製品の概要

  • 製品名
    Anti-HLA B27 antibody [EP-4]
    HLA B27 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal [EP-4] to HLA B27
  • アプリケーション
    適用あり: ICCmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Tissue/ cell preparation. Lymphocytes from HLA-B27 individual.

  • ポジティブ・コントロール
    • Blood
  • 特記事項


    ab24094 recognizes the HLA B27 cell surface antigen on human cells. It may be used to HLA type human lymphoctyes. Approximately 60% of patients with ankylosing spondylitis are HLA B27 positive. This reagent can be used to help identify this HLA haplotype in human lymphocytes.

製品の特性

  • 製品の状態
    Liquid
  • 保存方法
    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • バッファー
    Preservative: 0.05% Sodium azide
    Constituent: PBS
  • Concentration information loading...
  • 精製度
    Purified IgM
  • 一次抗体 備考
    ab24094 recognizes the HLA B27 cell surface antigen on human cells. It may be used to HLA type human lymphoctyes. Approximately 60% of patients with ankylosing spondylitis are HLA B27 positive. This reagent can be used to help identify this HLA haplotype in human lymphocytes.
  • ポリ/モノ
    モノクローナル
  • クローン名
    EP-4
  • アイソタイプ
    IgM
  • 軽鎖の種類
    kappa
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab24094 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
ICC Use at an assay dependent concentration.

For use with paraformaldehyde fixed cell suspensions or cytospins.

ターゲット情報

  • 関連性
    Involved in the presentation of foreign antigens to the immune system. HLA B belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta 2 microglobulin). The heavy chain is anchored in the membrane. Class I molecules play a central role in the immune system by presenting peptides derived from the endoplasmic reticulum lumen. They are expressed in nearly all cells.
  • 細胞内局在
    Single-pass type 1 membrane protein
  • 参照データベース
  • 別名
    • HLAB antibody
    • Leukocyte antigen class I B antibody
    • Lymphocyte antigen antibody
    • Major histocompatibility complex class I B antibody
    • SPDA1 antibody
    see all

参考文献

ab24094 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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