製品の概要

  • 製品名Anti-HMGN3 antibody
    HMGN3 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to HMGN3
  • アプリケーション適用あり: IHC-P, IPmore details
    適用なし: WB
  • 種交差性
    交差種: Human
    交差が予測される動物種: Chimpanzee, Rhesus monkey, Gorilla, Orangutan
  • 免疫原

    Synthetic peptide corresponding to a region between residues 30 and 60 of human HMGN3 (NP_004233.1).

  • ポジティブ・コントロール
    • HeLa whole cell lysate.

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • バッファーPreservative: 0.09% Sodium Azide
    Constituents: 8mM PBS, 60mM Citrate, 150mM Tris, pH 7-8
  • Concentration information loading...
  • 精製度Immunogen affinity purified
  • 特記事項(精製)ab72232 was affinity purified using an epitope specific to HMGN3 immobilized on solid support.
  • ポリ/モノポリクローナル
  • アイソタイプIgG
  • 研究分野

関連製品

アプリケーション

Our Abpromise guarantee covers the use of ab72232 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
IHC-P 1/500 - 1/2000. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
IP Use at 2-5 µg/mg of lysate.
  • 追加情報Is unsuitable for WB.
  • ターゲット情報

    • 機能Binds to nucleosomes, regulating chromatin structure and consequently, chromatin-dependent processes such as transcription, DNA replication and DNA repair. Affects both insulin and glucagon levels and modulates the expression of pancreatic genes involved in insulin secretion. Regulates the expression of the glucose transporter SLC2A2 by binding specifically to its promoter region and recruiting PDX1 and additional transcription factors. Regulates the expression of SLC6A9, a glycine transporter which regulates the glycine concentration in synaptic junctions in the central nervous system, by binding to its transcription start site. May play a role in ocular development and astrocyte function.
    • 組織特異性Expressed in kidney, lung, pancreas, testis, skeletal muscle, heart, thyroid gland, pituitary gland, prostate and uterus. Low expression in liver, spleen, placenta and ovaries.
    • 配列類似性Belongs to the HMGN family.
    • 細胞内局在Nucleus.
    • Information by UniProt
    • 参照データベース
    • 別名
      • DKFZp686E20226 antibody
      • FLJ42187 antibody
      • High mobility group nucleosomal binding domain 3 antibody
      • High mobility group nucleosome-binding domain-containing protein 3 antibody
      • HMGN3 antibody
      • HMGN3_HUMAN antibody
      • OTTHUMP00000016772 antibody
      • OTTHUMP00000016773 antibody
      • PNAS 24 antibody
      • PNAS 25 antibody
      • PNAS24 antibody
      • PNAS25 antibody
      • Thyroid hormone receptor interacting protein 7 antibody
      • Thyroid receptor-interacting protein 7 antibody
      • TR-interacting protein 7 antibody
      • TRIP 7 antibody
      • TRIP-7 antibody
      • TRIP7 antibody
      see all

    Anti-HMGN3 antibody 画像

    • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of human prostate carcinoma tissue labelling HMGN3 with ab72232 at 1/1000 (1µg/ml). Detection: DAB.

    Anti-HMGN3 antibody (ab72232) 使用論文

    ab72232 has not yet been referenced specifically in any publications.

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    There are currently no Abreviews or Questions for ab72232.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"