HRP Anti-HIV1 gp120 抗体 (ab53840)
Key features and details
- HRP Goat polyclonal to HIV1 gp120
- Suitable for: WB, ELISA, IHC-Fr
- Reacts with: Human immunodeficiency virus
- Conjugation: HRP
- Isotype: IgG
製品の概要
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製品名
HRP Anti-HIV1 gp120 antibody
HIV1 gp120 一次抗体 製品一覧 -
製品の詳細
HRP Goat polyclonal to HIV1 gp120 -
由来種
Goat -
標識
HRP -
特異性
Gp120 is the predominant band in WB. -
アプリケーション
適用あり: WB, ELISA, IHC-Frmore details -
種交差性
交差種: Human immunodeficiency virus -
免疫原
Full length native protein, from strain IIIB.
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特記事項
Estimated molar HRP:IgG substitution is 2-3. Free enzyme is absent.
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C. -
バッファー
Preservative: 0.002% Thimerosal (merthiolate)
Constituents: 1% BSA, PBS -
Concentration information loading...
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特記事項(精製)
>95% -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
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アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab53840の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
---|---|---|
WB | (1) |
1/20 - 1/200.
|
ELISA |
1/200 - 1/1000.
|
|
IHC-Fr |
1/20 - 1/200.
|
特記事項 |
---|
WB
1/20 - 1/200. |
ELISA
1/200 - 1/1000. |
IHC-Fr
1/20 - 1/200. |
ターゲット情報
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関連性
HIV1 is equipped with the envelope gp160 glycoprotein for interaction with Langerhans cells (LCs) and dendritic cells (DCs), the members of the innate immune system, which confront the virus at the portal of virus entry in the human body. These cells are equipped with receptors by which they bind and endocytose the virus. The gp120 glycoprotein is used for binding to CD4 receptor and CCR5 co-receptor of T helper 2 (Th2) cells, and is able to induce FcepsilonRI(+) hematopoietic cells to produce IL4, which inactivates the host adaptive immune response. -
細胞内局在
Envelope surface glycoprotein. -
参照データベース
- Entrez Gene: 155971 Human immunodeficiency virus
- GenBank: AAG28611 Human immunodeficiency virus
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別名
- Glycoprotein 120 antibody
- gp120 antibody
- SU antibody
- Surface protein antibody
プロトコール
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (1)
ab53840 は 1 報の論文で使用されています。
- Grimm SK et al. Directed evolution of a yeast-displayed HIV-1 SOSIP gp140 spike protein toward improved expression and affinity for conformational antibodies. PLoS One 10:e0117227 (2015). WB . PubMed: 25688555