製品の概要

  • 製品名Anti-HLA DR + HLA DP antibody [HL-38]
    HLA DR + HLA DP 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal [HL-38] to HLA DR + HLA DP
  • 特異性The antibody also reacts with porcine MHC class II antigens (SLA-D gene products).
  • アプリケーション適用あり: Flow Cyt, IP, WBmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Tissue/ cell preparation (Human). (Burkitt lymphoma cell line Raji).

  • エピトープThis antibody binds to a common epitope on the b-chain of human HLA-DR and HLA-DP.

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • バッファーPreservative: 15mM Sodium Azide
    Constituents: PBS, pH 7.4
  • Concentration information loading...
  • 精製度>95% by SDS-PAGE
  • 特記事項(精製)Purified from ascites by protein-A affinity chromatography.
  • ポリ/モノモノクローナル
  • クローン名HL-38
  • アイソタイプIgG2a
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab766 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
Flow Cyt
IP
WB
  • 追加情報Flow Cyt: Use at an assay dependant concentration.
    IP: Use at an assay dependant concentration.
    WB: Use at an assay dependant concentration. Use under non-reducing conditions.

    Not tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 関連性Human MHC class II antigens are transmembrane glycoproteins composed of an alpha (36 kDa) and a beta chain (27kDa) and are expressed primarily on antigen presenting cells. Human MHC class II genes are located in the HLA-D region that encodes at least 6 alpha and 10 beta chain genes. Three loci, DR, DQ and DP, encode the major products of the human class II region. The human MHC class II molecules bind intracellularly processed peptides and present them to T-helper cells and therefore have a critical role in the initiation of the immune response. It has been shown that some autoimmune diseases are associated with certain class II alleles.
    • 細胞内局在Cell Membrane; Single pass type I membrane protein
    • 参照データベース
    • 別名
      • HLA DP antibody
      • HLA DR antibody
      • MHC Class II antibody

    Anti-HLA DR + HLA DP antibody [HL-38] (ab766) 使用論文

    This product has been referenced in:
    • Horejsi­ V  et al. Monoclonal antibodies against human leucocyte antigens. I. Antibodies against beta-2-microglobulin, immunoglobulin kappa light chains, HLA-DR-like antigens, T8 antigen, T1 antigen, a monocyte antigen, and a pan-leucocyte antigen. Folia Biol (Praha) 32:12-25 (1986). Read more (PubMed: 2422063) »

    See 1 Publication for this product

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"