Lu L et al.The plant-specific histone residue Phe41 is important for genome-wide H3.1 distribution.Nat Commun 9:630 (2018).
PubMed: 29434220
Moretto F et al.A regulatory circuit of two lncRNAs and a master regulator directs cell fate in yeast.Nat Commun 9:780 (2018).
PubMed: 29472539
du Mee DJM et al.Efficient termination of nuclear lncRNA transcription promotes mitochondrial genome maintenance.Elife 7:N/A (2018).
PubMed: 29504936
Bonev B et al.Multiscale 3D Genome Rewiring during Mouse Neural Development.Cell 171:557-572.e24 (2017).
Mouse
.
PubMed: 29053968
Nomura M et al.Distinct molecular profile of diffuse cerebellar gliomas.Acta Neuropathol 134:941-956 (2017).
IHC
;
Human
.
PubMed: 28852847
Jih G et al.Unique roles for histone H3K9me states in RNAi and heritable silencing of transcription.Nature 547:463-467 (2017).
ChIP
.
PubMed: 28682306
Wollmann H et al.The histone H3 variant H3.3 regulates gene body DNA methylation in Arabidopsis thaliana.Genome Biol 18:94 (2017).
PubMed: 28521766
Pajoro A et al.Histone H3 lysine 36 methylation affects temperature-induced alternative splicing and flowering in plants.Genome Biol 18:102 (2017).
PubMed: 28566089
Nanan KK et al.Independence between pre-mRNA splicing and DNA methylation in an isogenic minigene resource.Nucleic Acids Res 45:12780-12797 (2017).
PubMed: 29244186
Huang C et al.Mrg15 stimulates Ash1 H3K36 methyltransferase activity and facilitates Ash1 Trithorax group protein function in Drosophila.Nat Commun 8:1649 (2017).
PubMed: 29158494
Elurbe DM et al.Regulatory remodeling in the allo-tetraploid frog Xenopus laevis.Genome Biol 18:198 (2017).
PubMed: 29065907
Altemose N et al.A map of human PRDM9 binding provides evidence for novel behaviors of PRDM9 and other zinc-finger proteins in meiosis.Elife 6:N/A (2017).
PubMed: 29072575
Pan X et al.Chromatin states responsible for the regulation of differentially expressed genes under60Co~? ray radiation in rice.BMC Genomics 18:778 (2017).
PubMed: 29025389
Blinka S et al.Identification of Transcribed Enhancers by Genome-Wide Chromatin Immunoprecipitation Sequencing.Methods Mol Biol 1468:91-109 (2017).
PubMed: 27662872
Getun IV et al.Functional Roles of Acetylated Histone Marks at Mouse Meiotic Recombination Hot Spots.Mol Cell Biol 37:N/A (2017).
PubMed: 27821479
Dai L et al.SETD4 Regulates Cell Quiescence and Catalyzes the Trimethylation of H4K20 during Diapause Formation in Artemia.Mol Cell Biol 37:N/A (2017).
PubMed: 28031330
Luo D et al.Deltex2 represses MyoD expression and inhibits myogenic differentiation by acting as a negative regulator of Jmjd1c.Proc Natl Acad Sci U S A 114:E3071-E3080 (2017).
PubMed: 28351977
Meers MP et al.Histone gene replacement reveals a post-transcriptional role for H3K36 in maintaining metazoan transcriptome fidelity.Elife 6:N/A (2017).
PubMed: 28346137
Lai B et al.MLL3/MLL4 are required for CBP/p300 binding on enhancers and super-enhancer formation in brown adipogenesis.Nucleic Acids Res 45:6388-6403 (2017).
PubMed: 28398509
Teif VB et al.Nucleosome repositioning during differentiation of a human myeloid leukemia cell line.Nucleus 8:188-204 (2017).
PubMed: 28406749
Lee Y et al.The ATP-dependent chromatin remodeler Chd1 is recruited by transcription elongation factors and maintains H3K4me3/H3K36me3 domains at actively transcribed and spliced genes.Nucleic Acids Res 45:7180-7190 (2017).
PubMed: 28460001
Stolzenburg LR et al.Regulatory dynamics of 11p13 suggest a role for EHF in modifying CF lung disease severity.Nucleic Acids Res 45:8773-8784 (2017).
PubMed: 28549169
Calvert AE et al.Cancer-Associated IDH1 Promotes Growth and Resistance to Targeted Therapies in the Absence of Mutation.Cell Rep 19:1858-1873 (2017).
PubMed: 28564604
Li LX et al.Lysine methyltransferase SMYD2 promotes cyst growth in autosomal dominant polycystic kidney disease.J Clin Invest 127:2751-2764 (2017).
PubMed: 28604386
Kresovich JK et al.Histone 3 modifications and blood pressure in the Beijing Truck Driver Air Pollution Study.Biomarkers 22:584-593 (2017).
PubMed: 28678539
Meyer MB et al.A kidney-specific genetic control module in mice governs endocrine regulation of the cytochrome P450 geneCyp27b1essential for vitamin D3activation.J Biol Chem 292:17541-17558 (2017).
PubMed: 28808057
Jeziorska DM et al.DNA methylation of intragenic CpG islands depends on their transcriptional activity during differentiation and disease.Proc Natl Acad Sci U S A 114:E7526-E7535 (2017).
PubMed: 28827334
Shin HM et al.Transient expression of ZBTB32 in anti-viral CD8+ T cells limits the magnitude of the effector response and the generation of memory.PLoS Pathog 13:e1006544 (2017).
PubMed: 28827827
Chen J et al.VEGF amplifies transcription through ETS1 acetylation to enable angiogenesis.Nat Commun 8:383 (2017).
PubMed: 28851877
Chia M et al.Transcription of a 5' extended mRNA isoform directs dynamic chromatin changes and interference of a downstream promoter.Elife 6:N/A (2017).
PubMed: 28906248
Dobrynin G et al.KDM4A regulates HIF-1 levels through H3K9me3.Sci Rep 7:11094 (2017).
PubMed: 28894274
Zarnegar MA et al.Targeted chromatin ligation, a robust epigenetic profiling technique for small cell numbers.Nucleic Acids Res 45:e153 (2017).
PubMed: 28973448
Zhang Z et al.Crosstalk between histone modifications indicates that inhibition of arginine methyltransferase CARM1 activity reverses HIV latency.Nucleic Acids Res 45:9348-9360 (2017).
ChIP
.
PubMed: 28637181
Chronis C et al.Cooperative Binding of Transcription Factors Orchestrates Reprogramming.Cell 168:442-459.e20 (2017).
PubMed: 28111071
Molitor J et al.Retrieving Chromatin Patterns from Deep Sequencing Data Using Correlation Functions.Biophys J 112:473-490 (2017).
PubMed: 28131315
Yadav RK et al.Histone H3G34R mutation causes replication stress, homologous recombination defects and genomic instability in S. pombe.Elife 6:N/A (2017).
PubMed: 28718400
Jensen GS et al.The RNA Polymerase-Associated Factor 1 Complex Is Required for Plant Touch Responses.J Exp Bot 68:499-511 (2017).
WB
.
PubMed: 28204553
Natale F et al.Identification of the elementary structural units of the DNA damage response.Nat Commun 8:15760 (2017).
PubMed: 28604675
Battaglia S et al.RNA-dependent chromatin association of transcription elongation factors and Pol II CTD kinases.Elife 6:N/A (2017).
PubMed: 28537551
Vosnakis N et al.Coactivators and general transcription factors have two distinct dynamic populations dependent on transcription.EMBO J 36:2710-2725 (2017).
PubMed: 28724529
Janke R et al.Oncometabolite D-2-Hydroxyglutarate enhances gene silencing through inhibition of specific H3K36 histone demethylases.Elife 6:N/A (2017).
WB
;
Saccharomyces cerevisiae
.
PubMed: 28346139
Wu H et al.Chromatin dynamics regulate mesenchymal stem cell lineage specification and differentiation to osteogenesis.Biochim Biophys Acta 1860:438-449 (2017).
ChIP
.
PubMed: 28077316
Young CP et al.Distinct histone methylation and transcription profiles are established during the development of cellular quiescence in yeast.BMC Genomics 18:107 (2017).
WB, ChIP
;
Saccharomyces cerevisiae
.
PubMed: 28122508
Guitart AV et al.Fumarate hydratase is a critical metabolic regulator of hematopoietic stem cell functions.J Exp Med 214:719-735 (2017).
WB
;
Mouse
.
PubMed: 28202494
Soboleva TA et al.A new link between transcriptional initiation and pre-mRNA splicing: The RNA binding histone variant H2A.B.PLoS Genet 13:e1006633 (2017).
ChIP
;
Mouse
.
PubMed: 28234895
Flury V et al.The Histone Acetyltransferase Mst2 Protects Active Chromatin from Epigenetic Silencing by Acetylating the Ubiquitin Ligase Brl1.Mol Cell 67:294-307.e9 (2017).
ChIP
;
Schizosaccharomyces pombe
.
PubMed: 28648780
Sanders D et al.Histone Lysine-to-Methionine Mutations Reduce Histone Methylation and Cause Developmental Pleiotropy.Plant Physiol 173:2243-2252 (2017).
WB
.
PubMed: 28202597
Du Y et al.Nucleosome eviction along with H3K9ac deposition enhances Sox2 binding during human neuroectodermal commitment.Cell Death Differ 24:1121-1131 (2017).
CHIPseq
;
Human
.
PubMed: 28475175
Sayou C et al.RNA Binding by Histone Methyltransferases Set1 and Set2.Mol Cell Biol 37:N/A (2017).
WB
;
Saccharomyces cerevisiae
.
PubMed: 28483910
McDaniel SL et al.H3K36 Methylation Regulates Nutrient Stress Response in Saccharomyces cerevisiae by Enforcing Transcriptional Fidelity.Cell Rep 19:2371-2382 (2017).
Saccharomyces cerevisiae
.
PubMed: 28614721
McKnight RA et al.Intrauterine growth restriction inhibits expression of eukaryotic elongation factor 2 kinase, a regulator of protein translation.Physiol Genomics 48:616-25 (2016).
ChIP
;
Rat
.
PubMed: 27317589
Su Z et al.Reader domain specificity and lysine demethylase-4 family function.Nat Commun 7:13387 (2016).
WB
;
Mouse
.
PubMed: 27841353
Venkatesh S et al.Selective suppression of antisense transcription by Set2-mediated H3K36 methylation.Nat Commun 7:13610 (2016).
WB, ChIP
;
Saccharomyces cerevisiae
.
PubMed: 27892455
Kim JH et al.Modulation of mRNA and lncRNA expression dynamics by the Set2-Rpd3S pathway.Nat Commun 7:13534 (2016).
ChIP
;
Saccharomyces cerevisiae
.
PubMed: 27892458
Miyazato P et al.Application of targeted enrichment to next-generation sequencing of retroviruses integrated into the host human genome.Sci Rep 6:28324 (2016).
PubMed: 27321866
Li R et al.Misregulation of Alternative Splicing in a Mouse Model of Rett Syndrome.PLoS Genet 12:e1006129 (2016).
ChIP
.
PubMed: 27352031
Jones JW et al.Recruitment of Saccharomyces cerevisiae Cmr1/Ydl156w to Coding Regions Promotes Transcription Genome Wide.PLoS One 11:e0148897 (2016).
ChIP
;
Saccharomyces cerevisiae
.
PubMed: 26848854
Romanello M et al.Histone H3.3 promotes IgV gene diversification by enhancing formation of AID-accessible single-stranded DNA.EMBO J 35:1452-64 (2016).
ChIP
;
Chicken
.
PubMed: 27220848
Ahn JH et al.A Conserved Nuclear Cyclophilin Is Required for Both RNA Polymerase II Elongation and Co-transcriptional Splicing in Caenorhabditis elegans.PLoS Genet 12:e1006227 (2016).
WB
;
Caenorhabditis elegans
.
PubMed: 27541139
Yang Y et al.PAF Complex Plays Novel Subunit-Specific Roles in Alternative Cleavage and Polyadenylation.PLoS Genet 12:e1005794 (2016).
WB, ChIP
;
Mouse
.
PubMed: 26765774
Bieberstein NI et al.TALE-directed local modulation of H3K9 methylation shapes exon recognition.Sci Rep 6:29961 (2016).
ChIP
.
PubMed: 27439481
Savic D et al.Distinct gene regulatory programs define the inhibitory effects of liver X receptors and PPARG on cancer cell proliferation.Genome Med 8:74 (2016).
CHIPseq
;
Human
.
PubMed: 27401066
Meyer MB et al.Epigenetic Plasticity Drives Adipogenic and Osteogenic Differentiation of Marrow-derived Mesenchymal Stem Cells.J Biol Chem 291:17829-47 (2016).
PubMed: 27402842
Lee S et al.Global Regulation of Plant Immunity by Histone Lysine Methyl Transferases.Plant Cell 28:1640-61 (2016).
WB
;
Arabidopsis thaliana
.
PubMed: 27354553
Tamaoki K et al.Morphological, biochemical, transcriptional and epigenetic responses to fasting and refeeding in intestine of Xenopus laevis.Cell Biosci 6:2 (2016).
PubMed: 26798452
Feng J et al.ZRF1 Chromatin Regulators Have Polycomb Silencing and Independent Roles in Development.Plant Physiol 172:1746-1759 (2016).
WB
;
Arabidopsis thaliana
.
PubMed: 27630184
Mathew RS et al.A microRNA negative feedback loop downregulates vesicle transport and inhibits fear memory.Elife 5:N/A (2016).
ChIP
;
Rat
.
PubMed: 28001126
Das D et al.Anti-viral role of toll like receptor 4 in hepatitis B virus infection: An in vitro study.World J Gastroenterol 22:10341-10352 (2016).
WB
;
Human
.
PubMed: 28058014
Tan PY et al.E2F1 Orchestrates Transcriptomics and Oxidative Metabolism in Wharton's Jelly-Derived Mesenchymal Stem Cells from Growth-Restricted Infants.PLoS One 11:e0163035 (2016).
ChIP
;
Human
.
PubMed: 27631473
Natisvili T et al.Transcriptional Activation of Pericentromeric Satellite Repeats and Disruption of Centromeric Clustering upon Proteasome Inhibition.PLoS One 11:e0165873 (2016).
ChIP
;
Mouse
.
PubMed: 27806100
Ni T et al.Global intron retention mediated gene regulation during CD4+ T cell activation.Nucleic Acids Res 44:6817-29 (2016).
ChIP
;
Human
.
PubMed: 27369383
Hunter GO et al.Phosphatase Rtr1 Regulates Global Levels of Serine 5 RNA Polymerase II C-Terminal Domain Phosphorylation and Cotranscriptional Histone Methylation.Mol Cell Biol 36:2236-45 (2016).
PubMed: 27247267
Hacker KE et al.Structure/Function Analysis of Recurrent Mutations in SETD2 Protein Reveals a Critical and Conserved Role for a SET Domain Residue in Maintaining Protein Stability and Histone H3 Lys-36 Trimethylation.J Biol Chem 291:21283-21295 (2016).
PubMed: 27528607
Wu Z et al.
Quantitative regulation of FLC via coordinated transcriptional initiation and elongation.
Proc Natl Acad Sci U S A 113:218-23 (2016).
ChIP
.
PubMed: 26699513
Liu B et al.SET DOMAIN GROUP 708, a histone H3 lysine 36-specific methyltransferase, controls flowering time in rice (Oryza sativa).New Phytol 210:577-88 (2016).
ChIP
;
Rice
.
PubMed: 26639303
Gacek-Matthews A et al.KdmB, a Jumonji Histone H3 Demethylase, Regulates Genome-Wide H3K4 Trimethylation and Is Required for Normal Induction of Secondary Metabolism in Aspergillus nidulans.PLoS Genet 12:e1006222 (2016).
WB
.
PubMed: 27548260
Elnfati AH et al.Nucleosomal chromatin in the mature sperm of Drosophila melanogaster.Genom Data 7:175-7 (2016).
PubMed: 26981400
Kim TD et al.ETS transcription factor ERG cooperates with histone demethylase KDM4A.Oncol Rep 35:3679-88 (2016).
ChIP
.
PubMed: 27109047
Li D et al.Profiling Analysis of Histone Modifications and Gene Expression in Lewis Lung Carcinoma Murine Cells Resistant to Anti-VEGF Treatment.PLoS One 11:e0158214 (2016).
ChIP
.
PubMed: 27362259
Kotzin JJ et al.The long non-coding RNA Morrbid regulates Bim and short-lived myeloid cell lifespan.Nature 537:239-243 (2016).
CHIPseq
.
PubMed: 27525555
Guryanova OA et al.DNMT3A mutations promote anthracycline resistance in acute myeloid leukemia via impaired nucleosome remodeling.Nat Med 22:1488-1495 (2016).
PubMed: 27841873
Adhikary S et al.Selective Recognition of H3.1K36 Dimethylation/H4K16 Acetylation Facilitates the Regulation of All-trans-retinoic Acid (ATRA)-responsive Genes by Putative Chromatin Reader ZMYND8.J Biol Chem 291:2664-81 (2016).
PubMed: 26655721
Richarson AD et al.Registered report: IDH mutation impairs histone demethylation and results in a block to cell differentiation.Elife 5:e10860 (2016).
PubMed: 26971564
Liu Y & Zhang D HP1a/KDM4A is involved in the autoregulatory loop of the oncogene gene c-Jun.Epigenetics 10:453-9 (2015).
PubMed: 25945750
Li D et al.Epigenetic regulation of traf2- and Nck-interacting kinase (TNIK) in polycystic ovary syndrome.Am J Transl Res 7:1152-60 (2015).
PubMed: 26279758
Nag A et al.Chromatin Signature Identifies Monoallelic Gene Expression Across Mammalian Cell Types.G3 (Bethesda) 5:1713-20 (2015).
ChIP
.
PubMed: 26092837
Takahashi JS et al.ChIP-seq and RNA-seq methods to study circadian control of transcription in mammals.Methods Enzymol 551:285-321 (2015).
PubMed: 25662462
Lu S et al.The transcription factor c-Fos coordinates with histone lysine-specific demethylase 2A to activate the expression of cyclooxygenase-2.Oncotarget 6:34704-17 (2015).
WB
.
PubMed: 26430963
Reeder JE et al.HIV Tat controls RNA Polymerase II and the epigenetic landscape to transcriptionally reprogram target immune cells.Elife 4:N/A (2015).
ChIP
.
PubMed: 26488441
Bercht Pfleghaar K et al.Gene-rich chromosomal regions are preferentially localized in the lamin B deficient nuclear blebs of atypical progeria cells.Nucleus 6:66-76 (2015).
PubMed: 25738644
Kang S et al.Identification of nuclear hormone receptor pathways causing insulin resistance by transcriptional and epigenomic analysis.Nat Cell Biol 17:44-56 (2015).
PubMed: 25503565
Wallace HA et al.Condensin II Regulates Interphase Chromatin Organization Through the Mrg-Binding Motif of Cap-H2.G3 (Bethesda) 5:803-17 (2015).
PubMed: 25758823
Liu W et al.Decreased Expression of SETD2 Predicts Unfavorable Prognosis in Patients With Nonmetastatic Clear-Cell Renal Cell Carcinoma.Medicine (Baltimore) 94:e2004 (2015).
IHC
.
PubMed: 26559293
Park JL et al.Decrease of 5hmC in gastric cancers is associated with TET1 silencing due to with DNA methylation and bivalent histone marks at TET1 CpG island 3'-shore.Oncotarget 6:37647-62 (2015).
ChIP
.
PubMed: 26462176
Xiang W et al.miR-106b-5p targets tumor suppressor gene SETD2 to inactive its function in clear cell renal cell carcinoma.Oncotarget 6:4066-79 (2015).
WB
.
PubMed: 25714014
Stubbs SH & Conrad NK Depletion of REF/Aly alters gene expression and reduces RNA polymerase II occupancy.Nucleic Acids Res 43:504-19 (2015).
PubMed: 25477387
Saloura V et al.WHSC1 promotes oncogenesis through regulation of NIMA-related kinase-7 in squamous cell carcinoma of the head and neck.Mol Cancer Res 13:293-304 (2015).
WB
;
Human
.
PubMed: 25280969
Lee J et al.
A methyltransferase required for proper timing of the vernalization response in Arabidopsis.
Proc Natl Acad Sci U S A 112:2269-74 (2015).
WB
;
Arabidopsis thaliana
.
PubMed: 25605879
Li P et al.
Phenotypic evolution through variation in splicing of the noncoding RNA COOLAIR.
Genes Dev 29:696-701 (2015).
ChIP
.
PubMed: 25805848
Kelly S et al.
Splicing of many human genes involves sites embedded within introns.
Nucleic Acids Res 43:4721-32 (2015).
ChIP
;
Human
.
PubMed: 25897131
Cucinotta CE et al.
The Nucleosome Acidic Patch Regulates the H2B K123 Monoubiquitylation Cascade and Transcription Elongation in Saccharomyces cerevisiae.
PLoS Genet 11:e1005420 (2015).
WB
.
PubMed: 26241481
Mbogning J et al.
Functional interaction of Rpb1 and Spt5 C-terminal domains in co-transcriptional histone modification.
Nucleic Acids Res 43:9766-75 (2015).
WB
;
Schizosaccharomyces pombe
.
PubMed: 26275777
Hou Y et al.
JMJ704 positively regulates rice defense response against Xanthomonas oryzae pv. oryzae infection via reducing H3K4me2/3 associated with negative disease resistance regulators.
BMC Plant Biol 15:286 (2015).
WB
;
Rice
.
PubMed: 26646110
Rathert P et al.Transcriptional plasticity promotes primary and acquired resistance to BET inhibition.Nature 525:543-7 (2015).
PubMed: 26367798
Carey BW et al.Intracellular a-ketoglutarate maintains the pluripotency of embryonic stem cells.Nature 518:413-6 (2015).
WB
;
Mouse
.
PubMed: 25487152
Duncan EM et al.Set1 and MLL1/2 Target Distinct Sets of Functionally Different Genomic Loci In Vivo.Cell Rep 13:2741-55 (2015).
ChIP
;
Schmidtea mediterranea
.
PubMed: 26711341
Hodges AJ et al.Histone Sprocket Arginine Residues Are Important for Gene Expression, DNA Repair, and Cell Viability in Saccharomyces cerevisiae.Genetics 200:795-806 (2015).
WB
.
PubMed: 25971662
Krivega I et al.Inhibition of G9a methyltransferase stimulates fetal hemoglobin production by facilitating LCR/?-globin looping.Blood 126:665-72 (2015).
ChIP
.
PubMed: 25979948
Preissl S et al.Deciphering the Epigenetic Code of Cardiac Myocyte Transcription.Circ Res 117:413-23 (2015).
ChIP
.
PubMed: 26105955
Alekseyenko AA et al.The oncogenic BRD4-NUT chromatin regulator drives aberrant transcription within large topological domains.Genes Dev 29:1507-23 (2015).
ChIP
;
Human
.
PubMed: 26220994
Ohhata T et al.Histone H3 Lysine 36 Trimethylation Is Established over the Xist Promoter by Antisense Tsix Transcription and Contributes to Repressing Xist Expression.Mol Cell Biol 35:3909-20 (2015).
WB, ChIP
.
PubMed: 26370508
Li Y et al.
Arginine Methyltransferase 1 in the Nucleus Accumbens Regulates Behavioral Effects of Cocaine.
J Neurosci 35:12890-902 (2015).
WB
;
Mouse
.
PubMed: 26377474
Masuda Y et al.TRIM29 regulates the assembly of DNA repair proteins into damaged chromatin.Nat Commun 6:7299 (2015).
Human
.
PubMed: 26095369
Ji X et al.Chromatin proteomic profiling reveals novel proteins associated with histone-marked genomic regions.Proc Natl Acad Sci U S A 112:3841-6 (2015).
WB, ChIP, CHIPseq
;
Mouse
.
PubMed: 25755260
Sharma G et al.The interaction of mycobacterial protein Rv2966c with host chromatin is mediated through non-CpG methylation and histone H3/H4 binding.Nucleic Acids Res 43:3922-37 (2015).
WB
;
Human
.
PubMed: 25824946
Pu M et al.Trimethylation of Lys36 on H3 restricts gene expression change during aging and impacts life span.Genes Dev 29:718-31 (2015).
ChIP
;
Caenorhabditis elegans
.
PubMed: 25838541
Kim HJ et al.Identification of a new selective chemical inhibitor of mutant isocitrate dehydrogenase-1.J Cancer Prev 20:78-83 (2015).
WB
;
Human
.
PubMed: 25853107
Jin J et al.MORF-RELATED GENE702, a Reader Protein of Trimethylated Histone H3 Lysine 4 and Histone H3 Lysine 36, Is Involved in Brassinosteroid-Regulated Growth and Flowering Time Control in Rice.Plant Physiol 168:1275-85 (2015).
ChIP, Dot blot, ICC/IF
;
Rice
.
PubMed: 25855537
Guo Z et al.Global epigenomic analysis indicates that epialleles contribute to Allele-specific expression via Allele-specific histone modifications in hybrid rice.BMC Genomics 16:232 (2015).
CHIPseq
;
Rice
.
PubMed: 25886904
Engel KL et al.Spt6 Is Essential for rRNA Synthesis by RNA Polymerase I.Mol Cell Biol 35:2321-31 (2015).
ChIP
;
Saccharomyces cerevisiae
.
PubMed: 25918242
Kowalik KM et al.The Paf1 complex represses small-RNA-mediated epigenetic gene silencing.Nature 520:248-252 (2015).
ChIP
;
Schizosaccharomyces pombe
.
PubMed: 25807481
Chen CW et al.DOT1L inhibits SIRT1-mediated epigenetic silencing to maintain leukemic gene expression in MLL-rearranged leukemia.Nat Med 21:335-43 (2015).
PubMed: 25822366
Zhu J et al.Gain-of-function p53 mutants co-opt chromatin pathways to drive cancer growth.Nature 525:206-11 (2015).
WB
;
Human
.
PubMed: 26331536
Hontelez S et al.Embryonic transcription is controlled by maternally defined chromatin state.Nat Commun 6:10148 (2015).
ChIP
;
Xenopus tropicalis
.
PubMed: 26679111
Wong SH et al.The H3K4-Methyl Epigenome Regulates Leukemia Stem Cell Oncogenic Potential.Cancer Cell 28:198-209 (2015).
ChIP
;
Mouse, Human
.
PubMed: 26190263
Pérez-Lluch S et al.Absence of canonical marks of active chromatin in developmentally regulated genes.Nat Genet 47:1158-1167 (2015).
ChIP
;
Drosophila melanogaster
.
PubMed: 26280901
Yao X et al.The Mediator subunit MED23 couples H2B mono-ubiquitination to transcriptional control and cell fate determination.EMBO J 34:2885-902 (2015).
WB
.
PubMed: 26330467
Biagioli M et al.Htt CAG repeat expansion confers pleiotropic gains of mutant huntingtin function in chromatin regulation.Hum Mol Genet 24:2442-57 (2015).
ChIP
;
Mouse
.
PubMed: 25574027
Koo JW et al.Epigenetic basis of opiate suppression of Bdnf gene expression in the ventral tegmental area.Nat Neurosci 18:415-22 (2015).
ChIP
;
Rat
.
PubMed: 25643298
Gjoneska E et al.Conserved epigenomic signals in mice and humans reveal immune basis of Alzheimer's disease.Nature 518:365-9 (2015).
ChIP
;
Mouse
.
PubMed: 25693568
Kanu N et al.SETD2 loss-of-function promotes renal cancer branched evolution through replication stress and impaired DNA repair.Oncogene 34:5699-708 (2015).
WB, IHC-P, ChIP
;
Human
.
PubMed: 25728682
Morselli M et al.In vivo targeting of de novo DNA methylation by histone modifications in yeast and mouse.Elife 4:e06205 (2015).
ChIP
.
PubMed: 25848745
Rothbart SB et al.An Interactive Database for the Assessment of Histone Antibody Specificity.Mol Cell 59:502-11 (2015).
PubMed: 26212453
Ferrari P & Strubin M Uncoupling histone turnover from transcription-associated histone H3 modifications.Nucleic Acids Res 43:3972-85 (2015).
ChIP
;
Saccharomyces cerevisiae
.
PubMed: 25845593
Wang Y et al.Balancing acts of SRI and an auto-inhibitory domain specify Set2 function at transcribed chromatin.Nucleic Acids Res 43:4881-92 (2015).
WB, ChIP
;
Saccharomyces cerevisiae
.
PubMed: 25925577
Maekawa S et al.Analysis of RNA decay factor mediated RNA stability contributions on RNA abundance.BMC Genomics 16:154 (2015).
ChIP
;
Human
.
PubMed: 25879614
Liu X et al.The rice enhancer of zeste [E(z)] genes SDG711 and SDG718 are respectively involved in long day and short day signaling to mediate the accurate photoperiod control of flowering time.Front Plant Sci 5:591 (2014).
WB
.
PubMed: 25400654
Magraner-Pardo L et al.Dynamic remodeling of histone modifications in response to osmotic stress in Saccharomyces cerevisiae.BMC Genomics 15:247 (2014).
ChIP
.
PubMed: 24678875
Park D et al.Chd1 co-localizes with early transcription elongation factors independently of H3K36 methylation and releases stalled RNA polymerase II at introns.Epigenetics Chromatin 7:32 (2014).
WB
.
PubMed: 25395991
Walsh CA et al.Global gene repression by the steroid receptor coactivator SRC-1 promotes oncogenesis.Cancer Res 74:2533-44 (2014).
PubMed: 24648347
Aguilar R et al.A functional N-terminal domain in C/EBPß-LAP* is required for interacting with SWI/SNF and to repress Ric-8B gene transcription in osteoblasts.J Cell Physiol 229:1521-8 (2014).
PubMed: 24585571
Gan ES et al.Jumonji demethylases moderate precocious flowering at elevated temperature via regulation of FLC in Arabidopsis.Nat Commun 5:5098 (2014).
PubMed: 25267112
Hérissant L et al.H2B ubiquitylation modulates spliceosome assembly and function in budding yeast.Biol Cell 106:126-38 (2014).
ChIP
.
PubMed: 24476359
Hackermüller J et al.Cell cycle, oncogenic and tumor suppressor pathways regulate numerous long and macro non-protein-coding RNAs.Genome Biol 15:R48 (2014).
ChIP
;
Human
.
PubMed: 24594072
Descostes N et al.Tyrosine phosphorylation of RNA polymerase II CTD is associated with antisense promoter transcription and active enhancers in mammalian cells.Elife 3:e02105 (2014).
ChIP
;
Human
.
PubMed: 24842994
Li T & Kelly WG A role for WDR5 in TRA-1/Gli mediated transcriptional control of the sperm/oocyte switch in C. elegans.Nucleic Acids Res 42:5567-81 (2014).
ChIP
;
Human
.
PubMed: 24682813
Knoechel B et al.An epigenetic mechanism of resistance to targeted therapy in T cell acute lymphoblastic leukemia.Nat Genet 46:364-70 (2014).
ChIP
;
Human
.
PubMed: 24584072
Kumar RM et al.Deconstructing transcriptional heterogeneity in pluripotent stem cells.Nature 516:56-61 (2014).
PubMed: 25471879
Creppe C et al.A Cbx8-containing polycomb complex facilitates the transition to gene activation during ES cell differentiation.PLoS Genet 10:e1004851 (2014).
PubMed: 25500566
Schiavone D et al.Determinants of G quadruplex-induced epigenetic instability in REV1-deficient cells.EMBO J 33:2507-20 (2014).
PubMed: 25190518
Gilbert TM et al.A PWWP domain-containing protein targets the NuA3 acetyltransferase complex via histone H3 lysine 36 trimethylation to coordinate transcriptional elongation at coding regions.Mol Cell Proteomics 13:2883-95 (2014).
PubMed: 25104842
Kungulovski G et al.Application of histone modification-specific interaction domains as an alternative to antibodies.Genome Res 24:1842-53 (2014).
PubMed: 25301795
Csorba T et al.Antisense COOLAIR mediates the coordinated switching of chromatin states at FLC during vernalization.Proc Natl Acad Sci U S A 111:16160-5 (2014).
ChIP
.
PubMed: 25349421
Sharma A et al.Calcium-mediated histone modifications regulate alternative splicing in cardiomyocytes.Proc Natl Acad Sci U S A 111:E4920-8 (2014).
PubMed: 25368158
Suzuki A et al.Aberrant transcriptional regulations in cancers: genome, transcriptome and epigenome analysis of lung adenocarcinoma cell lines.Nucleic Acids Res 42:13557-72 (2014).
CHIPseq
;
Human
.
PubMed: 25378332
Ginsburg DS et al.NuA4 links methylation of histone H3 lysines 4 and 36 to acetylation of histones H4 and H3.J Biol Chem 289:32656-70 (2014).
PubMed: 25301943
Veerappan V et al.HSI2/VAL1 PHD-like domain promotes H3K27 trimethylation to repress the expression of seed maturation genes and complex transgenes in Arabidopsis seedlings.BMC Plant Biol 14:293 (2014).
ChIP
;
Plants
.
PubMed: 25367506
Chakravarty D et al.The oestrogen receptor alpha-regulated lncRNA NEAT1 is a critical modulator of prostate cancer.Nat Commun 5:5383 (2014).
ChIP
;
Human
.
PubMed: 25415230
Zheng Y et al.A developmental genetic analysis of the lysine demethylase KDM2 mutations in Drosophila melanogaster.Mech Dev 133:36-53 (2014).
WB
;
Drosophila melanogaster
.
PubMed: 25016215
Bu Z et al.Regulation of arabidopsis flowering by the histone mark readers MRG1/2 via interaction with CONSTANS to modulate FT expression.PLoS Genet 10:e1004617 (2014).
ChIP, Dot blot
;
Arabidopsis thaliana
.
PubMed: 25211338
Crevillén P et al.Epigenetic reprogramming that prevents transgenerational inheritance of the vernalized state.Nature N/A:N/A (2014).
PubMed: 25219852
Popovic R et al.Histone methyltransferase MMSET/NSD2 alters EZH2 binding and reprograms the myeloma epigenome through global and focal changes in H3K36 and H3K27 methylation.PLoS Genet 10:e1004566 (2014).
ChIP
;
Human
.
PubMed: 25188243
Lee YF et al.Histone H3 lysine 36 methyltransferase Whsc1 promotes the association of Runx2 and p300 in the activation of bone-related genes.PLoS One 9:e106661 (2014).
ChIP
;
Mouse
.
PubMed: 25188294
Bonnet J et al.The SAGA coactivator complex acts on the whole transcribed genome and is required for RNA polymerase II transcription.Genes Dev 28:1999-2012 (2014).
PubMed: 25228644
Fuchs G et al.Cotranscriptional histone H2B monoubiquitylation is tightly coupled with RNA polymerase II elongation rate.Genome Res 24:1572-83 (2014).
PubMed: 25049226
Xu Y et al.Arabidopsis MRG domain proteins bridge two histone modifications to elevate expression of flowering genes.Nucleic Acids Res 42:10960-74 (2014).
PubMed: 25183522
Marcinkiewicz KM & Gudas LJ Altered histone mark deposition and DNA methylation at homeobox genes in human oral squamous cell carcinoma.J Cell Physiol 229:1405-16 (2014).
PubMed: 24519855
Yun WJ et al.The hematopoietic regulator TAL1 is required for chromatin looping between the ß-globin LCR and human ?-globin genes to activate transcription.Nucleic Acids Res 42:4283-93 (2014).
ChIP
;
Human
.
PubMed: 24470145
Fowler T et al.Regulation of MYC expression and differential JQ1 sensitivity in cancer cells.PLoS One 9:e87003 (2014).
ChIP
.
PubMed: 24466310
Simon JM et al.Variation in chromatin accessibility in human kidney cancer links H3K36 methyltransferase loss with widespread RNA processing defects.Genome Res 24:241-50 (2014).
Human
.
PubMed: 24158655
Zhang Y et al.Canonical nucleosome organization at promoters forms during genome activation.Genome Res 24:260-6 (2014).
Zebrafish
.
PubMed: 24285721
Looney TJ et al.Systematic mapping of occluded genes by cell fusion reveals prevalence and stability of cis-mediated silencing in somatic cells.Genome Res 24:267-80 (2014).
ChIP
.
PubMed: 24310002
Akbay EA et al.D-2-hydroxyglutarate produced by mutant IDH2 causes cardiomyopathy and neurodegeneration in mice.Genes Dev 28:479-90 (2014).
WB
.
PubMed: 24589777
Pedersen MT et al.The demethylase JMJD2C localizes to H3K4me3-positive transcription start sites and is dispensable for embryonic development.Mol Cell Biol 34:1031-45 (2014).
PubMed: 24396064
Convertini P et al.Sudemycin E influences alternative splicing and changes chromatin modifications.Nucleic Acids Res 42:4947-61 (2014).
ChIP
;
Human
.
PubMed: 24623796
Yukawa M et al.Genome-wide analysis of the chromatin composition of histone H2A and H3 variants in mouse embryonic stem cells.PLoS One 9:e92689 (2014).
ChIP
;
Mouse
.
PubMed: 24658136
Suzuki MG et al.Effects of RNAi-mediated knockdown of histone methyltransferases on the sex-specific mRNA expression of Imp in the silkworm Bombyx mori.Int J Mol Sci 15:6772-96 (2014).
ChIP
;
Silk worm
.
PubMed: 24758924
Kupershmit I et al.KDM4C (GASC1) lysine demethylase is associated with mitotic chromatin and regulates chromosome segregation during mitosis.Nucleic Acids Res 42:6168-82 (2014).
WB
;
Human
.
PubMed: 24728997
Zhang H et al.Uncoupling transcription from covalent histone modification.PLoS Genet 10:e1004202 (2014).
ChIP
.
PubMed: 24722509
Long L et al.The U4/U6 recycling factor SART3 has histone chaperone activity and associates with USP15 to regulate H2B deubiquitination.J Biol Chem 289:8916-30 (2014).
PubMed: 24526689
Fonseca GJ et al.Adenovirus E1A recruits the human Paf1 complex to enhance transcriptional elongation.J Virol 88:5630-7 (2014).
Human
.
PubMed: 24600005
Carvalho S et al.SETD2 is required for DNA double-strand break repair and activation of the p53-mediated checkpoint.Elife 3:e02482 (2014).
WB, ChIP
;
Human
.
PubMed: 24843002
Pai CC et al.A histone H3K36 chromatin switch coordinates DNA double-strand break repair pathway choice.Nat Commun 5:4091 (2014).
WB
.
PubMed: 24909977
Cooper S et al.Targeting Polycomb to Pericentric Heterochromatin in Embryonic Stem Cells Reveals a Role for H2AK119u1 in PRC2 Recruitment.Cell Rep 7:1456-70 (2014).
CHIPseq
;
Human
.
PubMed: 24857660
Rossetto D et al.Eaf5/7/3 form a functionally independent NuA4 submodule linked to RNA polymerase II-coupled nucleosome recycling.EMBO J 33:1397-415 (2014).
PubMed: 24843044
Mercier A et al.Site-Specific Association with Host and Viral Chromatin by Kaposi's Sarcoma-Associated Herpesvirus LANA and Its Reversal during Lytic Reactivation.J Virol 88:6762-6777 (2014).
PubMed: 24696474
Pfister SX et al.SETD2-Dependent Histone H3K36 Trimethylation Is Required for Homologous Recombination Repair and Genome Stability.Cell Rep 7:2006-18 (2014).
ChIP, ICC/IF, WB, IP
;
Human
.
PubMed: 24931610
Lhoumaud P et al.Insulators recruit histone methyltransferase dMes4 to regulate chromatin of flanking genes.EMBO J 33:1599-613 (2014).
PubMed: 24916307
Meyer MB et al.The RUNX2 Cistrome in Osteoblasts: CHARACTERIZATION, DOWN-REGULATION FOLLOWING DIFFERENTIATION, AND RELATIONSHIP TO GENE EXPRESSION.J Biol Chem 289:16016-16031 (2014).
ChIP
;
Mouse
.
PubMed: 24764292
Yang X et al.Histone modifications are associated with ?9-tetrahydrocannabinol-mediated alterations in antigen-specific T cell responses.J Biol Chem 289:18707-18 (2014).
ChIP
;
Mouse
.
PubMed: 24841204
Meyer MB et al.Genomic determinants of gene regulation by 1,25-dihydroxyvitamin D3 during osteoblast-lineage cell differentiation.J Biol Chem 289:19539-54 (2014).
Mouse
.
PubMed: 24891508
Tarrio ML et al.Proliferation conditions promote intrinsic changes in NK cells for an IL-10 response.J Immunol 193:354-63 (2014).
PubMed: 24907347
Lee SM et al.HBx induces hypomethylation of distal intragenic CpG islands required for active expression of developmental regulators.Proc Natl Acad Sci U S A 111:9555-60 (2014).
Mouse
.
PubMed: 24941955
da Glória VG et al.T cell activation regulates CD6 alternative splicing by transcription dynamics and SRSF1.J Immunol 193:391-9 (2014).
Human
.
PubMed: 24890719
Matsumoto K et al.Construction of mate pair full-length cDNAs libraries and characterization of transcriptional start sites and termination sites.Nucleic Acids Res N/A:N/A (2014).
CHIPseq
;
Human
.
PubMed: 25034687
Wang X et al.Histone lysine methyltransferase SDG8 is involved in brassinosteroid-regulated gene expression in Arabidopsis thaliana.Mol Plant 7:1303-15 (2014).
PubMed: 24838002
Hou X et al.Nuclear factor Y-mediated H3K27me3 demethylation of the SOC1 locus orchestrates flowering responses of Arabidopsis.Nat Commun 5:4601 (2014).
Arabidopsis thaliana
.
PubMed: 25105952
Kuang Z et al.High-temporal-resolution view of transcription and chromatin states across distinct metabolic states in budding yeast.Nat Struct Mol Biol N/A:N/A (2014).
Saccharomyces cerevisiae
.
PubMed: 25173176
Xue Z et al.Transcriptional interference by antisense RNA is required for circadian clock function.Nature N/A:N/A (2014).
PubMed: 25132551
Li XY et al.Establishment of regions of genomic activity during the Drosophila maternal to zygotic transition.Elife 3:N/A (2014).
ChIP
.
PubMed: 25313869
Cascante A et al.Gene-specific methylation control of H3K9 and H3K36 on neurotrophic BDNF versus astroglial GFAP genes by KDM4A/C regulates neural stem cell differentiation.J Mol Biol 426:3467-77 (2014).
PubMed: 24747049
St John HC et al.The osteoblast to osteocyte transition: epigenetic changes and response to the vitamin D3 hormone.Mol Endocrinol 28:1150-65 (2014).
PubMed: 24877565
Aymard F et al.Transcriptionally active chromatin recruits homologous recombination at DNA double-strand breaks.Nat Struct Mol Biol 21:366-74 (2014).
ChIP
.
PubMed: 24658350
Jha DK & Strahl BD An RNA polymerase II-coupled function for histone H3K36 methylation in checkpoint activation and DSB repair.Nat Commun 5:3965 (2014).
ChIP
.
PubMed: 24910128
Kryczek I et al.IL-22(+)CD4(+) T cells promote colorectal cancer stemness via STAT3 transcription factor activation and induction of the methyltransferase DOT1L.Immunity 40:772-784 (2014).
PubMed: 24816405
Cecere G et al.Global effects of the CSR-1 RNA interference pathway on the transcriptional landscape.Nat Struct Mol Biol 21:358-65 (2014).
ChIP
.
PubMed: 24681887
Light N et al.Interrogation of allelic chromatin states in human cells by high-density ChIP-genotyping.Epigenetics 9:1238-51 (2014).
PubMed: 25055051
Mikula M et al.Obesity increases histone H3 lysine 9 and 18 acetylation at Tnfa and Ccl2 genes in mouse liver.Int J Mol Med 34:1647-54 (2014).
PubMed: 25319795
Hon GC et al.5mC oxidation by Tet2 modulates enhancer activity and timing of transcriptome reprogramming during differentiation.Mol Cell 56:286-97 (2014).
PubMed: 25263596
Kurachi M et al.The transcription factor BATF operates as an essential differentiation checkpoint in early effector CD8+ T cells.Nat Immunol 15:373-83 (2014).
ChIP
.
PubMed: 24584090
Zhu X et al.Identification of functional cooperative mutations of SETD2 in human acute leukemia.Nat Genet 46:287-93 (2014).
PubMed: 24509477
Song G et al.The phenotypic predisposition of the parent in F1 hybrid is correlated with transcriptome preference of the positive general combining ability parent.BMC Genomics 15:297 (2014).
ChIP
.
PubMed: 24755044
Muratani M et al.Nanoscale chromatin profiling of gastric adenocarcinoma reveals cancer-associated cryptic promoters and somatically acquired regulatory elements.Nat Commun 5:4361 (2014).
PubMed: 25008978
Wen H et al.ZMYND11 links histone H3.3K36me3 to transcription elongation and tumour suppression.Nature 508:263-8 (2014).
PubMed: 24590075
Connolly LR et al.The Fusarium graminearum histone H3 K27 methyltransferase KMT6 regulates development and expression of secondary metabolite gene clusters.PLoS Genet 9:e1003916 (2013).
WB
.
PubMed: 24204317
Zhang K et al.CTR9/PAF1c regulates molecular lineage identity, histone H3K36 trimethylation and genomic imprinting during preimplantation development.Dev Biol 383:15-27 (2013).
PubMed: 24036311
Bjerke L et al.Histone H3.3. mutations drive pediatric glioblastoma through upregulation of MYCN.Cancer Discov 3:512-9 (2013).
PubMed: 23539269
Alekseyenko AA et al.Conservation and de novo acquisition of dosage compensation on newly evolved sex chromosomes in Drosophila.Genes Dev 27:853-8 (2013).
PubMed: 23630075
Kim W et al.Targeted disruption of the EZH2-EED complex inhibits EZH2-dependent cancer.Nat Chem Biol 9:643-50 (2013).
WB
.
PubMed: 23974116
Crona F et al.Gene regulation by the lysine demethylase KDM4A in Drosophila.Dev Biol 373:453-63 (2013).
PubMed: 23195220
Li T et al.Jumonji C domain protein JMJ705-mediated removal of histone H3 lysine 27 trimethylation is involved in defense-related gene activation in rice.Plant Cell 25:4725-36 (2013).
PubMed: 24280387
Valin A et al.Transcription factor Sp3 represses expression of p21CIP¹ via inhibition of productive elongation by RNA polymerase II.Mol Cell Biol 33:1582-93 (2013).
PubMed: 23401853
Wu F & Yao J Spatial compartmentalization at the nuclear periphery characterized by genome-wide mapping.BMC Genomics 14:591 (2013).
PubMed: 23987233
Chen M et al.Decoupling epigenetic and genetic effects through systematic analysis of gene position.Cell Rep 3:128-37 (2013).
ChIP
.
PubMed: 23291096
Sugathan A & Waxman DJ Genome-wide analysis of chromatin states reveals distinct mechanisms of sex-dependent gene regulation in male and female mouse liver.Mol Cell Biol 33:3594-610 (2013).
PubMed: 23836885
Carvalho S et al.Histone methyltransferase SETD2 coordinates FACT recruitment with nucleosome dynamics during transcription.Nucleic Acids Res 41:2881-93 (2013).
WB, IP, ChIP
.
PubMed: 23325844
Williams A et al.Hypersensitive site 6 of the Th2 locus control region is essential for Th2 cytokine expression.Proc Natl Acad Sci U S A 110:6955-60 (2013).
ChIP
.
PubMed: 23569250
Chen Q et al.Structural basis of a histone H3 lysine 4 demethylase required for stem elongation in rice.PLoS Genet 9:e1003239 (2013).
PubMed: 23357881
Fowler T et al.Regulation of primary response genes in B cells.J Biol Chem 288:14906-16 (2013).
ChIP
;
Mouse
.
PubMed: 23536186
Jack AP et al.H3K56me3 is a novel, conserved heterochromatic mark that largely but not completely overlaps with H3K9me3 in both regulation and localization.PLoS One 8:e51765 (2013).
WB
.
PubMed: 23451023
Hahn MA et al.Dynamics of 5-hydroxymethylcytosine and chromatin marks in Mammalian neurogenesis.Cell Rep 3:291-300 (2013).
ChIP
.
PubMed: 23403289
Ho LL et al.DOT1L-mediated H3K79 methylation in chromatin is dispensable for Wnt pathway-specific and other intestinal epithelial functions.Mol Cell Biol 33:1735-45 (2013).
WB
;
Mouse
.
PubMed: 23428873
Suzuki J et al.A novel small compound SH-2251 suppresses Th2 cell-dependent airway inflammation through selective modulation of chromatin status at the Il5 gene locus.PLoS One 8:e61785 (2013).
ChIP
.
PubMed: 23613936
Dreidax D et al.Low p14ARF expression in neuroblastoma cells is associated with repressed histone mark status, and enforced expression induces growth arrest and apoptosis.Hum Mol Genet 22:1735-45 (2013).
Human
.
PubMed: 23343716
van Nuland R et al.Nucleosomal DNA binding drives the recognition of H3K36-methylated nucleosomes by the PSIP1-PWWP domain.Epigenetics Chromatin 6:12 (2013).
PubMed: 23656834
Fontebasso AM et al.Mutations in SETD2 and genes affecting histone H3K36 methylation target hemispheric high-grade gliomas.Acta Neuropathol 125:659-69 (2013).
WB
.
PubMed: 23417712
Michaud J et al.HCFC1 is a common component of active human CpG-island promoters and coincides with ZNF143, THAP11, YY1, and GABP transcription factor occupancy.Genome Res 23:907-16 (2013).
PubMed: 23539139
Young LC et al.Kdm4b histone demethylase is a DNA damage response protein and confers a survival advantage following ?-irradiation.J Biol Chem 288:21376-88 (2013).
PubMed: 23744078
Eun B et al.The Igf2/H19 muscle enhancer is an active transcriptional complex.Nucleic Acids Res 41:8126-34 (2013).
PubMed: 23842673
Hatzi K et al.A hybrid mechanism of action for BCL6 in B cells defined by formation of functionally distinct complexes at enhancers and promoters.Cell Rep 4:578-88 (2013).
ChIP
.
PubMed: 23911289
Lodrini M et al.MYCN and HDAC2 cooperate to repress miR-183 signaling in neuroblastoma.Nucleic Acids Res 41:6018-33 (2013).
ChIP
.
PubMed: 23625969
Wang D et al.MicroRNA-205 controls neonatal expansion of skin stem cells by modulating the PI(3)K pathway.Nat Cell Biol 15:1153-63 (2013).
PubMed: 23974039
Sarai N et al.WHSC1 links transcription elongation to HIRA-mediated histone H3.3 deposition.EMBO J 32:2392-406 (2013).
PubMed: 23921552
Aristizabal MJ et al.High-throughput genetic and gene expression analysis of the RNAPII-CTD reveals unexpected connections to SRB10/CDK8.PLoS Genet 9:e1003758 (2013).
ChIP/Chip
.
PubMed: 24009531
Lu C et al.Induction of sarcomas by mutant IDH2.Genes Dev 27:1986-98 (2013).
PubMed: 24065766
Cie Lik M et al.Epigenetic coordination of signaling pathways during the epithelial-mesenchymal transition.Epigenetics Chromatin 6:28 (2013).
CHIPseq
.
PubMed: 24004852
Jaffe JD et al.Global chromatin profiling reveals NSD2 mutations in pediatric acute lymphoblastic leukemia.Nat Genet 45:1386-91 (2013).
PubMed: 24076604
Ding L et al.FLOWERING LOCUS C EXPRESSOR family proteins regulate FLOWERING LOCUS C expression in both winter-annual and rapid-cycling Arabidopsis.Plant Physiol 163:243-52 (2013).
PubMed: 23899645
Millán-Zambrano G et al.The prefoldin complex regulates chromatin dynamics during transcription elongation.PLoS Genet 9:e1003776 (2013).
ChIP
;
Saccharomyces cerevisiae
.
PubMed: 24068951
Ravnskjaer K et al.Glucagon regulates gluconeogenesis through KAT2B- and WDR5-mediated epigenetic effects.J Clin Invest 123:4318-28 (2013).
WB, IP
.
PubMed: 24051374
Yuan G et al.Histone H2A Ubiquitination Inhibits the Enzymatic Activity of H3 Lysine 36 Methyltransferases.J Biol Chem 288:30832-42 (2013).
IP
;
Mouse
.
PubMed: 24019522
Wier AD et al.Structural basis for Spt5-mediated recruitment of the Paf1 complex to chromatin.Proc Natl Acad Sci U S A 110:17290-5 (2013).
WB
;
Saccharomyces cerevisiae
.
PubMed: 24101474
Henriquez B et al.Ezh1 and Ezh2 differentially regulate PSD-95 gene transcription in developing hippocampal neurons.Mol Cell Neurosci 57:130-43 (2013).
ChIP
;
Rat
.
PubMed: 23932971
Parker SC et al.Chromatin stretch enhancer states drive cell-specific gene regulation and harbor human disease risk variants.Proc Natl Acad Sci U S A 110:17921-6 (2013).
IP
;
Human
.
PubMed: 24127591
Solovei I et al.LBR and lamin A/C sequentially tether peripheral heterochromatin and inversely regulate differentiation.Cell 152:584-98 (2013).
PubMed: 23374351
Cui X et al.Control of transposon activity by a histone H3K4 demethylase in rice.Proc Natl Acad Sci U S A 110:1953-8 (2013).
PubMed: 23319643
Kuwahara Y et al.SNF5 reexpression in malignant rhabdoid tumors regulates transcription of target genes by recruitment of SWI/SNF complexes and RNAPII to the transcription start site of their promoters.Mol Cancer Res 11:251-60 (2013).
PubMed: 23364536
Wang L et al.Genome-wide maps of polyadenylation reveal dynamic mRNA 3'-end formation in mammalian cell lineages.RNA 19:413-25 (2013).
PubMed: 23325109
Bevington S & Boyes J Transcription-coupled eviction of histones H2A/H2B governs V(D)J recombination.EMBO J 32:1381-92 (2013).
PubMed: 23463099
Ko YA et al.Cytosine methylation changes in enhancer regions of core pro-fibrotic genes characterize kidney fibrosis development.Genome Biol 14:R108 (2013).
ChIP
;
Human
.
PubMed: 24098934
Jäger N et al.Hypermutation of the inactive x chromosome is a frequent event in cancer.Cell 155:567-81 (2013).
ChIP
;
Human
.
PubMed: 24139898
Zhou Q et al.The epigenome of evolving Drosophila neo-sex chromosomes: dosage compensation and heterochromatin formation.PLoS Biol 11:e1001711 (2013).
CHIPseq
.
PubMed: 24265597
Cotton AM et al.Analysis of expressed SNPs identifies variable extents of expression from the human inactive X chromosome.Genome Biol 14:R122 (2013).
ChIP
.
PubMed: 24176135
Lim HJ et al.The G2/M regulator histone demethylase PHF8 is targeted for degradation by the anaphase-promoting complex containing CDC20.Mol Cell Biol 33:4166-80 (2013).
PubMed: 23979597
DeGennaro CM et al.Spt6 regulates intragenic and antisense transcription, nucleosome positioning, and histone modifications genome-wide in fission yeast.Mol Cell Biol 33:4779-92 (2013).
WB
.
PubMed: 24100010
Wagner KW et al.KDM2A promotes lung tumorigenesis by epigenetically enhancing ERK1/2 signaling.J Clin Invest 123:5231-46 (2013).
PubMed: 24200691
Mbogning J et al.The PAF complex and Prf1/Rtf1 delineate distinct Cdk9-dependent pathways regulating transcription elongation in fission yeast.PLoS Genet 9:e1004029 (2013).
WB
.
PubMed: 24385927
Wang AH et al.The histone chaperone Spt6 coordinates histone H3K27 demethylation and myogenesis.EMBO J 32:1075-86 (2013).
WB, ChIP
;
Mouse
.
PubMed: 23503590
Balasubramanian MN et al.Dynamic changes in genomic histone association and modification during activation of the ASNS and ATF3 genes by amino acid limitation.Biochem J 449:219-29 (2013).
PubMed: 22978410
Huang XA et al.A major epigenetic programming mechanism guided by piRNAs.Dev Cell 24:502-16 (2013).
PubMed: 23434410
Yu P et al.Spatiotemporal clustering of the epigenome reveals rules of dynamic gene regulation.Genome Res 23:352-64 (2013).
PubMed: 23033340
Kumar V et al.Uniform, optimal signal processing of mapped deep-sequencing data.Nat Biotechnol 31:615-22 (2013).
PubMed: 23770639
Nag A et al.Chromatin signature of widespread monoallelic expression.Elife 2:e01256 (2013).
ChIP
.
PubMed: 24381246
Burton A et al.Inositol pyrophosphates regulate JMJD2C-dependent histone demethylation.Proc Natl Acad Sci U S A 110:18970-5 (2013).
PubMed: 24191012
Hon GC et al.Global DNA hypomethylation coupled to repressive chromatin domain formation and gene silencing in breast cancer.Genome Res 22:246-58 (2012).
CHIPseq
.
PubMed: 22156296
Faure AJ et al.Cohesin regulates tissue-specific expression by stabilizing highly occupied cis-regulatory modules.Genome Res 22:2163-75 (2012).
PubMed: 22780989
Onoguchi M et al.A noncoding RNA regulates the neurogenin1 gene locus during mouse neocortical development.Proc Natl Acad Sci U S A 109:16939-44 (2012).
ChIP
.
PubMed: 23027973
Lin CH et al.HP1a targets the Drosophila KDM4A demethylase to a subset of heterochromatic genes to regulate H3K36me3 levels.PLoS One 7:e39758 (2012).
ChIP
.
PubMed: 22761891
Pan D et al.The histone demethylase jhdm1a regulates hepatic gluconeogenesis.PLoS Genet 8:e1002761 (2012).
ChIP
.
PubMed: 22719268
Stender JD et al.Control of proinflammatory gene programs by regulated trimethylation and demethylation of histone H4K20.Mol Cell 48:28-38 (2012).
WB
;
Mouse
.
PubMed: 22921934
Zhang W et al.High-resolution mapping of open chromatin in the rice genome.Genome Res 22:151-62 (2012).
ChIP
;
Rice
.
PubMed: 22110044
Lu C et al.IDH mutation impairs histone demethylation and results in a block to cell differentiation.Nature 483:474-8 (2012).
PubMed: 22343901
Mulji A et al.Configuration of a high-content imaging platform for hit identification and pharmacological assessment of JMJD3 demethylase enzyme inhibitors.J Biomol Screen 17:108-20 (2012).
PubMed: 22223398
Raynal NJ et al.DNA methylation does not stably lock gene expression but instead serves as a molecular mark for gene silencing memory.Cancer Res 72:1170-81 (2012).
ChIP
.
PubMed: 22219169
Kirigin FF et al.Dynamic microRNA gene transcription and processing during T cell development.J Immunol 188:3257-67 (2012).
CHIPseq
;
Mouse
.
PubMed: 22379031
Fang TC et al.Histone H3 lysine 9 di-methylation as an epigenetic signature of the interferon response.J Exp Med 209:661-9 (2012).
PubMed: 22412156
Hsu DW et al.Dynamic acetylation of lysine-4-trimethylated histone H3 and H3 variant biology in a simple multicellular eukaryote.Nucleic Acids Res : (2012).
PubMed: 22600736
Pradeepa MM et al.Psip1/Ledgf p52 binds methylated histone H3K36 and splicing factors and contributes to the regulation of alternative splicing.PLoS Genet 8:e1002717 (2012).
WB
.
PubMed: 22615581
Birnbaum RY et al.Coding exons function as tissue-specific enhancers of nearby genes.Genome Res 22:1059-68 (2012).
ChIP
.
PubMed: 22442009
Pinheiro A et al.Demethylation of the coding region triggers the activation of the human testis-specific PDHA2 gene in somatic tissues.PLoS One 7:e38076 (2012).
ChIP
.
PubMed: 22675509
Bourbousse C et al.Histone H2B monoubiquitination facilitates the rapid modulation of gene expression during Arabidopsis photomorphogenesis.PLoS Genet 8:e1002825 (2012).
ChIP
.
PubMed: 22829781
Pinter SF et al.Spreading of X chromosome inactivation via a hierarchy of defined Polycomb stations.Genome Res 22:1864-76 (2012).
ChIP
.
PubMed: 22948768
Lin YC et al.Global changes in the nuclear positioning of genes and intra- and interdomain genomic interactions that orchestrate B cell fate.Nat Immunol 13:1196-204 (2012).
CHIPseq
;
Mouse
.
PubMed: 23064439
Qi W et al.Selective inhibition of Ezh2 by a small molecule inhibitor blocks tumor cells proliferation.Proc Natl Acad Sci U S A 109:21360-5 (2012).
PubMed: 23236167
Tyan SW et al.Breast cancer cells induce stromal fibroblasts to secrete ADAMTS1 for cancer invasion through an epigenetic change.PLoS One 7:e35128 (2012).
ChIP
.
PubMed: 22514714
Paige SL et al.A temporal chromatin signature in human embryonic stem cells identifies regulators of cardiac development.Cell 151:221-32 (2012).
ChIP
.
PubMed: 22981225
Bellemer C et al.Microprocessor dynamics and interactions at endogenous imprinted C19MC microRNA genes.J Cell Sci 125:2709-20 (2012).
PubMed: 22393237
Canella D et al.A multiplicity of factors contributes to selective RNA polymerase III occupancy of a subset of RNA polymerase III genes in mouse liver.Genome Res 22:666-80 (2012).
PubMed: 22287103
Liang G et al.Kdm2b promotes induced pluripotent stem cell generation by facilitating gene activation early in reprogramming.Nat Cell Biol 14:457-66 (2012).
PubMed: 22522173
Santostefano KE et al.Fibroblast growth factor receptor 2 homodimerization rapidly reduces transcription of the pluripotency gene Nanog without dissociation of activating transcription factors.J Biol Chem 287:30507-17 (2012).
ChIP
.
PubMed: 22787153
Raab JR et al.Human tRNA genes function as chromatin insulators.EMBO J 31:330-50 (2012).
PubMed: 22085927
Goula AV et al.Transcription elongation and tissue-specific somatic CAG instability.PLoS Genet 8:e1003051 (2012).
ChIP
.
PubMed: 23209427
Sasaki M et al.D-2-hydroxyglutarate produced by mutant IDH1 perturbs collagen maturation and basement membrane function.Genes Dev 26:2038-49 (2012).
WB
.
PubMed: 22925884
Youn MY et al.JMJD5, a Jumonji C (JmjC) Domain-containing Protein, Negatively Regulates Osteoclastogenesis by Facilitating NFATc1 Protein Degradation.J Biol Chem 287:12994-3004 (2012).
PubMed: 22375008
Abdel-Wahab O et al.ASXL1 mutations promote myeloid transformation through loss of PRC2-mediated gene repression.Cancer Cell 22:180-93 (2012).
ChIP
.
PubMed: 22897849
Darvekar S et al.Identification of two independent nucleosome-binding domains in the transcriptional co-activator SPBP.Biochem J 442:65-75 (2012).
PubMed: 22081970
Gaertner B et al.Poised RNA polymerase II changes over developmental time and prepares genes for future expression.Cell Rep 2:1670-83 (2012).
PubMed: 23260668
Zhao JC et al.Cooperation between Polycomb and androgen receptor during oncogenic transformation.Genome Res 22:322-31 (2012).
ChIP
.
PubMed: 22179855
Le Martelot G et al.Genome-wide RNA polymerase II profiles and RNA accumulation reveal kinetics of transcription and associated epigenetic changes during diurnal cycles.PLoS Biol 10:e1001442 (2012).
ChIP
.
PubMed: 23209382
Sun C et al.The histone methyltransferase SDG724 mediates H3K36me2/3 deposition at MADS50 and RFT1 and promotes flowering in rice.Plant Cell 24:3235-47 (2012).
PubMed: 22892321
Zhang X et al.Integrative functional genomics identifies an enhancer looping to the SOX9 gene disrupted by the 17q24.3 prostate cancer risk locus.Genome Res 22:1437-46 (2012).
PubMed: 22665440
Zhang Y et al.Reduction of hox gene expression by histone h1 depletion.PLoS One 7:e38829 (2012).
ChIP
.
PubMed: 22701719
Tippmann SC et al.Chromatin measurements reveal contributions of synthesis and decay to steady-state mRNA levels.Mol Syst Biol 8:593 (2012).
ChIP
.
PubMed: 22806141
Tomasiewicz HC et al.Proenkephalin mediates the enduring effects of adolescent cannabis exposure associated with adult opiate vulnerability.Biol Psychiatry 72:803-10 (2012).
PubMed: 22683090
Sasaki M et al.IDH1(R132H) mutation increases murine haematopoietic progenitors and alters epigenetics.Nature 488:656-9 (2012).
WB
.
PubMed: 22763442
Chen Y et al.Systematic evaluation of factors influencing ChIP-seq fidelity.Nat Methods 9:609-14 (2012).
ChIP
.
PubMed: 22522655
Jin B et al.Linking DNA methyltransferases to epigenetic marks and nucleosome structure genome-wide in human tumor cells.Cell Rep 2:1411-24 (2012).
PubMed: 23177624
Boškovic A et al.Analysis of active chromatin modifications in early mammalian embryos reveals uncoupling of H2A.Z acetylation and H3K36 trimethylation from embryonic genome activation.Epigenetics 7:747-57 (2012).
PubMed: 22647320
McDonald OG et al.Genome-scale epigenetic reprogramming during epithelial-to-mesenchymal transition.Nat Struct Mol Biol 18:867-74 (2011).
PubMed: 21725293
Hoppmann V et al.The CW domain, a new histone recognition module in chromatin proteins.EMBO J 30:1939-52 (2011).
PubMed: 21522130
Wang D et al.Reprogramming transcription by distinct classes of enhancers functionally defined by eRNA.Nature 474:390-4 (2011).
PubMed: 21572438
Pekowska A et al.H3K4 tri-methylation provides an epigenetic signature of active enhancers.EMBO J 30:4198-210 (2011).
PubMed: 21847099
Gordon JA et al.Epigenetic regulation of early osteogenesis and mineralized tissue formation by a HOXA10-PBX1-associated complex.Cells Tissues Organs 194:146-50 (2011).
PubMed: 21597276
Batta K et al.Genome-wide function of H2B ubiquitylation in promoter and genic regions.Genes Dev 25:2254-65 (2011).
ChIP
.
PubMed: 22056671
Wang T et al.The histone demethylases Jhdm1a/1b enhance somatic cell reprogramming in a vitamin-C-dependent manner.Cell Stem Cell 9:575-87 (2011).
PubMed: 22100412
Gardner KE et al.Identification of lysine 37 of histone H2B as a novel site of methylation.PLoS One 6:e16244 (2011).
WB
.
PubMed: 21249157
Dayal S et al.High resolution analysis of the chromatin landscape of the IgE switch region in human B cells.PLoS One 6:e24571 (2011).
ChIP
;
Human
.
PubMed: 21949728
Nakayamada S et al.Early Th1 cell differentiation is marked by a Tfh cell-like transition.Immunity 35:919-31 (2011).
PubMed: 22195747
Wong P et al.Gene induction and repression during terminal erythropoiesis are mediated by distinct epigenetic changes.Blood 118:e128-38 (2011).
ChIP
.
PubMed: 21860024
Toyokawa G et al.Histone lysine methyltransferase Wolf-Hirschhorn syndrome candidate 1 is involved in human carcinogenesis through regulation of the Wnt pathway.Neoplasia 13:887-98 (2011).
PubMed: 22028615
Tan MK et al.SCF(FBXO22) regulates histone H3 lysine 9 and 36 methylation levels by targeting histone demethylase KDM4A for ubiquitin-mediated proteasomal degradation.Mol Cell Biol 31:3687-99 (2011).
PubMed: 21768309
Wu Y et al.Euchromatic subdomains in rice centromeres are associated with genes and transcription.Plant Cell 23:4054-64 (2011).
ChIP
;
Rice
.
PubMed: 22080597
Ernst J et al.Mapping and analysis of chromatin state dynamics in nine human cell types.Nature 473:43-9 (2011).
PubMed: 21441907
Kumari D et al.Repeat expansion affects both transcription initiation and elongation in friedreich ataxia cells.J Biol Chem 286:4209-15 (2011).
ChIP
.
PubMed: 21127046
Zhang J et al.Harnessing of the nucleosome-remodeling-deacetylase complex controls lymphocyte development and prevents leukemogenesis.Nat Immunol 13:86-94 (2011).
PubMed: 22080921
Bilesimo P et al.Specific histone lysine 4 methylation patterns define TR-binding capacity and differentiate direct T3 responses.Mol Endocrinol 25:225-37 (2011).
ChIP
;
Xenopus laevis
.
PubMed: 21239616
Ai N et al.Signal-induced Brd4 release from chromatin is essential for its role transition from chromatin targeting to transcriptional regulation.Nucleic Acids Res 39:9592-604 (2011).
PubMed: 21890894
Fuchs SM et al.RNA polymerase ii CTD phosphorylation regulates stability of the SET2 methyltransferase and histone H3 DI- and trimethylation at lysine 36.J Biol Chem : (2011).
PubMed: 22157004
Regnard C et al.Global Analysis of the Relationship between JIL-1 Kinase and Transcription.PLoS Genet 7:e1001327 (2011).
ChIP
;
Drosophila melanogaster
.
PubMed: 21423663
Wu SF et al.Genes for embryo development are packaged in blocks of multivalent chromatin in zebrafish sperm.Genome Res 21:578-89 (2011).
WB
;
Zebrafish
.
PubMed: 21383318
Crisucci EM & Arndt KM The Paf1 complex represses ARG1 transcription in Saccharomyces cerevisiae by promoting histone modifications.Eukaryot Cell 10:712-23 (2011).
ChIP
.
PubMed: 21498644
Hahn MA et al.Relationship between gene body DNA methylation and intragenic H3K9me3 and H3K36me3 chromatin marks.PLoS One 6:e18844 (2011).
ChIP
.
PubMed: 21526191
Pérez-Lluch S et al.Genome-wide chromatin occupancy analysis reveals a role for ASH2 in transcriptional pausing.Nucleic Acids Res 39:4628-39 (2011).
ChIP
.
PubMed: 21310711
Zhang L et al.Stable and dynamic nucleosome states during a meiotic developmental process.Genome Res 21:875-84 (2011).
PubMed: 21515815
Cheung MS et al.Systematic bias in high-throughput sequencing data and its correction by BEADS.Nucleic Acids Res 39:e103 (2011).
PubMed: 21646344
De Gobbi M et al.Generation of bivalent chromatin domains during cell fate decisions.Epigenetics Chromatin 4:9 (2011).
ChIP
;
Human
.
PubMed: 21645363
Kwon DW & Ahn SH Role of yeast JmjC-domain containing histone demethylases in actively transcribed regions.Biochem Biophys Res Commun 410:614-9 (2011).
PubMed: 21684259
Trejbalová K et al.Epigenetic regulation of transcription and splicing of syncytins, fusogenic glycoproteins of retroviral origin.Nucleic Acids Res 39:8728-39 (2011).
ChIP
;
Human
.
PubMed: 21771862
Widiez T et al.High nitrogen insensitive 9 (HNI9)-mediated systemic repression of root NO3- uptake is associated with changes in histone methylation.Proc Natl Acad Sci U S A 108:13329-34 (2011).
ChIP
.
PubMed: 21788519
Hainer SJ & Martens JA Identification of histone mutants that are defective for transcription-coupled nucleosome occupancy.Mol Cell Biol 31:3557-68 (2011).
WB
;
Saccharomyces cerevisiae
.
PubMed: 21730290
Zhang CC et al.RPL1, a Gene Involved in Epigenetic Processes Regulates Phenotypic Plasticity in Rice.Mol Plant : (2011).
PubMed: 22131052
Movassagh M et al.Distinct epigenomic features in end-stage failing human hearts.Circulation 124:2411-22 (2011).
ChIP
;
Human
.
PubMed: 22025602
Rahman S et al.The Brd4 extraterminal domain confers transcription activation independent of pTEFb by recruiting multiple proteins, including NSD3.Mol Cell Biol 31:2641-52 (2011).
ChIP
.
PubMed: 21555454
Hung T et al.Extensive and coordinated transcription of noncoding RNAs within cell-cycle promoters.Nat Genet 43:621-9 (2011).
ChIP
;
Human
.
PubMed: 21642992
Xie L et al.KDM5B regulates embryonic stem cell self-renewal and represses cryptic intragenic transcription.EMBO J 30:1473-84 (2011).
WB
;
Mouse
.
PubMed: 21448134
Wilhelm BT et al.Differential patterns of intronic and exonic DNA regions with respect to RNA polymerase II occupancy, nucleosome density and H3K36me3 marking in fission yeast.Genome Biol 12:R82 (2011).
ChIP/Chip
;
Schizosaccharomyces pombe
.
PubMed: 21859475
Shieh GS et al.H2B ubiquitylation is part of chromatin architecture that marks exon-intron structure in budding yeast.BMC Genomics 12:627 (2011).
ChIP
;
Saccharomyces cerevisiae
.
PubMed: 22188810
Milcarek C et al.The Eleven-Nineteen Lysine-rich Leukemia Gene (ELL2) Influences the Histone H3 Protein Modifications Accompanying the Shift to Secretory Immunoglobulin Heavy Chain mRNA Production.J Biol Chem 286:33795-803 (2011).
ChIP
;
Mouse
.
PubMed: 21832080
Yildirim E et al.X-chromosome hyperactivation in mammals via nonlinear relationships between chromatin states and transcription.Nat Struct Mol Biol 19:56-61 (2011).
ChIP
.
PubMed: 22139016
Chantalat S et al.Histone H3 trimethylation at lysine 36 is associated with constitutive and facultative heterochromatin.Genome Res 21:1426-37 (2011).
PubMed: 21803857
Jang IC et al.Rapid and reversible light-mediated chromatin modifications of Arabidopsis phytochrome A locus.Plant Cell 23:459-70 (2011).
ChIP
.
PubMed: 21317377
Harris RA et al.Comparison of sequencing-based methods to profile DNA methylation and identification of monoallelic epigenetic modifications.Nat Biotechnol 28:1097-105 (2010).
PubMed: 20852635
Ko JH et al.Growth habit determination by the balance of histone methylation activities in Arabidopsis.EMBO J 29:3208-15 (2010).
PubMed: 20711170
Gómez-del Arco P et al.Alternative promoter usage at the Notch1 locus supports ligand-independent signaling in T cell development and leukemogenesis.Immunity 33:685-98 (2010).
PubMed: 21093322
Tanaka Y et al.JmjC enzyme KDM2A is a regulator of rRNA transcription in response to starvation.EMBO J 29:1510-22 (2010).
PubMed: 20379134
Loenarz C et al.PHF8, a gene associated with cleft lip/palate and mental retardation, encodes for an Nepsilon-dimethyl lysine demethylase.Hum Mol Genet 19:217-22 (2010).
WB
;
Cow
.
PubMed: 19843542
Lin LJ et al.Asf1 can promote trimethylation of H3 K36 by Set2.Mol Cell Biol 30:1116-29 (2010).
WB
;
Saccharomyces cerevisiae
.
PubMed: 20048053
Paakinaho V et al.Glucocorticoid receptor activates poised FKBP51 locus through long-distance interactions.Mol Endocrinol 24:511-25 (2010).
PubMed: 20093418
Du HN & Briggs SD A nucleosome surface formed by histone H4, H2A, and H3 residues is needed for proper histone H3 Lys36 methylation, histone acetylation, and repression of cryptic transcription.J Biol Chem 285:11704-13 (2010).
ChIP
;
Saccharomyces cerevisiae
.
PubMed: 20139424
Gan Q et al.Monovalent and unpoised status of most genes in undifferentiated cell-enriched Drosophila testis.Genome Biol 11:R42 (2010).
ChIP
;
Drosophila melanogaster
.
PubMed: 20398323
Lucio-Eterovic AK et al.Role for the nuclear receptor-binding SET domain protein 1 (NSD1) methyltransferase in coordinating lysine 36 methylation at histone 3 with RNA polymerase II function.Proc Natl Acad Sci U S A 107:16952-7 (2010).
Human
.
PubMed: 20837538
Huff JT et al.Reciprocal intronic and exonic histone modification regions in humans.Nat Struct Mol Biol 17:1495-9 (2010).
ChIP
;
Human
.
PubMed: 21057525
Sinha KM et al.Regulation of the osteoblast-specific transcription factor Osterix by NO66, a Jumonji family histone demethylase.EMBO J 29:68-79 (2010).
WB
.
PubMed: 19927124
Song YH & Ahn SH A Bre1-associated protein, large 1 (Lge1), promotes H2B ubiquitylation during the early stages of transcription elongation.J Biol Chem 285:2361-7 (2010).
WB
;
Saccharomyces cerevisiae
.
PubMed: 19923226
Tao Y et al.Lsh Mediated RNA Polymerase II Stalling at HoxC6 and HoxC8 Involves DNA Methylation.PLoS One 5:e9163 (2010).
WB
;
Mouse
.
PubMed: 20161795
Sun J & Li R Human negative elongation factor activates transcription and regulates alternative transcription initiation.J Biol Chem 285:6443-52 (2010).
ChIP
;
Human
.
PubMed: 20028984
Zheng Y et al.Role of conserved non-coding DNA elements in the Foxp3 gene in regulatory T-cell fate.Nature 463:808-12 (2010).
ChIP
;
Mouse
.
PubMed: 20072126
Malik S et al.Rad26p, a transcription-coupled repair factor, is recruited to the site of DNA lesion in an elongating RNA polymerase II-dependent manner in vivo.Nucleic Acids Res 38:1461-77 (2010).
ChIP
.
PubMed: 20007604
Wen H et al.Recognition of Histone H3K4 Trimethylation by the Plant Homeodomain of PHF2 Modulates Histone Demethylation.J Biol Chem 285:9322-6 (2010).
ICC/IF
;
Human
.
PubMed: 20129925
Huang C et al.Dual-specificity histone demethylase KIAA1718 (KDM7A) regulates neural differentiation through FGF4.Cell Res 20:154-65 (2010).
WB
;
Human
.
PubMed: 20084082
Goldberg AD et al.Distinct factors control histone variant H3.3 localization at specific genomic regions.Cell 140:678-91 (2010).
PubMed: 20211137
Vastenhouw NL et al.Chromatin signature of embryonic pluripotency is established during genome activation.Nature 464:922-6 (2010).
WB, ChIP
;
Zebrafish
.
PubMed: 20336069
Paul TA et al.Signatures of polycomb repression and reduced H3K4 trimethylation are associated with p15INK4b DNA methylation in AML.Blood 115:3098-108 (2010).
ChIP
;
Human
.
PubMed: 20190193
Herz HM et al.The H3K27me3 demethylase dUTX is a suppressor of notch- and Rb-dependent tumors in Drosophila.Mol Cell Biol 30:2485-97 (2010).
IHC
;
Drosophila melanogaster
.
PubMed: 20212086
Punga T & Bühler M Long intronic GAA repeats causing Friedreich ataxia impede transcription elongation.EMBO Mol Med 2:120-9 (2010).
ChIP
;
Human
.
PubMed: 20373285
Yu J et al.An integrated network of androgen receptor, polycomb, and TMPRSS2-ERG gene fusions in prostate cancer progression.Cancer Cell 17:443-54 (2010).
ChIP
;
Human
.
PubMed: 20478527
Aiden AP et al.Wilms tumor chromatin profiles highlight stem cell properties and a renal developmental network.Cell Stem Cell 6:591-602 (2010).
ChIP
;
Human
.
PubMed: 20569696
Hsia DA et al.KDM8, a H3K36me2 histone demethylase that acts in the cyclin A1 coding region to regulate cancer cell proliferation.Proc Natl Acad Sci U S A 107:9671-6 (2010).
WB
;
Human
.
PubMed: 20457893
Duns G et al.Histone methyltransferase gene SETD2 is a novel tumor suppressor gene in clear cell renal cell carcinoma.Cancer Res 70:4287-91 (2010).
WB
;
Human
.
PubMed: 20501857
Liu W et al.PHF8 mediates histone H4 lysine 20 demethylation events involved in cell cycle progression.Nature 466:508-12 (2010).
WB
;
Human
.
PubMed: 20622854
Dhayalan A et al.The Dnmt3a PWWP domain reads histone 3 lysine 36 trimethylation and guides DNA methylation.J Biol Chem 285:26114-20 (2010).
WB
.
PubMed: 20547484
Pattenden SG et al.Features of cryptic promoters and their varied reliance on bromodomain-containing factors.PLoS One 5:e12927 (2010).
PubMed: 20886085
Palma K et al.Autoimmunity in Arabidopsis acd11 is mediated by epigenetic regulation of an immune receptor.PLoS Pathog 6: (2010).
ChIP
;
Arabidopsis thaliana
.
PubMed: 20949080
Lin H et al.Coordinated regulation of active and repressive histone methylations by a dual-specificity histone demethylase ceKDM7A from Caenorhabditis elegans.Cell Res 20:899-907 (2010).
PubMed: 20567262
Wood JG et al.Chromatin remodeling in the aging genome of Drosophila.Aging Cell 9:971-8 (2010).
PubMed: 20961390
Zhu Z et al.PHF8 is a histone H3K9me2 demethylase regulating rRNA synthesis.Cell Res 20:794-801 (2010).
ChIP
.
PubMed: 20531378
Fang R et al.Human LSD2/KDM1b/AOF1 Regulates Gene Transcription by Modulating Intragenic H3K4me2 Methylation.Mol Cell 39:222-233 (2010).
ChIP
.
PubMed: 20670891
Wei L et al.Discrete roles of STAT4 and STAT6 transcription factors in tuning epigenetic modifications and transcription during T helper cell differentiation.Immunity 32:840-51 (2010).
PubMed: 20620946
Muramoto T et al.Methylation of H3K4 Is required for inheritance of active transcriptional states.Curr Biol 20:397-406 (2010).
PubMed: 20188556
Buro LJ et al.Menin and RNF20 recruitment is associated with dynamic histone modifications that regulate signal transducer and activator of transcription 1 (STAT1)-activated transcription of the interferon regulatory factor 1 gene (IRF1).Epigenetics Chromatin 3:16 (2010).
PubMed: 20825659
Drouin S et al.DSIF and RNA polymerase II CTD phosphorylation coordinate the recruitment of Rpd3S to actively transcribed genes.PLoS Genet 6:e1001173 (2010).
ChIP
.
PubMed: 21060864
Gordon JA et al.Pbx1 represses osteoblastogenesis by blocking Hoxa10-mediated recruitment of chromatin remodeling factors.Mol Cell Biol 30:3531-41 (2010).
PubMed: 20439491
Inagaki S et al.Autocatalytic differentiation of epigenetic modifications within the Arabidopsis genome.EMBO J 29:3496-506 (2010).
PubMed: 20834229
Berr A et al.Arabidopsis histone methyltransferase SET DOMAIN GROUP8 mediates induction of the jasmonate/ethylene pathway genes in plant defense response to necrotrophic fungi.Plant Physiol 154:1403-14 (2010).
PubMed: 20810545
Berr A et al.Arabidopsis SET DOMAIN GROUP2 is required for H3K4 trimethylation and is crucial for both sporophyte and gametophyte development.Plant Cell 22:3232-48 (2010).
PubMed: 21037105
Jia L et al.Functional enhancers at the gene-poor 8q24 cancer-linked locus.PLoS Genet 5:e1000597 (2009).
ChIP
.
PubMed: 19680443
Kolasinska-Zwierz P et al.Differential chromatin marking of introns and expressed exons by H3K36me3.Nat Genet : (2009).
ChIP
.
PubMed: 19182803
Tamura T et al.Inducible deposition of the histone variant H3.3 in interferon-stimulated genes.J Biol Chem 284:12217-25 (2009).
PubMed: 19244243
Schnetz MP et al.Genomic distribution of CHD7 on chromatin tracks H3K4 methylation patterns.Genome Res 19:590-601 (2009).
WB
.
PubMed: 19251738
Wilson LM et al.Insulin but not glucagon gene is silenced in human pancreas-derived mesenchymal stem cells.Stem Cells 27:2703-11 (2009).
PubMed: 19785038
Mestdagh P et al.A novel and universal method for microRNA RT-qPCR data normalization.Genome Biol 10:R64 (2009).
PubMed: 19531210
Wang X et al.Genome-wide and organ-specific landscapes of epigenetic modifications and their relationships to mRNA and small RNA transcriptomes in maize.Plant Cell 21:1053-69 (2009).
ChIP
.
PubMed: 19376930
Grini PE et al.The ASH1 HOMOLOG 2 (ASHH2) histone H3 methyltransferase is required for ovule and anther development in Arabidopsis.PLoS One 4:e7817 (2009).
ChIP
.
PubMed: 19915673
Wirth M et al.HIS-24 linker histone and SIR-2.1 deacetylase induce H3K27me3 in the Caenorhabditis elegans germ line.Mol Cell Biol 29:3700-9 (2009).
IHC-Fr
;
Caenorhabditis elegans
.
PubMed: 19380489
Egloff S et al.Chromatin structure is implicated in "late" elongation checkpoints on the U2 snRNA and beta-actin genes.Mol Cell Biol 29:4002-13 (2009).
ChIP
;
Human
.
PubMed: 19451231
Hodges E et al.High definition profiling of mammalian DNA methylation by array capture and single molecule bisulfite sequencing.Genome Res 19:1593-605 (2009).
CHIPseq
;
Human
.
PubMed: 19581485
Glover-Cutter K et al.TFIIH-associated Cdk7 kinase functions in phosphorylation of C-terminal domain Ser7 residues, promoter-proximal pausing, and termination by RNA polymerase II.Mol Cell Biol 29:5455-64 (2009).
PubMed: 19667075
Jacinto FV et al.Impaired recruitment of the histone methyltransferase DOT1L contributes to the incomplete reactivation of tumor suppressor genes upon DNA demethylation.Oncogene 28:4212-24 (2009).
ChIP
;
Human
.
PubMed: 19734945
Kim T & Buratowski S Dimethylation of H3K4 by Set1 recruits the Set3 histone deacetylase complex to 5' transcribed regions.Cell 137:259-72 (2009).
ChIP
;
Saccharomyces cerevisiae
.
PubMed: 19379692
Gargiulo G et al.NA-Seq: a discovery tool for the analysis of chromatin structure and dynamics during differentiation.Dev Cell 16:466-81 (2009).
ChIP
.
PubMed: 19289091
Schmitz RJ et al.Histone H2B deubiquitination is required for transcriptional activation of FLOWERING LOCUS C and for proper control of flowering in Arabidopsis.Plant Physiol 149:1196-204 (2009).
WB
;
Arabidopsis thaliana
.
PubMed: 19091875
Qiu H et al.Phosphorylation of the Pol II CTD by KIN28 enhances BUR1/BUR2 recruitment and Ser2 CTD phosphorylation near promoters.Mol Cell 33:752-62 (2009).
ChIP
.
PubMed: 19328068
Ciccone DN et al.KDM1B is a histone H3K4 demethylase required to establish maternal genomic imprints.Nature 461:415-8 (2009).
ICC/IF
;
Mouse
.
PubMed: 19727073
Koshibu K et al.Protein phosphatase 1 regulates the histone code for long-term memory.J Neurosci 29:13079-89 (2009).
WB
;
Mouse
.
PubMed: 19828821
Esnault G et al.Transcription factor CTF1 acts as a chromatin domain boundary that shields human telomeric genes from silencing.Mol Cell Biol 29:2409-18 (2009).
ChIP
;
Human
.
PubMed: 19273604
Chen Y et al.DSIF, the Paf1 complex, and Tat-SF1 have nonredundant, cooperative roles in RNA polymerase II elongation.Genes Dev 23:2765-77 (2009).
WB
;
Human
.
PubMed: 19952111
Makkonen H et al.Long-range activation of FKBP51 transcription by the androgen receptor via distal intronic enhancers.Nucleic Acids Res 37:4135-48 (2009).
ChIP
.
PubMed: 19433513
Luo L et al.The nuclear periphery of embryonic stem cells is a transcriptionally permissive and repressive compartment.J Cell Sci 122:3729-37 (2009).
Xenopus laevis
.
PubMed: 19773359
Psathas JN et al.Set2-dependent K36 methylation is regulated by novel intratail interactions within H3.Mol Cell Biol 29:6413-26 (2009).
WB, ChIP
;
Saccharomyces cerevisiae
.
PubMed: 19822661
Gorchakov AA et al.Long-range spreading of dosage compensation in Drosophila captures transcribed autosomal genes inserted on X.Genes Dev 23:2266-71 (2009).
ChIP
;
Drosophila melanogaster
.
PubMed: 19797766
Li Y et al.The target of the NSD family of histone lysine methyltransferases depends on the nature of the substrate.J Biol Chem 284:34283-95 (2009).
PubMed: 19808676
Racanelli AC et al.A mouse gene that coordinates epigenetic controls and transcriptional interference to achieve tissue-specific expression.Mol Cell Biol 28:836-48 (2008).
ChIP
;
Mouse
.
PubMed: 17998333
Nelson JD et al.Transcription of laminin gamma1 chain gene in rat mesangial cells: constitutive and inducible RNA polymerase II recruitment and chromatin states.Am J Physiol Renal Physiol 294:F525-33 (2008).
ChIP
;
Rat
.
PubMed: 18184742
Sun XJ et al.Genome-wide survey and developmental expression mapping of zebrafish SET domain-containing genes.PLoS One 3:e1499 (2008).
IHC
;
Zebrafish
.
PubMed: 18231586
Merker JD et al.The histone methylase Set2p and the histone deacetylase Rpd3p repress meiotic recombination at the HIS4 meiotic recombination hotspot in Saccharomyces cerevisiae.DNA Repair (Amst) 7:1298-308 (2008).
ChIP
;
Saccharomyces cerevisiae
.
PubMed: 18515193
Postberg J et al.Spatial and temporal plasticity of chromatin during programmed DNA-reorganization in Stylonychia macronuclear development.Epigenetics Chromatin 1:3 (2008).
PubMed: 19014664
Edmunds JW et al.Dynamic histone H3 methylation during gene induction: HYPB/Setd2 mediates all H3K36 trimethylation.EMBO J 27:406-20 (2008).
ChIP
;
Mouse
.
PubMed: 18157086
Williams A et al.Position effect variegation and imprinting of transgenes in lymphocytes.Nucleic Acids Res 36:2320-9 (2008).
ChIP
;
Mouse
.
PubMed: 18296483
Lloret-Llinares M et al.Characterization of Drosophila melanogaster JmjC+N histone demethylases.Nucleic Acids Res : (2008).
ICC/IF
;
Drosophila melanogaster
.
PubMed: 18375980
Smith ER et al.Drosophila UTX is a histone H3 Lys27 demethylase that colocalizes with the elongating form of RNA polymerase II.Mol Cell Biol 28:1041-6 (2008).
WB
;
Drosophila melanogaster
.
PubMed: 18039863
Xu L et al.Di- and tri- but not monomethylation on histone H3 lysine 36 marks active transcription of genes involved in flowering time regulation and other processes in Arabidopsis thaliana.Mol Cell Biol 28:1348-60 (2008).
WB
;
Arabidopsis thaliana
.
PubMed: 18070919
Chou SD & Tomasi TB Spatial distribution of histone methylation during MHC class II expression.Mol Immunol 45:971-80 (2008).
PubMed: 17850872
Steger DJ et al.DOT1L/KMT4 recruitment and H3K79 methylation are ubiquitously coupled with gene transcription in mammalian cells.Mol Cell Biol 28:2825-39 (2008).
ChIP
;
Mouse
.
PubMed: 18285465
Bell O et al.Transcription-coupled methylation of histone H3 at lysine 36 regulates dosage compensation by enhancing recruitment of the MSL complex in Drosophila melanogaster.Mol Cell Biol 28:3401-9 (2008).
WB
;
Drosophila melanogaster
.
PubMed: 18347056
Lagarou A et al.dKDM2 couples histone H2A ubiquitylation to histone H3 demethylation during Polycomb group silencing.Genes Dev 22:2799-810 (2008).
WB
;
Drosophila melanogaster
.
PubMed: 18923078
Vitaliano-Prunier A et al.Ubiquitylation of the COMPASS component Swd2 links H2B ubiquitylation to H3K4 trimethylation.Nat Cell Biol 10:1365-71 (2008).
WB
;
Saccharomyces cerevisiae
.
PubMed: 18849979
Ku M et al.Genomewide analysis of PRC1 and PRC2 occupancy identifies two classes of bivalent domains.PLoS Genet 4:e1000242 (2008).
ChIP
.
PubMed: 18974828
Biswas D et al.Different genetic functions for the Rpd3(L) and Rpd3(S) complexes suggest competition between NuA4 and Rpd3(S).Mol Cell Biol 28:4445-58 (2008).
ChIP
.
PubMed: 18490440
Han Y et al.Orientation-dependent regulation of integrated HIV-1 expression by host gene transcriptional readthrough.Cell Host Microbe 4:134-46 (2008).
ChIP
.
PubMed: 18692773
Lian Z et al.A genomic analysis of RNA polymerase II modification and chromatin architecture related to 3' end RNA polyadenylation.Genome Res 18:1224-37 (2008).
PubMed: 18487515
Yoh SM et al.The Iws1:Spt6:CTD complex controls cotranscriptional mRNA biosynthesis and HYPB/Setd2-mediated histone H3K36 methylation.Genes Dev 22:3422-34 (2008).
PubMed: 19141475
Krivtsov AV et al.H3K79 methylation profiles define murine and human MLL-AF4 leukemias.Cancer Cell 14:355-68 (2008).
PubMed: 18977325
Rabinovich A et al.E2F in vivo binding specificity: comparison of consensus versus nonconsensus binding sites.Genome Res 18:1763-77 (2008).
PubMed: 18836037
Riu E et al.Histone modifications are associated with the persistence or silencing of vector-mediated transgene expression in vivo.Mol Ther 15:1348-55 (2007).
PubMed: 17457320
Christensen J et al.RBP2 belongs to a family of demethylases, specific for tri-and dimethylated lysine 4 on histone 3.Cell 128:1063-76 (2007).
PubMed: 17320161
De Santa F et al.The histone H3 lysine-27 demethylase Jmjd3 links inflammation to inhibition of polycomb-mediated gene silencing.Cell 130:1083-94 (2007).
WB, ICC/IF
;
Human
.
PubMed: 17825402
Ingvarsdottir K et al.Histone H3 K4 demethylation during activation and attenuation of GAL1 transcription in Saccharomyces cerevisiae.Mol Cell Biol 27:7856-64 (2007).
PubMed: 17875926
Andersen EC & Horvitz HR Two C. elegans histone methyltransferases repress lin-3 EGF transcription to inhibit vulval development.Development 134:2991-9 (2007).
WB
;
Caenorhabditis elegans
.
PubMed: 17634190
Yokoyama R et al.A plasmid model system shows that Drosophila dosage compensation depends on the global acetylation of histone H4 at lysine 16 and is not affected by depletion of common transcription elongation chromatin marks.Mol Cell Biol 27:7865-70 (2007).
PubMed: 17875941
Gregory GD et al.Mammalian ASH1L is a histone methyltransferase that occupies the transcribed region of active genes.Mol Cell Biol 27:8466-79 (2007).
PubMed: 17923682
Fang J et al.The Saccharomyces cerevisiae histone demethylase Jhd1 fine-tunes the distribution of H3K36me2.Mol Cell Biol 27:5055-65 (2007).
WB, ChIP
.
PubMed: 17470555
Lee MG et al.Physical and functional association of a trimethyl H3K4 demethylase and Ring6a/MBLR, a polycomb-like protein.Cell 128:877-87 (2007).
WB
;
Human
.
PubMed: 17320162
Wang GG et al.NUP98-NSD1 links H3K36 methylation to Hox-A gene activation and leukaemogenesis.Nat Cell Biol 9:804-12 (2007).
ChIP
;
Mouse
.
PubMed: 17589499
Larschan E et al.MSL complex is attracted to genes marked by H3K36 trimethylation using a sequence-independent mechanism.Mol Cell 28:121-33 (2007).
ChIP/Chip
;
Drosophila melanogaster
.
PubMed: 17936709
Secombe J et al.The Trithorax group protein Lid is a trimethyl histone H3K4 demethylase required for dMyc-induced cell growth.Genes Dev 21:537-51 (2007).
PubMed: 17311883
Barski A et al.High-resolution profiling of histone methylations in the human genome.Cell 129:823-37 (2007).
PubMed: 17512414
Guenther MG et al.A chromatin landmark and transcription initiation at most promoters in human cells.Cell 130:77-88 (2007).
ChIP/Chip
;
Human
.
PubMed: 17632057
Hayakawa T et al.RBP2 is an MRG15 complex component and down-regulates intragenic histone H3 lysine 4 methylation.Genes Cells 12:811-26 (2007).
WB
;
Human
.
PubMed: 17573780
Klose RJ et al.Demethylation of histone H3K36 and H3K9 by Rph1: a vestige of an H3K9 methylation system in Saccharomyces cerevisiae?Mol Cell Biol 27:3951-61 (2007).
WB
;
Saccharomyces cerevisiae
.
PubMed: 17371840
Morris SA et al.Identification of histone H3 lysine 36 acetylation as a highly conserved histone modification.J Biol Chem 282:7632-40 (2007).
WB
;
Saccharomyces cerevisiae
.
PubMed: 17189264
Chu Y et al.Regulation of histone modification and cryptic transcription by the Bur1 and Paf1 complexes.EMBO J 26:4646-56 (2007).
WB
;
Saccharomyces cerevisiae
.
PubMed: 17948059
Abarrategui I & Krangel MS Noncoding transcription controls downstream promoters to regulate T-cell receptor alpha recombination.EMBO J 26:4380-90 (2007).
WB
;
Mouse
.
PubMed: 17882258
Agger K et al.UTX and JMJD3 are histone H3K27 demethylases involved in HOX gene regulation and development.Nature 449:731-4 (2007).
WB, ICC/IF
;
Human
.
PubMed: 17713478
Hong S et al.Identification of JmjC domain-containing UTX and JMJD3 as histone H3 lysine 27 demethylases.Proc Natl Acad Sci U S A 104:18439-44 (2007).
PubMed: 18003914
Xiao T et al.The RNA polymerase II kinase Ctk1 regulates positioning of a 5' histone methylation boundary along genes.Mol Cell Biol 27:721-31 (2007).
PubMed: 17088384
Rybtsova N et al.Transcription-coupled deposition of histone modifications during MHC class II gene activation.Nucleic Acids Res 35:3431-41 (2007).
PubMed: 17478518
Kim T & Buratowski S Two Saccharomyces cerevisiae JmjC domain proteins demethylate histone H3 Lys36 in transcribed regions to promote elongation.J Biol Chem 282:20827-35 (2007).
PubMed: 17525156
Mikkelsen TS et al.Genome-wide maps of chromatin state in pluripotent and lineage-committed cells.Nature 448:553-60 (2007).
PubMed: 17603471
Kirmizis A et al.Arginine methylation at histone H3R2 controls deposition of H3K4 trimethylation.Nature 449:928-32 (2007).
WB
;
Saccharomyces cerevisiae
.
PubMed: 17898715
Guccione E et al.Methylation of histone H3R2 by PRMT6 and H3K4 by an MLL complex are mutually exclusive.Nature 449:933-7 (2007).
ChIP
;
Human
.
PubMed: 17898714
Chu Y et al.The BUR1 cyclin-dependent protein kinase is required for the normal pattern of histone methylation by SET2.Mol Cell Biol 26:3029-38 (2006).
WB
;
Saccharomyces cerevisiae
.
PubMed: 16581778
Zhang P et al.Structure of human MRG15 chromo domain and its binding to Lys36-methylated histone H3.Nucleic Acids Res 34:6621-8 (2006).
PubMed: 17135209
Vakoc CR et al.Profile of histone lysine methylation across transcribed mammalian chromatin.Mol Cell Biol 26:9185-95 (2006).
PubMed: 17030614
Whetstine JR et al.Reversal of histone lysine trimethylation by the JMJD2 family of histone demethylases.Cell 125:467-81 (2006).
PubMed: 16603238
Guccione E et al.Myc-binding-site recognition in the human genome is determined by chromatin context.Nat Cell Biol 8:764-70 (2006).
PubMed: 16767079
Nelson CJ et al.Proline isomerization of histone H3 regulates lysine methylation and gene expression.Cell 126:905-16 (2006).
PubMed: 16959570
Loyola A et al.PTMs on H3 variants before chromatin assembly potentiate their final epigenetic state.Mol Cell 24:309-16 (2006).
PubMed: 17052464
Sripathy SP et al.The KAP1 corepressor functions to coordinate the assembly of de novo HP1-demarcated microenvironments of heterochromatin required for KRAB zinc finger protein-mediated transcriptional repression.Mol Cell Biol 26:8623-38 (2006).
ChIP
.
PubMed: 16954381
Bannister AJ et al.Spatial distribution of Di- and tri-methyl lysine 36 of histone H3 at active genes.J Biol Chem 280:17732-6 (2005).
PubMed: 15760899
Pokholok DK et al.Genome-wide map of nucleosome acetylation and methylation in yeast.Cell 122:517-27 (2005).
PubMed: 16122420
Morillon A et al.Dynamic lysine methylation on histone H3 defines the regulatory phase of gene transcription.Mol Cell 18:723-34 (2005).
PubMed: 15949446
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