製品の概要

  • 製品名Anti-hnRNP L antibody
    hnRNP L 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to hnRNP L
  • アプリケーション適用あり: ELISA, ICC/IF, IHC-P, WBmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Mouse
  • 免疫原

    Synthetic peptide from N terminal of human hnRNP L.

  • ポジティブ・コントロール
    • Human colon carcinoma tissue, HeLa, Jurkat and HUVEC cell extracts and HeLa cells.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab65049 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
ELISA 1/20000.
ICC/IF 1/500 - 1/1000.
IHC-P 1/50 - 1/100.
WB 1/500 - 1/1000. Detects a band of approximately 60 kDa (predicted molecular weight: 60 kDa).

ターゲット情報

  • 機能This protein is a component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complexes which provide the substrate for the processing events that pre-mRNAs undergo before becoming functional, translatable mRNAs in the cytoplasm. Is associated with most nascent transcripts including those of the landmark giant loops of amphibian lampbrush chromosomes. Associates, together with APEX1, to the negative calcium responsive element (nCaRE) B2 of the APEX2 promoter.
  • 配列類似性Contains 3 RRM (RNA recognition motif) domains.
  • 翻訳後修飾Several isoelectric forms of the L protein are probably the results of post-translational modifications.
  • 細胞内局在Nucleus > nucleoplasm. Cytoplasm. Localized in cytoplasmic mRNP granules containing untranslated mRNAs.
  • Information by UniProt
  • 参照データベース
  • 別名
    • D830027H13Rik antibody
    • FLJ35509 antibody
    • Heterogeneous nuclear ribonucleoprotein L antibody
    • hnRNP L antibody
    • hnRNP-L antibody
    • Hnrnpl antibody
    • hnRPL antibody
    • HNRPL_HUMAN antibody
    • P/OKcl.14 antibody
    see all

Anti-hnRNP L antibody 画像

  • ab65049 at 1/500 dilution staining hnRNP L in HeLa cells by Immunofluorescence, in the absence or presence of the immunising peptide.
  • ab65049 at 1/50 dilution staining hnRNP L in human colon carcinoma by Immunohistochemistry, Paraffin-embedded tissue, in the absence or presence of the immunising peptide.
  • All lanes : Anti-hnRNP L antibody (ab65049) at 1/500 dilution

    Lane 1 : HeLa cell extract
    Lane 2 : Jurkat cell extract
    Lane 3 : HUVEC cell extract
    Lane 4 : HUVEC cell extract with immunising peptide at 5 µg

    Lysates/proteins at 5 µg per lane.


    Predicted band size : 60 kDa
    Observed band size : 60 kDa

Anti-hnRNP L antibody (ab65049) 使用論文

This product has been referenced in:
  • Roda D  et al. EGF-Induced Acetylation of Heterogeneous Nuclear Ribonucleoproteins Is Dependent on KRAS Mutational Status in Colorectal Cancer Cells. PLoS One 10:e0130543 (2015). Human . Read more (PubMed: 26110767) »
  • Li J  et al. HnRNPL as a key factor in spermatogenesis: Lesson from functional proteomic studies of azoospermia patients with sertoli cell only syndrome. J Proteomics : (2012). WB ; Human . Read more (PubMed: 22245417) »

See all 4 Publications for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"