使用論文

ab89696 has not yet been referenced specifically in any publications.

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