製品の概要

  • 製品名Anti-HLA DR + HLA DP antibody [MEM-136] (FITC)
    HLA DR + HLA DP 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal [MEM-136] to HLA DR + HLA DP (FITC)
  • 標識FITC. Ex: 493nm, Em: 528nm
  • 特異性ab77237 recognizes common epitope on beta-chain of human HLA-DR and HLA-DP. It reacts with alpha/beta dimer as well as with dissociated beta-subunit.
  • アプリケーション適用あり: Flow Cytmore details
  • 種交差性
    交差種: Human
  • 免疫原

    PHA-activated peripheral blood lymphocytes.

  • ポジティブ・コントロール
    • Human blood cells.
  • 特記事項

    The purified antibody is conjugated with Fluorescein isothiocyanate (FITC) under optimum conditions. The reagent is free of unconjugated FITC and adjusted for direct use.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab77237 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
Flow Cyt
  • 追加情報Flow Cyt: Use 20µl for 106 cells or 100µl whole blood.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 関連性Human MHC class II antigens are transmembrane glycoproteins composed of an alpha (36 kDa) and a beta chain (27kDa) and are expressed primarily on antigen presenting cells. Human MHC class II genes are located in the HLA-D region that encodes at least 6 alpha and 10 beta chain genes. Three loci, DR, DQ and DP, encode the major products of the human class II region. The human MHC class II molecules bind intracellularly processed peptides and present them to T-helper cells and therefore have a critical role in the initiation of the immune response. It has been shown that some autoimmune diseases are associated with certain class II alleles.
    • 細胞内局在Cell Membrane; Single pass type I membrane protein
    • 参照データベース
    • 別名
      • HLA DP antibody
      • HLA DR antibody
      • MHC Class II antibody

    Anti-HLA DR + HLA DP antibody [MEM-136] (FITC) (ab77237) 使用論文

    This product has been referenced in:
    • Koch C  et al. T cell activation-associated epitopes of CD147 in regulation of the T cell response, and their definition by antibody affinity and antigen density. Int Immunol 11:777-86 (1999). Read more (PubMed: 10330283) »

    See 1 Publication for this product

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    There are currently no Abreviews or Questions for ab77237.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"