製品の概要

  • 製品名Anti-HIV2 gp36 antibody [BDI411]
    HIV2 gp36 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal [BDI411] to HIV2 gp36
  • 特異性HIV2 gp36 antigen.
  • アプリケーション適用あり: WB, ELISA, IPmore details
  • 免疫原

    Recombinant fragment, corresponding to amino acids 390 - 702 of HIV2 gp36.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab20452 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB
ELISA
IP
  • 追加情報ELISA: 1/500. IP: Use at an assay dependent dilution. WB: 1/1000. Dilution optimised using Chromogenic detection. Not tested in other applications. Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 関連性HIV2 infections at present, are predominantly found in west Africa where it is the dominant form of HIV. Both HIV1 and HIV2 have the same modes of transmission and are associated with similar opportunistic infections and AIDS. In persons infected with HIV2, immunodeficiency seems to develop more slowly and to be milder, but as the disease advances, HIV2 infectiousness seems to increase. Little is known about the best approach to the clinical treatment and care of patients infected with HIV2. Some drugs used to treat HIV1 are ineffective. HIV1 and HIV2 have similar gag (viral core) and pol (polymerase) regions, they have relatively dissimilar env (envelope) regions. Owing to this lack of homology in the envelope region, there is little serologic cross-reactivity of the antibodies directed against the envelope antigens of both HIV1 and HIV2. The env gp36 ectodomain is highly conserved and elicits a type-specific antibody response. Hence, most licensed diagnostic assays incorporate gp36-derived antigens to detect HIV2 specific antibodies. It is becoming important to differentiate between single infection with either HIV1 or HIV2 and dual infection.
    • 別名
      • Gp36 antibody
      • HIV 2 antibody
      • Human immunodeficiency virus 2 antibody

    Anti-HIV2 gp36 antibody [BDI411] (ab20452) 使用論文

    ab20452 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"