製品の概要

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab6539 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
Dot blot 1/3000.
WB 1/3000. Predicted molecular weight: 37 kDa.
IP 1/750.

ターゲット情報

  • 関連性The transcriptional transactivator (Tat) is a key regulatory protein of HIV. It is expressed early after the virus integrates into the cell, and stimulates the elongation of RNA polymerase II. It binds onto a sequence known as the TAR, or transactivator response element, located at the end of the HIV genetic chain. There, the tat protein helps assemble new copies of HIV. The tat protein-TAR complex speeds up the rate of viral reproduction by about a thousand times. If it is not present, the transcription process frequently stops short, and few functional HIV particles are produced. Tat is an important potential target for antiretrovirals and vaccine development.
  • 別名
    • p14 antibody
    • Tat antibody
    • Tat protein antibody
    • Transactivating regulatory protein antibody

Anti-HIV tat antibody (ab6539) 使用論文

ab6539 has not yet been referenced specifically in any publications.

Product Wall

Thank you for contacting us. Because we carry over 90,000 products, it isn't feasible for us to keep small sample sizes of our products.

We are happy to reassure our customers that all of our products are covered by our Abpromise, which guar...

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Thank you for contacting us.

The immunogen for ab24778 is within the first 37 amino acids of human HIV TAT protein. For ab6539, the immunogen is full length TAT protein tagged with a GST fusion protein. However, we have not mapped the exact e...

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Thank you for your enquiry. The amino acid sequence used was 49-57. As we mentioned, the literature search yielded the following corresponding aa- Arg-Lys-Lys-Arg-Arg-Gln-Arg-Arg-Arg. This antibody will recognize and detect wild type HIV-TAT pro...

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According to the Cambridge University Press (online search)- Arg-Lys-Lys-Arg-Arg-Gln-Arg-Arg-Arg Hope this helps-

I am very sorry for the delay in responding to you. The source of the antibody told us: "This concern is a little puzzling, because this antisera is from a large pool that we have been selling consistently since the 1990’s. This antisera has been s...

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Thank you for your inquiry. The portion of TAT used was aa49-57. Hope this helps.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"