製品の概要

  • 製品名Anti-HMW Cytokeratin antibody [34bE12]
    HMW Cytokeratin 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal [34bE12] to HMW Cytokeratin
  • 特異性This antibody recognizes the HMW (High Molecular Weight) keratin polypeptides of 68, 58, 56.5 and 50 kDa in extract of stratum corneum. The antibody reacts with squamous, ductal and other complex epithelia. It stains adenocarcinomas, breast, pancreas, bile duct, salivary gland and transitional cell carcinomas.
  • アプリケーション適用あり: IHC-P, IHC-Frmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Solubilized keratin extract from human stratum corneum.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab776 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
IHC-P
IHC-Fr
  • 追加情報IHC: This antibody may be diluted to a titer of 1:25-1:50 in an ABC method.
    Staining Protocol: We suggest an incubation period of 30-60 minutes at room temperature.
    However, depending upon the fixation conditions and the staining system employed, optimal incubation conditions and antibody dilutions should be determined by the user.
    Enzymatic antigen retrieval of paraffin embedded tissues is recommended prior to immunostaining.
  • ターゲット情報

    • 関連性Cytokeratins are intermediate filament keratins found in the intracytoplasmic cytoskeleton of epithelial tissue. There are two types of Cytokeratins: the low weight, acidic type I cytokeratins and the high weight, basic or neutral type II. Cytokeratins are usually found in pairs comprising a type I Cytokeratin and a type II cytokeratin. The high molecular weight cytokeratins, which are the basic or neutral cytokeratins, comprise subtypes CK1 (67), CK2 (65.5), CK3 (64), CK4 (59), CK5 (58), CK6 (56), CK7 (54), CK8 (52.5) and CK9. The low molecular weight cytokeratins, which are the acidic cytokeratins, comprise subtypes CK10 (56.5), CK12 (56), CK13 (53), CK14 (50), CK16( 48), CK17 (46), CK18 (45), CK19(48) and CK20(46).
    • 細胞内局在Cytoplasmic
    • 参照データベース
    • 別名
      • CK13 antibody
      • CK14 antibody
      • CK15 antibody
      • CK16 antibody
      • Cytokeratin 13 antibody
      • Cytokeratin 14 antibody
      • Cytokeratin 15 antibody
      • Cytokeratin 16 antibody
      • K13 antibody
      • K14 antibody
      • K15 antibody
      • K16 antibody
      • Keratin 13 antibody
      • Keratin 14 antibody
      • Keratin 15 antibody
      • Keratin 15, basic antibody
      • Keratin 15, beta antibody
      • Keratin 16 antibody
      • KRT13 antibody
      • KRT14 antibody
      • KRT15 antibody
      • KRT16 antibody
      • KRT16A antibody
      see all

    Anti-HMW Cytokeratin antibody [34bE12] 画像

    • ab776 - immunohistochemistry

      Formalin fixed paraffin embedded human colon carcinoma stained with HMW Cytokeratin, using ABC and AEC chromagen.

    • ab776 staining human skin tissue sections by IHC-P.

    Anti-HMW Cytokeratin antibody [34bE12] (ab776) 使用論文

    This product has been referenced in:
    • Hagman Z  et al. miR-205 negatively regulates the androgen receptor and is associated with adverse outcome of prostate cancer patients. Br J Cancer 108:1668-76 (2013). IHC ; Human . Read more (PubMed: 23571738) »

    See 1 Publication for this product

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"