製品の概要

  • 製品名
  • 製品の詳細
    Rabbit polyclonal to hnRNP H
  • アプリケーション
    適用あり: IHC-Pmore details
  • 種交差性
    交差種: Mouse, Human
    交差が予測される動物種: Rat, Rabbit, Horse, Guinea pig, Dog, Pig, Chimpanzee, Rhesus monkey, Gorilla, Opossum, Orangutan, Elephant
  • 免疫原

    Synthetic peptide corresponding to a region between residue 400 and the C-terminus (residue 448) of Human hnRNP H (NP_005511.1).

  • ポジティブ・コントロール
    • Human prostate adenocarcinoma. Mouse squamous cell carcinoma.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab84428 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
IHC-P
  • 追加情報
    IHC-P: 1/100 - 1/500. Epitope exposure is recommended. Epitope exposure with citrate buffer will enhance staining.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 機能
      This protein is a component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complexes which provide the substrate for the processing events that pre-mRNAs undergo before becoming functional, translatable mRNAs in the cytoplasm. Mediates pre-mRNA alternative splicing regulation. Inhibits, together with CUGBP1, insulin receptor (IR) pre-mRNA exon 11 inclusion in myoblast. Binds to the IR RNA. Binds poly(RG).
    • 組織特異性
      Expressed ubiquitously.
    • 配列類似性
      Contains 3 RRM (RNA recognition motif) domains.
    • ドメイン
      Each quasi-RRM repeat bound poly(RG), while only the N-terminal QRRM bound poly(RC) and poly(RU). None of the repeats bound detectable amounts of poly(RA).
    • 細胞内局在
      Nucleus > nucleoplasm.
    • Information by UniProt
    • 参照データベース
    • 別名
      • DKFZp686A15170 antibody
      • Heterogeneous nuclear ribonucleoprotein H antibody
      • Heterogeneous nuclear ribonucleoprotein H1 (H) antibody
      • Heterogeneous nuclear ribonucleoprotein H1 antibody
      • HNRH1_HUMAN antibody
      • hnRNP H antibody
      • hnRNPH antibody
      • Hnrnph1 antibody
      • HNRPH 1 antibody
      • HNRPH antibody
      • HNRPH1 protein antibody
      • N-terminally processed antibody
      see all

    画像

    • ab84428, at 1/250 dilution, staining hnRNP H in formalin-fixed, paraffin-embedded human prostate adenocarcinoma by Immunohistochemistry using DAB detection and an anti-Rabbit IgG HRP conjugated secondary antibody at a dilution of 1/100.
    • ab84428, at 1/250 dilution, staining hnRNP H in formalin-fixed, paraffin-embedded mouse squamous cell carcinoma by Immunohistochemistry using DAB detection and an anti-Rabbit IgG HRP conjugated secondary antibody at a dilution of 1/100.

    プロトコール

    参考文献

    ab84428 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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