製品の概要

  • 製品名
    Anti-HIV1 Vif antibody [319]
  • 製品の詳細
    Mouse monoclonal [319] to HIV1 Vif
  • 特異性
    ab66643 is specific for bacterial HIV1 Vif protein.
  • アプリケーション
    適用あり: WB, ICC/IFmore details
  • 種交差性
    Reacts with HIV1.
  • 免疫原

    Bacterially expressed, hexahistidine amino-terminal tagged HIV1 Vif protein (clade B, HXB-3 isolate).

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab66643 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/1000. Predicted molecular weight: 23 kDa.
ICC/IF Use at an assay dependent dilution.

ターゲット情報

  • 関連性
    HIV1 Vif (viral infectivity factor), supports productive viral replication in non-permissive cells, such as peripheral blood lymphocytes. It functions by inactivating a cellular anti-viral factor named APOBEC3G. Vif binds viral RNA and affects the stability of viral nucleoprotein core. May play a role in viral morphology. Interacts with host ABCE1, which seems to be involved in lentiviruses capsid formation and displays RNase L inhibitor activity. This interaction may play a role in protecting viral RNA from damage during viral assembly.
  • 別名
    • SOR protein antibody
    • Virion infectivity factor antibody

Anti-HIV1 Vif antibody [319] (ab66643) 使用論文

This product has been referenced in:
  • Desimmie BA  et al. Identification of a tripartite interaction between the N-terminus of HIV-1 Vif and CBFß that is critical for Vif function. Retrovirology 14:19 (2017). Read more (PubMed: 28302150) »
  • Nakashima M  et al. Structural Insights into HIV-1 Vif-APOBEC3F Interaction. J Virol 90:1034-47 (2015). Read more (PubMed: 26537685) »

See all 3 Publications for this product

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For ab42361: DISCOUNT CODE: ***

For ab66643: DISCOUNT CODE: ***

Expiration date: August 5th, 2012

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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