製品の概要

  • 製品名Anti-HIV1 Nef antibody
    HIV1 Nef 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to HIV1 Nef
  • アプリケーション適用あり: WB, ELISAmore details
  • 種交差性
    Reacts with HIV1.
  • 免疫原

    Recombinant Nef protein over-expressed in E. coli with a plasmid carrying the Nef coding region of HIV1 virus, subtype B.

  • ポジティブ・コントロール
    • Extract of MT4 cells uninfected or infected with HIV1 (LAI strain).

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab63918 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/1000. Predicted molecular weight: 24 kDa.
ELISA Use at an assay dependent dilution.

ターゲット情報

  • 関連性Nef is a early protein that appears to play a role in optimizing the host cell environment for viral replication without causing cell death by apoptosis. Nef enhances virus infectivity and pathogenicity. It down modulates surface MHC I molecules and internalized molecules are sequested to the trans-Golgi network. The number of cell surface CD4 antigen are decreased by interacting with the Src family kinase LCK thereby inducing LCK CD4 dissociation and by increasing clathrin-dependent endocytosis of this antigen to target it to lysosomal degradation.
  • 別名
    • C terminal core protein antibody
    • F protein antibody
    • Nef antibody
    • Negative factor antibody
    • p27 antibody
    see all

Anti-HIV1 Nef antibody 画像

  • All lanes : Anti-HIV1 Nef antibody (ab63918) at 1/1000 dilution

    Lane 1 : Extract of MT4 cells
    Lane 2 : Extract of MT4 cells infected with HIV1 (LAI strain)


    Predicted band size : 24 kDa
    Observed band size : 27 kDa (why is the actual band size different from the predicted?)

Anti-HIV1 Nef antibody (ab63918) 使用論文

ab63918 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab63918.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"