Histone H4 (acetyl K8) Quantification Kit (Fluorometric) (ab115119)

製品の概要

  • 製品名Histone H4 (acetyl K8) Quantification Kit (Fluorometric)
    Histone H4 (K8 acetylation) キット 製品一覧
  • 検出感度
    0.4 ng/well
  • 検出範囲
    20 ng/well - 5000 ng/well
  • 全工程の試験時間
    2h 30m
  • 種交差性
    交差種: Mouse, Human
    交差が予測される動物種: all Mammals
  • 製品の概要

    Acetylation of histones such histone H4 has been involved in the regulation of chromatin structure and the recruitment of transcription factors to gene promoters. HATs (histone acetyltransferases) and HDACs (histone deacetylases) play a critical role in controlling histone H4 actylation. Histone H4 (acetyl K8) reflects the hyperacetylated stated in histone H4 and strongly correlates with active state of genes. H4 (acetyl K8) is related to DNA repair and increased H4 (acetyl K8) has been observed in cancer and inflammatory diseases.

    Abcam's Histone H4 (acetyl K8) Quantification Kit (Fluorometric) (ab115119) allows the experimenter to measure global acetylation of histone H4K8 quickly and consistently. The kit is ready-to-use and provides all the essential components needed to carry out a successful assay experiment and it is suitable for specifically measuring global histone H4K8 acetylation using a variety of mammalian cells including fresh and frozen tissues, and cultured adherent and suspension cells.

  • アプリケーション適用あり: Functional Studiesmore details

製品の特性

    アプリケーション

    Our Abpromise guarantee covers the use of ab115119 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    アプリケーション Abreviews 特記事項
    Functional Studies Use at an assay dependent concentration.

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    Histone H4 (acetyl K8) Quantification Kit (Fluorometric) (ab115119) 使用論文

    ab115119 has not yet been referenced specifically in any publications.

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