製品の概要

  • 製品名
    Anti-HLA DMA antibody
  • 製品の詳細
    Rabbit polyclonal to HLA DMA
  • アプリケーション
    適用あり: WB, IHC-Pmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Recombinant fragment corresponding to Human HLA DMA aa 52-255.
    Database link: AAH11447

  • ポジティブ・コントロール
    • WB: HeLa whole cell lysates. IHC-P: Human breast cancer tissue.

法規制情報

製品の特性

  • 製品の状態
    Liquid
  • 保存方法
    Shipped at 4°C. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • バッファー
    Preservative: 0.01% Thimerosal (merthiolate)
    Constituents: 20% Glycerol, 0.1M Tris, 0.1M Glycine, pH 7.0
  • Concentration information loading...
  • 精製度
    Immunogen affinity purified
  • ポリ/モノ
    ポリクローナル
  • アイソタイプ
    IgG
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab96664 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/500 - 1/3000. Predicted molecular weight: 29 kDa.
IHC-P 1/250.

ターゲット情報

  • 関連性
    Human Leukocyte Antigens are highly polymorphic proteins that are involved in the presentation of antigens to the T-cell receptor. There are two classes of HLA antigens, class I (HLA-A, HLA-B and HLA-C) and class II (HLA-D). This antibody can be used for HLA typing. HLA DM plays a critical role in catalyzing the release of class II HLA-associated invariant chain-derived peptides (CLIP) from newly synthesized class II HLA molecules and freeing the peptide binding site for acquisition of antigenic peptides.
  • 細胞内局在
    Late endosome membrane; Single-pass type I membrane protein. Lysosome membrane; Single-pass type I membrane protein. Note: Localizes to late endocytic compartment. Associates with lysosome membranes.
  • 参照データベース
  • 別名
    • Class II histocompatibility antigen M alpha chain antibody
    • D6S222E antibody
    • DMA antibody
    • HLA class II histocompatibility antigen DM alpha chain antibody
    • HLA DMA antibody
    • HLADM antibody
    • Major histocompatibility complex class II DM alpha antibody
    • MHC class II antigen DMA antibody
    • OTTHUMP00000029242 antibody
    • OTTHUMP00000062997 antibody
    • OTTHUMP00000178727 antibody
    • OTTHUMP00000178728 antibody
    • OTTHUMP00000178729 antibody
    • Really interesting new gene 6 protein antibody
    • Ring 6 antibody
    • Ring6 antibody
    see all

画像

  • Anti-HLA DMA antibody (ab96664) at 1/1000 dilution + HeLa whole cell lysate at 30 µg

    Predicted band size : 29 kDa
    12% SDS PAGE
  • Immunohistochemical (Formalin/PFA-fixed pparaffin-embedded) analysis of human breast cancer tissue labelling HLA DMA with ab96664 at a 1/250 dilution.

プロトコール

参考文献

ab96664 has not yet been referenced specifically in any publications.

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