Bandini C et al.IRF4 Mediates the Oncogenic Effects of STAT3 in Anaplastic Large Cell Lymphomas.Cancers (Basel) 10:N/A (2018).
PubMed: 29346274
Coluccio A et al.Individual retrotransposon integrants are differentially controlled by KZFP/KAP1-dependent histone methylation, DNA methylation and TET-mediated hydroxymethylation in naïve embryonic stem cells.Epigenetics Chromatin 11:7 (2018).
CHIPseq
.
PubMed: 29482634
Castino MR et al.Persistent histone modifications at the BDNF and Cdk-5 promoters following extinction of nicotine-seeking in rats.Genes Brain Behav 17:98-106 (2018).
ChIP
;
Rat
.
PubMed: 28857504
Espana-Agusti J et al.Loss of PBRM1 rescues VHL dependent replication stress to promote renal carcinogenesis.Nat Commun 8:2026 (2017).
WB, ICC
;
Mouse
.
PubMed: 29229903
Wang Y et al.Ezh2 Acts as a Tumor Suppressor in Kras-driven Lung Adenocarcinoma.Int J Biol Sci 13:652-659 (2017).
PubMed: 28539837
Willi M et al.Facultative CTCF sites moderate mammary super-enhancer activity and regulate juxtaposed gene in non-mammary cells.Nat Commun 8:16069 (2017).
PubMed: 28714474
Gatto S et al.ICF-specific DNMT3B dysfunction interferes with intragenic regulation of mRNA transcription and alternative splicing.Nucleic Acids Res 45:5739-5756 (2017).
ChIP
.
PubMed: 28334849
Rajabi H et al.MUC1-C activates EZH2 expression and function in human cancer cells.Sci Rep 7:7481 (2017).
WB, ChIP
;
Human
.
PubMed: 28785086
Liu B et al.Long non-coding RNA HOXA11-AS promotes the proliferation HCC cells by epigenetically silencing DUSP5.Oncotarget 8:109509-109521 (2017).
PubMed: 29312625
Duraisamy AJ et al.Crosstalk Between Histone and DNA Methylation in Regulation of Retinal Matrix Metalloproteinase-9 in Diabetes.Invest Ophthalmol Vis Sci 58:6440-6448 (2017).
PubMed: 29261844
Stamato MA et al.Inhibition of EZH2 triggers the tumor suppressive miR-29b network in multiple myeloma.Oncotarget 8:106527-106537 (2017).
PubMed: 29290968
He R et al.OCT4 supports extended LIF-independent self-renewal and maintenance of transcriptional and epigenetic networks in embryonic stem cells.Sci Rep 7:16360 (2017).
PubMed: 29180818
Posukh OV et al.Functional dissection of Drosophila melanogaster SUUR protein influence on H3K27me3 profile.Epigenetics Chromatin 10:56 (2017).
PubMed: 29191233
Cattoni DI et al.Single-cell absolute contact probability detection reveals chromosomes are organized by multiple low-frequency yet specific interactions.Nat Commun 8:1753 (2017).
PubMed: 29170434
Marín-Béjar O et al.The human lncRNA LINC-PINT inhibits tumor cell invasion through a highly conserved sequence element.Genome Biol 18:202 (2017).
PubMed: 29078818
Nakade K et al.Jun dimerization protein 2 controls hypoxia-induced replicative senescence via both the p16Ink4a-pRb and Arf-p53 pathways.FEBS Open Bio 7:1793-1804 (2017).
PubMed: 29123987
Ju J et al.NatD promotes lung cancer progression by preventing histone H4 serine phosphorylation to activate Slug expression.Nat Commun 8:928 (2017).
PubMed: 29030587
Wang F et al.Rlim-Dependent and -Independent Pathways for X Chromosome Inactivation in Female ESCs.Cell Rep 21:3691-3699 (2017).
PubMed: 29281819
Zeybel M et al.A Proof-of-Concept for Epigenetic Therapy of Tissue Fibrosis: Inhibition of Liver Fibrosis Progression by 3-Deazaneplanocin A.Mol Ther 25:218-231 (2017).
PubMed: 28129116
Fenouille N et al.The creatine kinase pathway is a metabolic vulnerability in EVI1-positive acute myeloid leukemia.Nat Med 23:301-313 (2017).
PubMed: 28191887
Meers MP et al.Histone gene replacement reveals a post-transcriptional role for H3K36 in maintaining metazoan transcriptome fidelity.Elife 6:N/A (2017).
PubMed: 28346137
Zapata JC et al.The Human Immunodeficiency Virus 1 ASP RNA promotes viral latency by recruiting the Polycomb Repressor Complex 2 and promoting nucleosome assembly.Virology 506:34-44 (2017).
PubMed: 28340355
Carnesecchi J et al.ERRa induces H3K9 demethylation by LSD1 to promote cell invasion.Proc Natl Acad Sci U S A 114:3909-3914 (2017).
PubMed: 28348226
Luo D et al.Deltex2 represses MyoD expression and inhibits myogenic differentiation by acting as a negative regulator of Jmjd1c.Proc Natl Acad Sci U S A 114:E3071-E3080 (2017).
PubMed: 28351977
Teif VB et al.Nucleosome repositioning during differentiation of a human myeloid leukemia cell line.Nucleus 8:188-204 (2017).
PubMed: 28406749
Ma S et al.Epigenetic regulator CXXC5 recruits DNA demethylase Tet2 to regulate TLR7/9-elicited IFN response in pDCs.J Exp Med 214:1471-1491 (2017).
PubMed: 28416650
Kataruka S et al.Mrhl Long Noncoding RNA Mediates Meiotic Commitment of Mouse Spermatogonial Cells by Regulating Sox8 Expression.Mol Cell Biol 37:N/A (2017).
PubMed: 28461394
Soto-Feliciano YM et al.PHF6 regulates phenotypic plasticity through chromatin organization within lineage-specific genes.Genes Dev 31:973-989 (2017).
PubMed: 28607179
Leung W et al.Retrotransposons Are the Major Contributors to the Expansion of theDrosophila ananassaeMuller F Element.G3 (Bethesda) 7:2439-2460 (2017).
PubMed: 28667019
Lau-Corona D et al.Feminization of male mouse liver by persistent growth hormone stimulation: Activation of sex-biased transcriptional networks and dynamic changes in chromatin states.Mol Cell Biol N/A:N/A (2017).
PubMed: 28694329
Kim DH et al.Modular function of long noncoding RNA, COLDAIR, in the vernalization response.PLoS Genet 13:e1006939 (2017).
PubMed: 28759577
Shin HM et al.Transient expression of ZBTB32 in anti-viral CD8+ T cells limits the magnitude of the effector response and the generation of memory.PLoS Pathog 13:e1006544 (2017).
PubMed: 28827827
Xie W et al.Perinatal testosterone exposure potentiates vascular dysfunction by ERß suppression in endothelial progenitor cells.PLoS One 12:e0182945 (2017).
PubMed: 28809938
Korb E et al.Excess Translation of Epigenetic Regulators Contributes to Fragile X Syndrome and Is Alleviated by Brd4 Inhibition.Cell 170:1209-1223.e20 (2017).
PubMed: 28823556
Lee JY et al.Depletion of CTCF in Breast Cancer Cells Selectively Induces Cancer Cell Death via p53.J Cancer 8:2124-2131 (2017).
PubMed: 28819414
Zou Y et al.Prenatal levonorgestrel exposure induces autism-like behavior in offspring through ERß suppression in the amygdala.Mol Autism 8:46 (2017).
PubMed: 28824796
Ning B et al.USP26 functions as a negative regulator of cellular reprogramming by stabilising PRC1 complex components.Nat Commun 8:349 (2017).
PubMed: 28839133
Gokare P et al.P53 represses pyrimidine catabolic gene dihydropyrimidine dehydrogenase (DPYD) expression in response to thymidylate synthase (TS) targeting.Sci Rep 7:9711 (2017).
PubMed: 28851987
Lindsay CD et al.Efficacy of EZH2 inhibitory drugs in human papillomavirus-positive and human papillomavirus-negative oropharyngeal squamous cell carcinomas.Clin Epigenetics 9:95 (2017).
PubMed: 28878842
Gurrion C et al.Heterochromatin Reduction Correlates with the Increase of the KDM4B and KDM6A Demethylases and the Expression of Pericentromeric DNA during the Acquisition of a Transformed Phenotype.J Cancer 8:2866-2875 (2017).
PubMed: 28928876
Béguelin W et al.EZH2 enables germinal centre formation through epigenetic silencing of CDKN1A and an Rb-E2F1 feedback loop.Nat Commun 8:877 (2017).
PubMed: 29026085
Hamed M et al.Insights into interplay between rexinoid signaling and myogenic regulatory factor-associated chromatin state in myogenic differentiation.Nucleic Acids Res 45:11236-11248 (2017).
PubMed: 28981706
Soto DR et al.KDM6A addiction of cervical carcinoma cell lines is triggered by E7 and mediated by p21CIP1 suppression of replication stress.PLoS Pathog 13:e1006661 (2017).
PubMed: 28968467
Molitor J et al.Retrieving Chromatin Patterns from Deep Sequencing Data Using Correlation Functions.Biophys J 112:473-490 (2017).
PubMed: 28131315
Oittinen M et al.Polycomb Repressive Complex 2 Enacts Wnt Signaling in Intestinal Homeostasis and Contributes to the Instigation of Stemness in Diseases Entailing Epithelial Hyperplasia or Neoplasia.Stem Cells 35:445-457 (2017).
WB, ChIP
.
PubMed: 27570105
Ye Y et al.Chromatin remodeling during in vivo neural stem cells differentiating to neurons in early Drosophila embryos.Cell Death Differ 24:409-420 (2017).
ChIP
;
Drosophila melanogaster
.
PubMed: 27858939
Anderson L et al.Histone deacetylase inhibition modulates histone acetylation at gene promoter regions and affects genome-wide gene transcription in Schistosoma mansoni.PLoS Negl Trop Dis 11:e0005539 (2017).
WB, ChIP
;
Schistosoma mansoni
.
PubMed: 28406899
Di Giorgio E et al.The co-existence of transcriptional activator and transcriptional repressor MEF2 complexes influences tumor aggressiveness.PLoS Genet 13:e1006752 (2017).
ChIP
;
Human
.
PubMed: 28419090
Xun J et al.JMJD3 suppresses stem cell-like characteristics in breast cancer cells by downregulation of Oct4 independently of its demethylase activity.Oncotarget 8:21918-21929 (2017).
WB
;
Human
.
PubMed: 28423536
Ali T et al.Chromatin binding of Gcn5 in Drosophila is largely mediated by CP190.Nucleic Acids Res 45:2384-2395 (2017).
IP
;
Drosophila melanogaster
.
PubMed: 27903907
Pan G et al.PATZ1 down-regulates FADS1 by binding to rs174557 and is opposed by SP1/SREBP1c.Nucleic Acids Res 45:2408-2422 (2017).
ChIP
;
Human
.
PubMed: 27932482
Kim DH & Sung S The Binding Specificity of the PHD-Finger Domain of VIN3 Moderates Vernalization Response.Plant Physiol 173:1258-1268 (2017).
ChIP
;
Arabidopsis thaliana
.
PubMed: 27999085
Ohshima K et al.Argininosuccinate Synthase 1-Deficiency Enhances the Cell Sensitivity to Arginine through Decreased DEPTOR Expression in Endometrial Cancer.Sci Rep 7:45504 (2017).
ChIP
;
Human
.
PubMed: 28358054
Zhu XX et al.Jarid2 is essential for the maintenance of tumor initiating cells in bladder cancer.Oncotarget 8:24483-24490 (2017).
ChIP
;
Human
.
PubMed: 28445934
Jiao S et al.VGLL4 targets a TCF4-TEAD4 complex to coregulate Wnt and Hippo signalling in colorectal cancer.Nat Commun 8:14058 (2017).
WB
;
Human
.
PubMed: 28051067
Kim JJ et al.Optical High Content Nanoscopy of Epigenetic Marks Decodes Phenotypic Divergence in Stem Cells.Sci Rep 7:39406 (2017).
WB, Immunomicroscopy, IHC (PFA fixed)
;
Human
.
PubMed: 28051095
Seo W et al.Distinct requirement of Runx complexes for TCRß enhancer activation at distinct developmental stages.Sci Rep 7:41351 (2017).
ChIP
;
Mouse
.
PubMed: 28150718
Lo YH et al.Transcriptional Regulation by ATOH1 and its Target SPDEF in the Intestine.Cell Mol Gastroenterol Hepatol 3:51-71 (2017).
ChIP
;
Human
.
PubMed: 28174757
Wang XQ & Dostie J Reciprocal regulation of chromatin state and architecture by HOTAIRM1 contributes to temporal collinear HOXA gene activation.Nucleic Acids Res 45:1091-1104 (2017).
ChIP
;
Human
.
PubMed: 28180285
Nguyen K et al.Multiple Histone Lysine Methyltransferases Are Required for the Establishment and Maintenance of HIV-1 Latency.MBio 8:N/A (2017).
ChIP, WB
;
Human
.
PubMed: 28246360
Du Y et al.Nucleosome eviction along with H3K9ac deposition enhances Sox2 binding during human neuroectodermal commitment.Cell Death Differ 24:1121-1131 (2017).
CHIPseq
;
Human
.
PubMed: 28475175
Ridings-Figueroa R et al.The nuclear matrix protein CIZ1 facilitates localization of Xist RNA to the inactive X-chromosome territory.Genes Dev 31:876-888 (2017).
ICC/IF
;
Mouse
.
PubMed: 28546514
Kim ED et al.Spatio-temporal analysis of coding and long noncoding transcripts during maize endosperm development.Sci Rep 7:3838 (2017).
ChIP
.
PubMed: 28630499
Halaburková A et al.Histone deacetylase inhibitors potentiate photodynamic therapy in colon cancer cells marked by chromatin-mediated epigenetic regulation of CDKN1A.Clin Epigenetics 9:62 (2017).
ChIP
;
Human
.
PubMed: 28603560
Jensen GS et al.The RNA Polymerase-Associated Factor 1 Complex Is Required for Plant Touch Responses.J Exp Bot 68:499-511 (2017).
WB
.
PubMed: 28204553
Singh-Taylor A et al.NRSF-dependent epigenetic mechanisms contribute to programming of stress-sensitive neurons by neonatal experience, promoting resilience.Mol Psychiatry N/A:N/A (2017).
ChIP
.
PubMed: 28070121
Saayman SM et al.Long Non-coding RNA BGas Regulates the Cystic Fibrosis Transmembrane Conductance Regulator.Mol Ther 24:1351-7 (2016).
PubMed: 27434588
Gong C et al.BRCA1 positively regulates FOXO3 expression by restricting FOXO3 gene methylation and epigenetic silencing through targeting EZH2 in breast cancer.Oncogenesis 5:e214 (2016).
ChIP
.
PubMed: 27043660
Li D et al.Profiling Analysis of Histone Modifications and Gene Expression in Lewis Lung Carcinoma Murine Cells Resistant to Anti-VEGF Treatment.PLoS One 11:e0158214 (2016).
ChIP
.
PubMed: 27362259
Liu Y et al.Epigenetic profiles signify cell fate plasticity in unipotent spermatogonial stem and progenitor cells.Nat Commun 7:11275 (2016).
ChIP
.
PubMed: 27117588
Shi H et al.ASXL1 plays an important role in erythropoiesis.Sci Rep 6:28789 (2016).
ChIP
.
PubMed: 27352931
Wang W et al.PDX1 and ISL1 differentially coordinate with epigenetic modifications to regulate insulin gene expression in varied glucose concentrations.Mol Cell Endocrinol 428:38-48 (2016).
PubMed: 26994512
Rius SP et al.P1 Epigenetic Regulation in Leaves of High Altitude Maize Landraces: Effect of UV-B Radiation.Front Plant Sci 7:523 (2016).
ChIP
.
PubMed: 27148340
Douvaras P et al.Epigenetic Modulation of Human Induced Pluripotent Stem Cell Differentiation to Oligodendrocytes.Int J Mol Sci 17:N/A (2016).
WB
.
PubMed: 27110779
Mendiratta S et al.Interaction of the Chromatin Remodeling Protein hINO80 with DNA.PLoS One 11:e0159370 (2016).
Human
.
PubMed: 27428271
Boija A & Mannervik M Initiation of diverse epigenetic states during nuclear programming of the Drosophila body plan.Proc Natl Acad Sci U S A 113:8735-40 (2016).
PubMed: 27439862
Nandakumar V et al.Vorinostat differentially alters 3D nuclear structure of cancer and non-cancerous esophageal cells.Sci Rep 6:30593 (2016).
ICC/IF
;
Human
.
PubMed: 27503568
Chen Y et al.Suppression of PDCD4 mediated by the long non-coding RNA HOTAIR inhibits the proliferation and invasion of glioma cells.Oncol Lett 12:5170-5176 (2016).
ChIP
;
Human
.
PubMed: 28105224
Katsushima K et al.Targeting the Notch-regulated non-coding RNA TUG1 for glioma treatment.Nat Commun 7:13616 (2016).
ChIP
;
Human
.
PubMed: 27922002
Yapp C et al.H3K27me3 demethylases regulate in vitro chondrogenesis and chondrocyte activity in osteoarthritis.Arthritis Res Ther 18:158 (2016).
ICC/IF
;
Human
.
PubMed: 27388528
Venkatesh I et al.Epigenetic profiling reveals a developmental decrease in promoter accessibility during cortical maturation in vivo.Neuroepigenetics 8:19-26 (2016).
ChIP
;
Mouse
.
PubMed: 27990351
Heo SJ et al.Differentiation alters stem cell nuclear architecture, mechanics, and mechano-sensitivity.Elife 5:N/A (2016).
ICC/IF
;
Cow
.
PubMed: 27901466
Luizon MR et al.Genomic Characterization of Metformin Hepatic Response.PLoS Genet 12:e1006449 (2016).
CHIPseq
;
Human
.
PubMed: 27902686
Zhao E et al.Cancer mediates effector T cell dysfunction by targeting microRNAs and EZH2 via glycolysis restriction.Nat Immunol 17:95-103 (2016).
ChIP
;
Human
.
PubMed: 26523864
Navarro-Costa P et al.Early programming of the oocyte epigenome temporally controls late prophase I transcription and chromatin remodelling.Nat Commun 7:12331 (2016).
IF
;
Drosophila melanogaster
.
PubMed: 27507044
Wani AH et al.Chromatin topology is coupled to Polycomb group protein subnuclear organization.Nat Commun 7:10291 (2016).
ChIP
;
Drosophila melanogaster
.
PubMed: 26759081
Veith N et al.Mechanisms underlying epigenetic and transcriptional heterogeneity in Chinese hamster ovary (CHO) cell lines.BMC Biotechnol 16:6 (2016).
ChIP
.
PubMed: 26800878
Monte E et al.Reciprocal Regulation of the Cardiac Epigenome by Chromatin Structural Proteins Hmgb and Ctcf: IMPLICATIONS FOR TRANSCRIPTIONAL REGULATION.J Biol Chem 291:15428-46 (2016).
WB
;
Human
.
PubMed: 27226577
McKnight RA et al.Intrauterine growth restriction inhibits expression of eukaryotic elongation factor 2 kinase, a regulator of protein translation.Physiol Genomics 48:616-25 (2016).
ChIP
;
Rat
.
PubMed: 27317589
Park SJ et al.MacroH2A1 downregulation enhances the stem-like properties of bladder cancer cells by transactivation of Lin28B.Oncogene 35:1292-301 (2016).
ChIP
;
Human
.
PubMed: 26028027
Ancelin K et al.Maternal LSD1/KDM1A is an essential regulator of chromatin and transcription landscapes during zygotic genome activation.Elife 5:N/A (2016).
IF
.
PubMed: 26836306
Wang XQ & Dostie J Reciprocal regulation of chromatin state and architecture by HOTAIRM1 contributes to temporal collinear HOXA gene activation.Nucleic Acids Res N/A:N/A (2016).
ChIP
;
Human
.
PubMed: 27789700
Nagarsheth N et al.PRC2 Epigenetically Silences Th1-Type Chemokines to Suppress Effector T-Cell Trafficking in Colon Cancer.Cancer Res 76:275-82 (2016).
ChIP
.
PubMed: 26567139
Xia N et al.SENP1 Is a Crucial Regulator for Cell Senescence through DeSUMOylation of Bmi1.Sci Rep 6:34099 (2016).
PubMed: 27659494
Ye Y et al.Chromatin remodeling during the in vivo glial differentiation in early Drosophila embryos.Sci Rep 6:33422 (2016).
ChIP
.
PubMed: 27634414
Shih HT et al.dBRWD3 Regulates Tissue Overgrowth and Ectopic Gene Expression Caused by Polycomb Group Mutations.PLoS Genet 12:e1006262 (2016).
ChIP
;
Drosophila melanogaster
.
PubMed: 27588417
Xu C et al.MicroRNA-3196 is inhibited by H2AX phosphorylation and attenuates lung cancer cell apoptosis by downregulating PUMA.Oncotarget 7:77764-77776 (2016).
ChIP
;
Human
.
PubMed: 27780918
Rando G et al.Glucocorticoid receptor-PPARa axis in fetal mouse liver prepares neonates for milk lipid catabolism.Elife 5:N/A (2016).
ChIP
.
PubMed: 27367842
Wani S et al.Human SCP4 is a chromatin-associated CTD phosphatase and exhibits the dynamic translocation during erythroid differentiation.J Biochem 160:111-20 (2016).
PubMed: 26920047
Huang X et al.Imprinted gene OsFIE1 modulates rice seed development by influencing nutrient metabolism and modifying genome H3K27me3.Plant J 87:305-17 (2016).
PubMed: 27133784
Ray MK et al.CAT7 and cat7l Long Non-coding RNAs Tune Polycomb Repressive Complex 1 Function during Human and Zebrafish Development.J Biol Chem 291:19558-72 (2016).
PubMed: 27405765
Wang H et al.Induction of Germ Cell-like Cells from Porcine Induced Pluripotent Stem Cells.Sci Rep 6:27256 (2016).
ICC/IF
;
Pig
.
PubMed: 27264660
Meng S et al.Transdifferentiation Requires iNOS Activation: Role of RING1A S-Nitrosylation.Circ Res 119:e129-e138 (2016).
PubMed: 27623813
Meredith EK et al.An RNA matchmaker protein regulates the activity of the long noncoding RNA HOTAIR.RNA 22:995-1010 (2016).
PubMed: 27146324
Ueno K et al.Transition of differential histone H3 methylation in photoreceptors and other retinal cells during retinal differentiation.Sci Rep 6:29264 (2016).
ChIP
.
PubMed: 27377164
Akhade VS et al.
Mechanism of Wnt signaling induced down regulation of mrhl long non-coding RNA in mouse spermatogonial cells.
Nucleic Acids Res 44:387-401 (2016).
PubMed: 26446991
Vaidya H et al.Inactivation of the WNT5A Alternative Promoter B Is Associated with DNA Methylation and Histone Modification in Osteosarcoma Cell Lines U2OS and SaOS-2.PLoS One 11:e0151392 (2016).
ChIP
.
PubMed: 26978652
Zhang ZZ et al.Long non-coding RNA LINC00628 functions as a gastric cancer suppressor via long-range modulating the expression of cell cycle related genes.Sci Rep 6:27435 (2016).
ChIP
.
PubMed: 27272474
Elnfati AH et al.Nucleosomal chromatin in the mature sperm of Drosophila melanogaster.Genom Data 7:175-7 (2016).
PubMed: 26981400
Zhang X et al.Solar Simulated Ultraviolet Radiation Induces Global Histone Hypoacetylation in Human Keratinocytes.PLoS One 11:e0150175 (2016).
WB
.
PubMed: 26918332
Steiner LA et al.CTCF and CohesinSA-1 Mark Active Promoters and Boundaries of Repressive Chromatin Domains in Primary Human Erythroid Cells.PLoS One 11:e0155378 (2016).
ChIP
.
PubMed: 27219007
Ehrensberger AH et al.Retention of the Native Epigenome in Purified Mammalian Chromatin.PLoS One 10:e0133246 (2015).
ChIP
.
PubMed: 26248330
Takayama K et al.RUNX1, an androgen- and EZH2-regulated gene, has differential roles in AR-dependent and -independent prostate cancer.Oncotarget 6:2263-76 (2015).
PubMed: 25537508
Wei FZ et al.Epigenetic regulation of autophagy by the methyltransferase EZH2 through an MTOR-dependent pathway.Autophagy 11:2309-22 (2015).
PubMed: 26735435
Liao MY et al.Generation of an anti-EpCAM antibody and epigenetic regulation of EpCAM in colorectal cancer.Int J Oncol 46:1788-800 (2015).
PubMed: 25652097
Erokhin M et al.
Transcriptional read-through is not sufficient to induce an epigenetic switch in the silencing activity of Polycomb response elements.
Proc Natl Acad Sci U S A 112:14930-5 (2015).
ChIP
;
Drosophila melanogaster
.
PubMed: 26504232
Sekiya T et al.
Suppression of Th2 and Tfh immune reactions by Nr4a receptors in mature T reg cells.
J Exp Med 212:1623-40 (2015).
ChIP
;
Mouse
.
PubMed: 26304965
McNeal AS et al.
CDKN2B Loss Promotes Progression from Benign Melanocytic Nevus to Melanoma.
Cancer Discov 5:1072-85 (2015).
ChIP
.
PubMed: 26183406
Fukasawa R et al.
Mediator complex cooperatively regulates transcription of retinoic acid target genes with Polycomb Repressive Complex 2 during neuronal differentiation.
J Biochem 158:373-84 (2015).
PubMed: 26002960
Kozono D et al.Dynamic epigenetic regulation of glioblastoma tumorigenicity through LSD1 modulation of MYC expression.Proc Natl Acad Sci U S A 112:E4055-64 (2015).
ChIP
;
Mouse
.
PubMed: 26159421
Tripathy MK et al.H3K27 Demethylation at the Proviral Promoter Sensitizes Latent HIV to the Effects of Vorinostat in Ex Vivo Cultures of Resting CD4+ T Cells.J Virol 89:8392-405 (2015).
PubMed: 26041287
Grasso CS et al.Functionally defined therapeutic targets in diffuse intrinsic pontine glioma.Nat Med 21:555-9 (2015).
WB
;
Human
.
PubMed: 25939062
Van der Meulen J et al.The H3K27me3 demethylase UTX is a gender-specific tumor suppressor in T-cell acute lymphoblastic leukemia.Blood 125:13-21 (2015).
PubMed: 25320243
Zhang W et al.Pluripotent and Metabolic Features of Two Types of Porcine iPSCs Derived from Defined Mouse and Human ES Cell Culture Conditions.PLoS One 10:e0124562 (2015).
ICC
;
Pig
.
PubMed: 25893435
Kang SC et al.
Transcriptomic Profiling and H3K27me3 Distribution Reveal Both Demethylase-Dependent and Independent Regulation of Developmental Gene Transcription in Cell Differentiation.
PLoS One 10:e0135276 (2015).
WB
;
Human
.
PubMed: 26263556
Schertel C et al.
A large-scale, in vivo transcription factor screen defines bivalent chromatin as a key property of regulatory factors mediating Drosophila wing development.
Genome Res 25:514-23 (2015).
Drosophila melanogaster
.
PubMed: 25568052
Xiao X et al.GITR subverts Foxp3(+) Tregs to boost Th9 immunity through regulation of histone acetylation.Nat Commun 6:8266 (2015).
ChIP
;
Mouse
.
PubMed: 26365427
Sperber H et al.The metabolome regulates the epigenetic landscape during naive-to-primed human embryonic stem cell transition.Nat Cell Biol 17:1523-35 (2015).
WB
;
Human
.
PubMed: 26571212
Vandamme J et al.H3K23me2 is a new heterochromatic mark in Caenorhabditis elegans.Nucleic Acids Res 43:9694-710 (2015).
IF
;
Caenorhabditis elegans
.
PubMed: 26476455
Garruss AS & Fowler T Dataset of transcriptional landscape of B cell early activation.Genom Data 5:238-40 (2015).
CHIPseq
;
Mouse
.
PubMed: 26484262
Hatanaka Y et al.Histone chaperone CAF-1 mediates repressive histone modifications to protect preimplantation mouse embryos from endogenous retrotransposons.Proc Natl Acad Sci U S A 112:14641-6 (2015).
ChIP, ICC/IF
;
Mouse
.
PubMed: 26546670
Philip P et al.CBP binding outside of promoters and enhancers in Drosophila melanogaster.Epigenetics Chromatin 8:48 (2015).
Drosophila melanogaster
.
PubMed: 26604986
Geeven G et al.Local compartment changes and regulatory landscape alterations in histone H1-depleted cells.Genome Biol 16:289 (2015).
CHIPseq
;
Mouse
.
PubMed: 26700097
Fowler T et al.Divergence of transcriptional landscape occurs early in B cell activation.Epigenetics Chromatin 8:20 (2015).
CHIPseq
.
PubMed: 25987903
Karamitros D et al.Geminin deletion increases the number of fetal hematopoietic stem cells by affecting the expression of key transcription factors.Development 142:70-81 (2015).
ChIP
;
Human
.
PubMed: 25516969
Zhang H et al.PLK1 and HOTAIR Accelerate Proteasomal Degradation of SUZ12 and ZNF198 during Hepatitis B Virus-Induced Liver Carcinogenesis.Cancer Res 75:2363-74 (2015).
ChIP
.
PubMed: 25855382
Sun C et al.Epigenetic regulation of histone modifications and Gata6 gene expression induced by maternal diet in mouse embryoid bodies in a model of developmental programming.BMC Dev Biol 15:3 (2015).
ChIP
;
Mouse
.
PubMed: 25609498
Balasubramani A et al.Cancer-associated ASXL1 mutations may act as gain-of-function mutations of the ASXL1-BAP1 complex.Nat Commun 6:7307 (2015).
ICC
;
Mouse
.
PubMed: 26095772
Maekawa S et al.Analysis of RNA decay factor mediated RNA stability contributions on RNA abundance.BMC Genomics 16:154 (2015).
ChIP
;
Human
.
PubMed: 25879614
Singh AM et al.Cell-Cycle Control of Bivalent Epigenetic Domains Regulates the Exit from Pluripotency.Stem Cell Reports 5:323-36 (2015).
ChIP
;
Human
.
PubMed: 26278042
Yao X et al.The Mediator subunit MED23 couples H2B mono-ubiquitination to transcriptional control and cell fate determination.EMBO J 34:2885-902 (2015).
WB
.
PubMed: 26330467
LaFave LM et al.Loss of BAP1 function leads to EZH2-dependent transformation.Nat Med 21:1344-9 (2015).
WB, ChIP
.
PubMed: 26437366
Wurm S et al.Terminal epidermal differentiation is regulated by the interaction of Fra-2/AP-1 with Ezh2 and ERK1/2.Genes Dev 29:144-56 (2015).
ChIP
;
Mouse
.
PubMed: 25547114
Müller-Kuller U et al.A minimal ubiquitous chromatin opening element (UCOE) effectively prevents silencing of juxtaposed heterologous promoters by epigenetic remodeling in multipotent and pluripotent stem cells.Nucleic Acids Res 43:1577-92 (2015).
ChIP
.
PubMed: 25605798
Navarro JM et al.Site- and allele-specific polycomb dysregulation in T-cell leukaemia.Nat Commun 6:6094 (2015).
ChIP
.
PubMed: 25615415
Koo JW et al.Epigenetic basis of opiate suppression of Bdnf gene expression in the ventral tegmental area.Nat Neurosci 18:415-22 (2015).
ChIP
;
Rat
.
PubMed: 25643298
Xiao T et al.Long Noncoding RNA ADINR Regulates Adipogenesis by Transcriptionally Activating C/EBPa.Stem Cell Reports 5:856-65 (2015).
ChIP
;
Human
.
PubMed: 26489893
Liu C et al.PRC2 regulates RNA polymerase III transcribed non-translated RNA gene transcription through EZH2 and SUZ12 interaction with TFIIIC complex.Nucleic Acids Res 43:6270-84 (2015).
WB
;
Human
.
PubMed: 26038315
Tran PV et al.Fetal iron deficiency induces chromatin remodeling at the Bdnf locus in adult rat hippocampus.Am J Physiol Regul Integr Comp Physiol 308:R276-82 (2015).
ChIP
;
Rat
.
PubMed: 25519736
Fufa TD et al.Genomic analysis reveals distinct mechanisms and functional classes of SOX10-regulated genes in melanocytes.Hum Mol Genet 24:5433-50 (2015).
ChIP
;
Mouse
.
PubMed: 26206884
Kassab MA et al.Gene Silencing and Activation of Human Papillomavirus 18 Is Modulated by Sense Promoter Associated RNA in Bidirectionally Transcribed Long Control Region.PLoS One 10:e0128416 (2015).
ChIP
;
Human
.
PubMed: 26047143
Porter LF et al.
A role for repressive complexes and H3K9 di-methylation in PRDM5-associated brittle cornea syndrome.
Hum Mol Genet 24:6565-79 (2015).
WB
;
Human
.
PubMed: 26395458
Rothbart SB et al.An Interactive Database for the Assessment of Histone Antibody Specificity.Mol Cell 59:502-11 (2015).
ChIP
;
Mouse
.
PubMed: 26212453
Wan J et al.
PCAF-primed EZH2 acetylation regulates its stability and promotes lung adenocarcinoma progression.
Nucleic Acids Res 43:3591-604 (2015).
WB
;
Human
.
PubMed: 25800736
Nordström L et al.DNA methylation and histone modifications regulate SOX11 expression in lymphoid and solid cancer cells.BMC Cancer 15:273 (2015).
ChIP
;
Human
.
PubMed: 25880212
Guo Z et al.Global epigenomic analysis indicates that epialleles contribute to Allele-specific expression via Allele-specific histone modifications in hybrid rice.BMC Genomics 16:232 (2015).
CHIPseq
;
Rice
.
PubMed: 25886904
Xu G et al.The histone methyltransferase Smyd2 is a negative regulator of macrophage activation by suppressing interleukin 6 (IL-6) and tumor necrosis factor a (TNF-a) production.J Biol Chem 290:5414-23 (2015).
ChIP
;
Mouse
.
PubMed: 25583990
Liu Y et al.Histone lysine methyltransferase Ezh1 promotes TLR-triggered inflammatory cytokine production by suppressing Tollip.J Immunol 194:2838-46 (2015).
IP
;
Mouse
.
PubMed: 25687760
Cook KD et al.T Follicular Helper Cell-Dependent Clearance of a Persistent Virus Infection Requires T Cell Expression of the Histone Demethylase UTX.Immunity 43:703-14 (2015).
PubMed: 26431949
Li Q et al.KDM6B induces epithelial-mesenchymal transition and enhances clear cell renal cell carcinoma metastasis through the activation of SLUG.Int J Clin Exp Pathol 8:6334-44 (2015).
PubMed: 26261509
Lu S et al.The transcription factor c-Fos coordinates with histone lysine-specific demethylase 2A to activate the expression of cyclooxygenase-2.Oncotarget 6:34704-17 (2015).
WB
.
PubMed: 26430963
Vlachogiannis G et al.The Dnmt3L ADD Domain Controls Cytosine Methylation Establishment during Spermatogenesis.Cell Rep N/A:N/A (2015).
PubMed: 25683717
Reeder JE et al.HIV Tat controls RNA Polymerase II and the epigenetic landscape to transcriptionally reprogram target immune cells.Elife 4:N/A (2015).
ChIP
.
PubMed: 26488441
Erfani P et al.EGFR promoter exhibits dynamic histone modifications and binding of ASH2L and P300 in human germinal matrix and gliomas.Epigenetics 10:496-507 (2015).
PubMed: 25996283
Sequeira-Mendes J et al.The Functional Topography of the Arabidopsis Genome Is Organized in a Reduced Number of Linear Motifs of Chromatin States.Plant Cell 26:2351-2366 (2014).
ChIP/Chip
;
Arabidopsis thaliana
.
PubMed: 24934173
Deneberg S et al.microRNA-34b/c on chromosome 11q23 is aberrantly methylated in chronic lymphocytic leukemia.Epigenetics 9:910-7 (2014).
PubMed: 24686393
Ahsan S et al.Increased 5-hydroxymethylcytosine and decreased 5-methylcytosine are indicators of global epigenetic dysregulation in diffuse intrinsic pontine glioma.Acta Neuropathol Commun 2:59 (2014).
IHC
.
PubMed: 24894482
Benard A et al.Chromatin status of apoptosis genes correlates with sensitivity to chemo-, immune- and radiation therapy in colorectal cancer cell lines.Apoptosis 19:1769-78 (2014).
PubMed: 25292014
Song G et al.The phenotypic predisposition of the parent in F1 hybrid is correlated with transcriptome preference of the positive general combining ability parent.BMC Genomics 15:297 (2014).
ChIP
.
PubMed: 24755044
Zhu X et al.Identification of functional cooperative mutations of SETD2 in human acute leukemia.Nat Genet 46:287-93 (2014).
PubMed: 24509477
Shen H et al.BMI1 reprogrammes histone acetylation and enhances c-fos pathway via directly binding to Zmym3 in malignant myeloid progression.J Cell Mol Med 18:1004-17 (2014).
ChIP
.
PubMed: 24571310
Mak KS et al.Repression of chimeric transcripts emanating from endogenous retrotransposons by a sequence-specific transcription factor.Genome Biol 15:R58 (2014).
ChIP
;
Mouse
.
PubMed: 24946810
Yamamoto K et al.Loss of histone demethylase KDM6B enhances aggressiveness of pancreatic cancer through downregulation of C/EBPa.Carcinogenesis 35:2404-14 (2014).
WB
;
Human
.
PubMed: 24947179
Kumari D & Usdin K
Polycomb group complexes are recruited to reactivated FMR1 alleles in Fragile X syndrome in response to FMR1 transcription.
Hum Mol Genet 23:6575-83 (2014).
ChIP
.
PubMed: 25055869
Siegle JM et al.SOX2 is a cancer-specific regulator of tumour initiating potential in cutaneous squamous cell carcinoma.Nat Commun 5:4511 (2014).
ChIP
.
PubMed: 25077433
Ullius A et al.The interaction of MYC with the trithorax protein ASH2L promotes gene transcription by regulating H3K27 modification.Nucleic Acids Res : (2014).
PubMed: 24782528
Creppe C et al.A Cbx8-containing polycomb complex facilitates the transition to gene activation during ES cell differentiation.PLoS Genet 10:e1004851 (2014).
PubMed: 25500566
Horrell SA & Chalker DL LIA4 encodes a chromoshadow domain protein required for genomewide DNA rearrangements in Tetrahymena thermophila.Eukaryot Cell 13:1300-11 (2014).
PubMed: 25084866
Suzuki A et al.Aberrant transcriptional regulations in cancers: genome, transcriptome and epigenome analysis of lung adenocarcinoma cell lines.Nucleic Acids Res 42:13557-72 (2014).
CHIPseq
;
Human
.
PubMed: 25378332
Huh YH & Sherley JL Decreased H3K27 and H3K4 trimethylation on mortal chromosomes in distributed stem cells.Cell Death Dis 5:e1554 (2014).
PubMed: 25476902
Dimitrova N et al.LincRNA-p21 activates p21 in cis to promote Polycomb target gene expression and to enforce the G1/S checkpoint.Mol Cell 54:777-90 (2014).
WB, ChIP
.
PubMed: 24857549
Shin JH & Chekanova JA Arabidopsis RRP6L1 and RRP6L2 function in FLOWERING LOCUS C silencing via regulation of antisense RNA synthesis.PLoS Genet 10:e1004612 (2014).
ChIP
;
Arabidopsis thaliana
.
PubMed: 25211139
Benard A et al.Prognostic Value of Polycomb Proteins EZH2, BMI1 and SUZ12 and Histone Modification H3K27me3 in Colorectal Cancer.PLoS One 9:e108265 (2014).
WB, IHC-P
;
Human
.
PubMed: 25243792
Wang Z et al.Epigenetic reprogramming of human lung cancer cells with the extract of bovine parthenogenetic oocytes.J Cell Mol Med 18:1807-15 (2014).
ChIP
.
PubMed: 24889513
Darrow EM et al.A region of euchromatin coincides with an extensive tandem repeat on the mouse (Mus musculus) inactive X chromosome.Chromosome Res 22:335-50 (2014).
Mouse
.
PubMed: 24821208
Gaudichon J et al.Deazaneplanocin a is a promising drug to kill multiple myeloma cells in their niche.PLoS One 9:e107009 (2014).
PubMed: 25255316
Chu CS et al.O-GlcNAcylation regulates EZH2 protein stability and function.Proc Natl Acad Sci U S A 111:1355-60 (2014).
PubMed: 24474760
Gonzalez ME et al.EZH2 expands breast stem cells through activation of NOTCH1 signaling.Proc Natl Acad Sci U S A 111:3098-103 (2014).
WB
;
Human
.
PubMed: 24516139
Yamaguchi N et al.PROTOCOLS: Chromatin Immunoprecipitation from Arabidopsis Tissues.Arabidopsis Book 12:e0170 (2014).
ChIP
;
Arabidopsis thaliana
.
PubMed: 24653666
Iida A et al.Histone demethylase Jmjd3 is required for the development of subsets of retinal bipolar cells.Proc Natl Acad Sci U S A 111:3751-6 (2014).
ChIP
.
PubMed: 24572572
Convertini P et al.Sudemycin E influences alternative splicing and changes chromatin modifications.Nucleic Acids Res 42:4947-61 (2014).
ChIP
;
Human
.
PubMed: 24623796
Puttagunta R et al.PCAF-dependent epigenetic changes promote axonal regeneration in the central nervous system.Nat Commun 5:3527 (2014).
PubMed: 24686445
Girard N et al.3-Deazaneplanocin A (DZNep), an inhibitor of the histone methyltransferase EZH2, induces apoptosis and reduces cell migration in chondrosarcoma cells.PLoS One 9:e98176 (2014).
WB
;
Human
.
PubMed: 24852755
Shin J et al.RLIM is dispensable for X-chromosome inactivation in the mouse embryonic epiblast.Nature 511:86-9 (2014).
Mouse
.
PubMed: 24870238
Orsi GA et al.High-resolution mapping defines the cooperative architecture of Polycomb response elements.Genome Res 24:809-20 (2014).
IP
.
PubMed: 24668908
de Assuncao TM et al.New Role for Kruppel-like Factor 14 as a Transcriptional Activator Involved in the Generation of Signaling Lipids.J Biol Chem 289:15798-15809 (2014).
ChIP
;
Human
.
PubMed: 24759103
Roy D et al.Differential Acetylation of Histone H3 at the Regulatory Region of OsDREB1b Promoter Facilitates Chromatin Remodelling and Transcription Activation during Cold Stress.PLoS One 9:e100343 (2014).
ChIP
;
Rice
.
PubMed: 24940877
Lebailly B et al.Linking the circadian rhythm gene Arntl2 to interleukin 21 expression in type 1 diabetes.Diabetes 63:2148-57 (2014).
PubMed: 24520124
Yang X et al.Histone modifications are associated with ?9-tetrahydrocannabinol-mediated alterations in antigen-specific T cell responses.J Biol Chem 289:18707-18 (2014).
ChIP
;
Mouse
.
PubMed: 24841204
Rahat B et al.Epigenetic mechanisms regulate placental c-myc and hTERT in normal and pathological pregnancies; c-myc as a novel fetal DNA epigenetic marker for pre-eclampsia.Mol Hum Reprod N/A:N/A (2014).
Human
.
PubMed: 25024139
Korenjak M et al.dREAM co-operates with insulator-binding proteins and regulates expression at divergently paired genes.Nucleic Acids Res 42:8939-53 (2014).
ChIP
.
PubMed: 25053843
Ito S et al.Loss of neuronal 3D chromatin organization causes transcriptional and behavioural deficits related to serotonergic dysfunction.Nat Commun 5:4450 (2014).
PubMed: 25034090
Kahn TG et al.Combinatorial interactions are required for the efficient recruitment of pho repressive complex (PhoRC) to polycomb response elements.PLoS Genet 10:e1004495 (2014).
PubMed: 25010632
Matsumoto K et al.Construction of mate pair full-length cDNAs libraries and characterization of transcriptional start sites and termination sites.Nucleic Acids Res N/A:N/A (2014).
ChIP
;
Human
.
PubMed: 25034687
Jutooru I et al.Mechanism of action of phenethylisothiocyanate and other reactive oxygen species-inducing anticancer agents.Mol Cell Biol 34:2382-95 (2014).
PubMed: 24732804
Jermann P et al.Short sequences can efficiently recruit histone H3 lysine 27 trimethylation in the absence of enhancer activity and DNA methylation.Proc Natl Acad Sci U S A 111:E3415-21 (2014).
ChIP
.
PubMed: 25092339
Shpargel KB et al.KDM6 demethylase independent loss of histone H3 lysine 27 trimethylation during early embryonic development.PLoS Genet 10:e1004507 (2014).
ChIP
;
Mouse
.
PubMed: 25101834
Ho JW et al.Comparative analysis of metazoan chromatin organization.Nature 512:449-52 (2014).
PubMed: 25164756
Ntziachristos P et al.Contrasting roles of histone 3 lysine 27 demethylases in acute lymphoblastic leukaemia.Nature N/A:N/A (2014).
PubMed: 25132549
Whitworth DJ et al.Generation and characterization of leukemia inhibitory factor-dependent equine induced pluripotent stem cells from adult dermal fibroblasts.Stem Cells Dev 23:1515-23 (2014).
PubMed: 24555755
Jiang Y et al.Xist deficiency and disorders of X-inactivation in rabbit embryonic stem cells can be rescued by transcription-factor-mediated conversion.Stem Cells Dev 23:2283-96 (2014).
PubMed: 24805295
Harms MJ et al.Prdm16 is required for the maintenance of brown adipocyte identity and function in adult mice.Cell Metab 19:593-604 (2014).
PubMed: 24703692
Izzo F et al.Progesterone receptor activation downregulates GATA3 by transcriptional repression and increased protein turnover promoting breast tumor growth.Breast Cancer Res 16:491 (2014).
PubMed: 25479686
Himeda CL et al.Myogenic enhancers regulate expression of the facioscapulohumeral muscular dystrophy-associated DUX4 gene.Mol Cell Biol 34:1942-55 (2014).
PubMed: 24636994
Walsh CA et al.Global gene repression by the steroid receptor coactivator SRC-1 promotes oncogenesis.Cancer Res 74:2533-44 (2014).
PubMed: 24648347
Whitworth DJ et al.Derivation of mesenchymal stromal cells from canine induced pluripotent stem cells by inhibition of the TGFß/activin signaling pathway.Stem Cells Dev 23:3021-33 (2014).
ICC
.
PubMed: 25055193
Lybæk H et al.RevSex duplication-induced and sex-related differences in the SOX9 regulatory region chromatin landscape in human fibroblasts.Epigenetics 9:416-27 (2014).
ChIP
.
PubMed: 24351654
Benard A et al.Epigenetic status of LINE-1 predicts clinical outcome in early-stage rectal cancer.Br J Cancer 109:3073-83 (2013).
PubMed: 24220694
Shieh AW & Chalker DL LIA5 Is Required for Nuclear Reorganization and Programmed DNA Rearrangements Occurring during Tetrahymena Macronuclear Differentiation.PLoS One 8:e75337 (2013).
PubMed: 24069402
van Rensburg R et al.Chromatin structure of two genomic sites for targeted transgene integration in induced pluripotent stem cells and hematopoietic stem cells.Gene Ther 20:201-14 (2013).
ChIP
.
PubMed: 22436965
Robison AJ et al.Fluoxetine Epigenetically Alters the CaMKIIa Promoter in Nucleus Accumbens to Regulate ?FosB Binding and Antidepressant Effects.Neuropsychopharmacology : (2013).
PubMed: 24240473
Singh SK et al.Sirt1 ablation promotes stress-induced loss of epigenetic and genomic hematopoietic stem and progenitor cell maintenance.J Exp Med 210:987-1001 (2013).
ChIP
;
Mouse
.
PubMed: 23630229
Tsuchiya T & Eulgem T Mutations in EDM2 selectively affect silencing states of transposons and induce plant developmental plasticity.Sci Rep 3:1701 (2013).
ChIP
;
Arabidopsis thaliana
.
PubMed: 23609044
Nagel S et al.Ectopic expression of homeobox gene NKX2-1 in diffuse large B-cell lymphoma is mediated by aberrant chromatin modifications.PLoS One 8:e61447 (2013).
ChIP
;
Human
.
PubMed: 23637834
Jiao B et al.8-CPT-cAMP/all-trans retinoic acid targets t(11;17) acute promyelocytic leukemia through enhanced cell differentiation and PLZF/RARa degradation.Proc Natl Acad Sci U S A 110:3495-500 (2013).
ChIP
;
Mouse
.
PubMed: 23382200
Melas PA et al.Allele-specific programming of Npy and epigenetic effects of physical activity in a genetic model of depression.Transl Psychiatry 3:e255 (2013).
ChIP
;
Rat
.
PubMed: 23652932
Komers R et al.Epigenetic changes in renal genes dysregulated in mouse and rat models of type 1 diabetes.Lab Invest 93:543-52 (2013).
Mouse
.
PubMed: 23508046
Wang L et al.BRCA1 is a negative modulator of the PRC2 complex.EMBO J 32:1584-97 (2013).
Human
.
PubMed: 23624935
Olsen JR et al.p63 attenuates epithelial to mesenchymal potential in an experimental prostate cell model.PLoS One 8:e62547 (2013).
WB
.
PubMed: 23658742
Zawistowski JS et al.MicroRNA 9-3p targets ß1 integrin to sensitize claudin-low breast cancer cells to MEK inhibition.Mol Cell Biol 33:2260-74 (2013).
PubMed: 23530058
Bengani H et al.Identification and Validation of a Putative Polycomb Responsive Element in the Human Genome.PLoS One 8:e67217 (2013).
PubMed: 23805300
Schaaf CA et al.Cohesin and polycomb proteins functionally interact to control transcription at silenced and active genes.PLoS Genet 9:e1003560 (2013).
ChIP/Chip
.
PubMed: 23818863
Kerl K et al.The histone deacetylase inhibitor SAHA acts in synergism with fenretinide and doxorubicin to control growth of rhabdoid tumor cells.BMC Cancer 13:286 (2013).
WB
.
PubMed: 23764045
Chan PK et al.Heterochromatinization induced by GAA-repeat hyperexpansion in Friedreich's ataxia can be reduced upon HDAC inhibition by vitamin B3.Hum Mol Genet N/A:N/A (2013).
PubMed: 23474817
Saha S et al.Polycomblike protein PHF1b: a transcriptional sensor for GABA receptor activity.BMC Pharmacol Toxicol 14:37 (2013).
PubMed: 23879974
Holdt LM et al.Alu elements in ANRIL non-coding RNA at chromosome 9p21 modulate atherogenic cell functions through trans-regulation of gene networks.PLoS Genet 9:e1003588 (2013).
PubMed: 23861667
Woo CJ et al.Variable requirements for DNA-binding proteins at polycomb-dependent repressive regions in human HOX clusters.Mol Cell Biol 33:3274-85 (2013).
PubMed: 23775117
Wang Q et al.The reprogrammed pancreatic progenitor-like intermediate state of hepatic cells is more susceptible to pancreatic beta cell differentiation.J Cell Sci 126:3638-48 (2013).
Rat
.
PubMed: 23750005
Beckedorff FC et al.The intronic long noncoding RNA ANRASSF1 recruits PRC2 to the RASSF1A promoter, reducing the expression of RASSF1A and increasing cell proliferation.PLoS Genet 9:e1003705 (2013).
ChIP
.
PubMed: 23990798
Sugathan A & Waxman DJ Genome-wide analysis of chromatin states reveals distinct mechanisms of sex-dependent gene regulation in male and female mouse liver.Mol Cell Biol 33:3594-610 (2013).
PubMed: 23836885
Tsuchiya T & Eulgem T An alternative polyadenylation mechanism coopted to the Arabidopsis RPP7 gene through intronic retrotransposon domestication.Proc Natl Acad Sci U S A 110:E3535-43 (2013).
PubMed: 23940361
Jia J et al.An integrated transcriptome and epigenome analysis identifies a novel candidate gene for pancreatic cancer.BMC Med Genomics 6:33 (2013).
ChIP
;
Human
.
PubMed: 24053169
Attema JL et al.Identification of an Enhancer That Increases miR-200b~200a~429 Gene Expression in Breast Cancer Cells.PLoS One 8:e75517 (2013).
ChIP
.
PubMed: 24086551
Singh A et al.Long-term suppression of HIV-1C virus production in human peripheral blood mononuclear cells by LTR heterochromatization with a short double-stranded RNA.J Antimicrob Chemother N/A:N/A (2013).
IP
.
PubMed: 24022068
Lesch BJ et al.A set of genes critical to development is epigenetically poised in mouse germ cells from fetal stages through completion of meiosis.Proc Natl Acad Sci U S A 110:16061-6 (2013).
CHIPseq
;
Mouse
.
PubMed: 24043772
Vasanthi D et al.A functionally conserved Polycomb response element from mouse HoxD complex responds to heterochromatin factors.Sci Rep 3:3011 (2013).
ChIP
.
PubMed: 24145990
Li J et al.EZH2-mediated H3K27 trimethylation mediates neurodegeneration in ataxia-telangiectasia.Nat Neurosci 16:1745-53 (2013).
PubMed: 24162653
Wang T et al.The control of hematopoietic stem cell maintenance, self-renewal, and differentiation by Mysm1-mediated epigenetic regulation.Blood 122:2812-22 (2013).
ChIP
;
Mouse
.
PubMed: 24014243
Bender S et al.Reduced H3K27me3 and DNA Hypomethylation Are Major Drivers of Gene Expression in K27M Mutant Pediatric High-Grade Gliomas.Cancer Cell 24:660-72 (2013).
WB
;
Human
.
PubMed: 24183680
Rousseau M et al.Hox in motion: tracking HoxA cluster conformation during differentiation.Nucleic Acids Res N/A:N/A (2013).
Human
.
PubMed: 24174538
Zhou Q et al.The epigenome of evolving Drosophila neo-sex chromosomes: dosage compensation and heterochromatin formation.PLoS Biol 11:e1001711 (2013).
CHIPseq
.
PubMed: 24265597
Silva-Sousa R & Casacuberta E The JIL-1 kinase affects telomere expression in the different telomere domains of Drosophila.PLoS One 8:e81543 (2013).
ChIP
;
Drosophila melanogaster
.
PubMed: 24244743
Rosolowski M et al.Massive transcriptional perturbation in subgroups of diffuse large B-cell lymphomas.PLoS One 8:e76287 (2013).
IHC-P
;
Human
.
PubMed: 24223701
Kim DH et al.Histone H3K27 trimethylation inhibits H3 binding and function of SET1-like H3K4 methyltransferase complexes.Mol Cell Biol 33:4936-46 (2013).
PubMed: 24126056
Ishibashi K et al.Nuclear ErbB4 signaling through H3K9me3 is antagonized by EGFR-activated c-Src.J Cell Sci 126:625-37 (2013).
PubMed: 23230144
Eberhart A et al.Epigenetics of eu- and heterochromatin in inverted and conventional nuclei from mouse retina.Chromosome Res 21:535-54 (2013).
IHC-Fr
;
Mouse
.
PubMed: 23996328
Kashyap V et al.RAR? is essential for retinoic acid induced chromatin remodeling and transcriptional activation in embryonic stem cells.J Cell Sci 126:999-1008 (2013).
ChIP/Chip
;
Mouse
.
PubMed: 23264745
Javaid S et al.Dynamic chromatin modification sustains epithelial-mesenchymal transition following inducible expression of Snail-1.Cell Rep 5:1679-89 (2013).
ChIP
;
Human
.
PubMed: 24360956
Moore HM et al.EZH2 inhibition decreases p38 signaling and suppresses breast cancer motility and metastasis.Breast Cancer Res Treat 138:741-52 (2013).
WB
;
Human
.
PubMed: 23539298
Mazzoni EO et al.Saltatory remodeling of Hox chromatin in response to rostrocaudal patterning signals.Nat Neurosci 16:1191-8 (2013).
ChIP/Chip
.
PubMed: 23955559
Konze KD et al.An orally bioavailable chemical probe of the Lysine Methyltransferases EZH2 and EZH1.ACS Chem Biol 8:1324-34 (2013).
ChIP
;
Human
.
PubMed: 23614352
Lyu T et al.Expression and epigenetic regulation of angiogenesis-related factors during dormancy and recurrent growth of ovarian carcinoma.Epigenetics 8:1330-46 (2013).
Human
.
PubMed: 24135786
Haffner MC et al.Tight correlation of 5-hydroxymethylcytosine and Polycomb marks in health and disease.Cell Cycle 12:1835-41 (2013).
IHC-P
;
Human
.
PubMed: 23676216
Gomez D et al.Detection of histone modifications at specific gene loci in single cells in histological sections.Nat Methods 10:171-7 (2013).
ICC/IF
.
PubMed: 23314172
Morrison PJ et al.Th17-cell plasticity in Helicobacter hepaticus-induced intestinal inflammation.Mucosal Immunol 6:1143-56 (2013).
ChIP
;
Mouse
.
PubMed: 23462910
Moison C et al.DNA methylation associated with polycomb repression in retinoic acid receptor ß silencing.FASEB J 27:1468-78 (2013).
PubMed: 23299856
Williams A et al.Hypersensitive site 6 of the Th2 locus control region is essential for Th2 cytokine expression.Proc Natl Acad Sci U S A 110:6955-60 (2013).
ChIP
.
PubMed: 23569250
Schang AL et al.GATA2-induced silencing and LIM-homeodomain protein-induced activation are mediated by a bi-functional response element in the rat GnRH receptor gene.Mol Endocrinol 27:74-91 (2013).
PubMed: 23211524
Connolly LR et al.The Fusarium graminearum histone H3 K27 methyltransferase KMT6 regulates development and expression of secondary metabolite gene clusters.PLoS Genet 9:e1003916 (2013).
WB
.
PubMed: 24204317
Brouwer JR et al.Transcriptionally Repressive Chromatin Remodelling and CpG Methylation in the Presence of Expanded CTG-Repeats at the DM1 Locus.J Nucleic Acids 2013:567435 (2013).
ChIP
.
PubMed: 24455202
Zhang X et al.Histone deacetylase inhibition downregulates collagen 3A1 in fibrotic lung fibroblasts.Int J Mol Sci 14:19605-17 (2013).
WB
.
PubMed: 24084714
Min H et al.Hoxc gene collinear expression and epigenetic modifications established during embryogenesis are maintained until after birth.Int J Biol Sci 9:960-5 (2013).
ChIP
.
PubMed: 24155669
Lin WC et al.The role of Sp1 and EZH2 in the regulation of LMX1A in cervical cancer cells.Biochim Biophys Acta 1833:3206-3217 (2013).
PubMed: 24018208
Dreger H et al.Epigenetic regulation of cell adhesion and communication by enhancer of zeste homolog 2 in human endothelial cells.Hypertension 60:1176-83 (2012).
PubMed: 22966008
Pasque V et al.Histone variant macroH2A marks embryonic differentiation in vivo and acts as an epigenetic barrier to induced pluripotency.J Cell Sci 125:6094-104 (2012).
ICC
.
PubMed: 23077180
Shinojima T et al.Heterogeneous epigenetic regulation of TIMP3 in prostate cancer.Epigenetics 7:1279-89 (2012).
PubMed: 23023649
Ramírez J et al.MBD2 and multiple domains of CHD4 are required for transcriptional repression by Mi-2/NuRD complexes.Mol Cell Biol 32:5078-88 (2012).
PubMed: 23071088
Zhang Y et al.Dynamic, sex-differential STAT5 and BCL6 binding to sex-biased, growth hormone-regulated genes in adult mouse liver.Mol Cell Biol 32:880-96 (2012).
PubMed: 22158971
Panigrahi SK et al.Sp1 transcription factor and GATA1 cis-acting elements modulate testis-specific expression of mouse cyclin A1.PLoS One 7:e47862 (2012).
ChIP
.
PubMed: 23112860
Tyan SW et al.Breast cancer cells induce stromal fibroblasts to secrete ADAMTS1 for cancer invasion through an epigenetic change.PLoS One 7:e35128 (2012).
ChIP
.
PubMed: 22514714
Balasubramanian D et al.H3K4me3 inversely correlates with DNA methylation at a large class of non-CpG-island-containing start sites.Genome Med 4:47 (2012).
ChIP
.
PubMed: 22640407
Cherrington BD et al.Potential role for PAD2 in gene regulation in breast cancer cells.PLoS One 7:e41242 (2012).
ChIP
.
PubMed: 22911765
Orlando DA et al.CpG island structure and trithorax/polycomb chromatin domains in human cells.Genomics 100:320-6 (2012).
PubMed: 22819920
Hopkin AS et al.GRHL3/GET1 and trithorax group members collaborate to activate the epidermal progenitor differentiation program.PLoS Genet 8:e1002829 (2012).
ChIP
.
PubMed: 22829784
Jin B et al.Linking DNA methyltransferases to epigenetic marks and nucleosome structure genome-wide in human tumor cells.Cell Rep 2:1411-24 (2012).
PubMed: 23177624
Jia J et al.Regulation of pluripotency and self- renewal of ESCs through epigenetic-threshold modulation and mRNA pruning.Cell 151:576-89 (2012).
PubMed: 23101626
Pinter SF et al.Spreading of X chromosome inactivation via a hierarchy of defined Polycomb stations.Genome Res 22:1864-76 (2012).
PubMed: 22948768
Lee J et al.Genomic analysis of hepatic farnesoid X receptor binding sites reveals altered binding in obesity and direct gene repression by farnesoid X receptor in mice.Hepatology 56:108-17 (2012).
ChIP
.
PubMed: 22278336
Holmqvist PH et al.Preferential Genome Targeting of the CBP Co-Activator by Rel and Smad Proteins in Early Drosophila melanogaster Embryos.PLoS Genet 8:e1002769 (2012).
ChIP
.
PubMed: 22737084
Fedoriw AM et al.Nucleolar association and transcriptional inhibition through 5S rDNA in mammals.PLoS Genet 8:e1002468 (2012).
ChIP
.
PubMed: 22275877
Tennant BR et al.The transcription factor Myt3 acts as a pro-survival factor in ß-cells.PLoS One 7:e51501 (2012).
ChIP
.
PubMed: 23236509
Gaertner B et al.Poised RNA polymerase II changes over developmental time and prepares genes for future expression.Cell Rep 2:1670-83 (2012).
ChIP
.
PubMed: 23260668
Whitworth DJ et al.Generation and Characterization of LIF-dependent Canine Induced Pluripotent Stem Cells from Adult Dermal Fibroblasts.Stem Cells Dev : (2012).
PubMed: 22221227
Stone JL et al.DNA double-strand breaks relieve USF-mediated repression of Dß2 germline transcription in developing thymocytes.J Immunol 188:2266-75 (2012).
PubMed: 22287717
Wu MF et al.SWI2/SNF2 chromatin remodeling ATPases overcome polycomb repression and control floral organ identity with the LEAFY and SEPALLATA3 transcription factors.Proc Natl Acad Sci U S A 109:3576-81 (2012).
ChIP
.
PubMed: 22323601
di Pietro M et al.Evidence for a functional role of epigenetically regulated midcluster HOXB genes in the development of Barrett esophagus.Proc Natl Acad Sci U S A 109:9077-82 (2012).
ChIP
.
PubMed: 22603795
Canovas S et al.Jumonji domain-containing protein 3 regulates histone 3 lysine 27 methylation during bovine preimplantation development.Proc Natl Acad Sci U S A 109:2400-5 (2012).
IHC (PFA fixed)
.
PubMed: 22308433
Herranz N et al.Lysyl oxidase-like 2 deaminates lysine 4 in histone H3.Mol Cell 46:369-76 (2012).
ChIP
;
Mouse, Human
.
PubMed: 22483618
Mysliwiec MR et al.Jarid2 (Jumonji, AT Rich Interactive Domain 2) Regulates NOTCH1 Expression via Histone Modification in the Developing Heart.J Biol Chem 287:1235-41 (2012).
ChIP
;
Mouse
.
PubMed: 22110129
Liu YJ et al.Essential Role of DPPA3 for Chromatin Condensation in Mouse Oocytogenesis.Biol Reprod 86:40 (2012).
PubMed: 22034526
Sher N et al.Developmental control of gene copy number by repression of replication initiation and fork progression.Genome Res 22:64-75 (2012).
PubMed: 22090375
Meldi KM et al.DNA methylation and histone modifications are associated with repression of the inhibin a promoter in the rat corpus luteum.Endocrinology 153:4905-17 (2012).
PubMed: 22865368
Lehmann L et al.Polycomb repressive complex 1 (PRC1) disassembles RNA polymerase II preinitiation complexes.J Biol Chem 287:35784-94 (2012).
PubMed: 22910904
Reamon-Buettner SM & Borlak J Dissecting epigenetic silencing complexity in the mouse lung cancer suppressor gene cadm1.PLoS One 7:e38531 (2012).
PubMed: 22701659
Katsushima K et al.Contribution of MicroRNA-1275 to Claudin11 Protein Suppression via a Polycomb-mediated Silencing Mechanism in Human Glioma Stem-like Cells.J Biol Chem 287:27396-406 (2012).
PubMed: 22736761
Pellakuru LG et al.Global levels of H3K27me3 track with differentiation in vivo and are deregulated by MYC in prostate cancer.Am J Pathol 181:560-9 (2012).
IHC
.
PubMed: 22713676
Abdel-Wahab O et al.ASXL1 mutations promote myeloid transformation through loss of PRC2-mediated gene repression.Cancer Cell 22:180-93 (2012).
PubMed: 22897849
Lai CB & Mager DL Role of Runt-related Transcription Factor 3 (RUNX3) in Transcription Regulation of Natural Cytotoxicity Receptor 1 (NCR1/NKp46), an Activating Natural Killer (NK) Cell Receptor.J Biol Chem 287:7324-34 (2012).
ChIP
.
PubMed: 22253448
Soto-Reyes E et al.Disruption of CTCF at the miR-125b1 locus in gynecological cancers.BMC Cancer 12:40 (2012).
ChIP
.
PubMed: 22277129
Zachariah RM et al.Novel MeCP2 isoform-specific antibody reveals the endogenous MeCP2E1 expression in murine brain, primary neurons and astrocytes.PLoS One 7:e49763 (2012).
PubMed: 23185431
Follmer NE et al.A polycomb group protein is retained at specific sites on chromatin in mitosis.PLoS Genet 8:e1003135 (2012).
PubMed: 23284300
Yu J et al.Microplate-based platform for combined chromatin and DNA methylation immunoprecipitation assays.BMC Mol Biol 12:49 (2011).
PubMed: 22098709
Schwartzman J et al.A DNA methylation microarray-based study identifies ERG as a gene commonly methylated in prostate cancer.Epigenetics 6:1248-56 (2011).
PubMed: 21946329
Testoni B et al.p53-paralog DNp73 oncogene is repressed by IFNa/STAT2 through the recruitment of the Ezh2 polycomb group transcriptional repressor.Oncogene 30:2670-8 (2011).
ChIP
.
PubMed: 21399658
Prigione A et al.Mitochondrial-Associated Cell Death Mechanisms Are Reset to an Embryonic-Like State in Aged Donor-Derived iPS Cells Harboring Chromosomal Aberrations.PLoS One 6:e27352 (2011).
ICC
.
PubMed: 22110631
Bending D et al.Epigenetic changes at Il12rb2 and Tbx21 in relation to plasticity behavior of Th17 cells.J Immunol 186:3373-82 (2011).
PubMed: 21307296
Cheng Z et al.Establishment of induced pluripotent stem cells from aged mice using bone marrow-derived myeloid cells.J Mol Cell Biol 3:91-8 (2011).
ChIP
.
PubMed: 21228011
McLaughlin CR & Chadwick BP Characterization of DXZ4 conservation in primates implies important functional roles for CTCF binding, array expression and tandem repeat organization on the X chromosome.Genome Biol 12:R37 (2011).
ICC/IF
;
Rhesus monkey
.
PubMed: 21489251
Yap DB et al.Somatic mutations at EZH2 Y641 act dominantly through a mechanism of selectively altered PRC2 catalytic activity, to increase H3K27 trimethylation.Blood 117:2451-9 (2011).
PubMed: 21190999
Chuang YS et al.Promyelocytic leukemia protein in retinoic Acid-induced chromatin remodeling of oct4 gene promoter.Stem Cells 29:660-9 (2011).
ChIP
;
Mouse
.
PubMed: 21360626
Xie L et al.KDM5B regulates embryonic stem cell self-renewal and represses cryptic intragenic transcription.EMBO J 30:1473-84 (2011).
WB
;
Mouse
.
PubMed: 21448134
Amat R & Gudas LJ RAR? is required for correct deposition and removal of Suz12 and H2A.Z in embryonic stem cells.J Cell Physiol 226:293-8 (2011).
PubMed: 20857416
Chan KM et al.Diverse factors are involved in maintaining X chromosome inactivation.Proc Natl Acad Sci U S A 108:16699-704 (2011).
ICC/IF
.
PubMed: 21940502
López A et al.The RNA silencing enzyme RNA polymerase v is required for plant immunity.PLoS Genet 7:e1002434 (2011).
ChIP
.
PubMed: 22242006
Kim DH et al.Requirement for MLL3 in p53 regulation of hepatic expression of small heterodimer partner and bile acid homeostasis.Mol Endocrinol 25:2076-83 (2011).
PubMed: 22034226
Splinter E et al.The inactive X chromosome adopts a unique three-dimensional conformation that is dependent on Xist RNA.Genes Dev 25:1371-83 (2011).
PubMed: 21690198
Wakabayashi Y et al.Histone 3 Lysine 9 (H3K9) Methyltransferase Recruitment to the Interleukin-2 (IL-2) Promoter Is a Mechanism of Suppression of IL-2 Transcription by the Transforming Growth Factor-{beta}-Smad Pathway.J Biol Chem 286:35456-65 (2011).
PubMed: 21862595
Testoni B et al.Chromatin dynamics of gene activation and repression in response to interferon alpha (IFN(alpha)) reveal new roles for phosphorylated and unphosphorylated forms of the transcription factor STAT2.J Biol Chem 286:20217-27 (2011).
PubMed: 21498520
Rouleau M et al.A key role for poly(ADP-ribose) polymerase 3 in ectodermal specification and neural crest development.PLoS One 6:e15834 (2011).
PubMed: 21264220
Spicuglia S et al.Characterisation of genome-wide PLZF/RARA target genes.PLoS One 6:e24176 (2011).
ChIP
.
PubMed: 21949697
Qüesta JI et al.Mutator transposon activation after UV-B involves chromatin remodeling.Epigenetics 5:352-63 (2010).
ChIP
.
PubMed: 20421734
Wood MD et al.Autonomous silencing of the imprinted Cdkn1c gene in stem cells.Epigenetics 5:214-21 (2010).
PubMed: 20372090
Kim DH et al.Vernalization-mediated VIN3 Induction Overcomes the LIKE-HETEROCHROMATIN PROTEIN1/POLYCOMB REPRESSION COMPLEX2-mediated epigenetic repression.Plant Physiol 154:949-57 (2010).
PubMed: 20671111
Ciavatta DJ et al.Epigenetic basis for aberrant upregulation of autoantigen genes in humans with ANCA vasculitis.J Clin Invest 120:3209-19 (2010).
PubMed: 20714105
Wang D et al.Distinct and histone-specific modifications mediate positive versus negative transcriptional regulation of TSHalpha promoter.PLoS One 5:e9853 (2010).
PubMed: 20352046
Li G et al.Jarid2 and PRC2, partners in regulating gene expression.Genes Dev 24:368-80 (2010).
PubMed: 20123894
Weishaupt H & Attema JL A Method to Study the Epigenetic Chromatin States of Rare Hematopoietic Stem and Progenitor Cells; MiniChIP-Chip.Biol Proced Online 12:1-17 (2010).
ChIP
;
Mouse
.
PubMed: 21406121
Kashyap V & Gudas LJ Epigenetic regulatory mechanisms distinguish retinoic acid-mediated transcriptional responses in stem cells and fibroblasts.J Biol Chem 285:14534-48 (2010).
PubMed: 20231276
Ke XS et al.Global profiling of histone and DNA methylation reveals epigenetic-based regulation of gene expression during epithelial to mesenchymal transition in prostate cells.BMC Genomics 11:669 (2010).
ChIP
.
PubMed: 21108828
Kumari D & Usdin K The distribution of repressive histone modifications on silenced FMR1 alleles provides clues to the mechanism of gene silencing in fragile X syndrome.Hum Mol Genet 19:4634-42 (2010).
ChIP
.
PubMed: 20843831
Eskeland R et al.Histone acetylation and the maintenance of chromatin compaction by Polycomb repressive complexes.Cold Spring Harb Symp Quant Biol 75:71-8 (2010).
ChIP
.
PubMed: 21502416
Lee H et al.Drosophila RB proteins repress differentiation-specific genes via two different mechanisms.Mol Cell Biol 30:2563-77 (2010).
ChIP
;
Drosophila melanogaster
.
PubMed: 20176807
de Bruijn DR et al.Severe Progressive Autism Associated with Two de novo Changes: A 2.6-Mb 2q31.1 Deletion and a Balanced t(14;21)(q21.1;p11.2) Translocation with Long-Range Epigenetic Silencing of LRFN5 Expression.Mol Syndromol 1:46-57 (2010).
ChIP
;
Human
.
PubMed: 20648246
Seenundun S et al.UTX mediates demethylation of H3K27me3 at muscle-specific genes during myogenesis.EMBO J 29:1401-11 (2010).
ChIP
;
Mouse
.
PubMed: 20300060
Gupta RA et al.Long non-coding RNA HOTAIR reprograms chromatin state to promote cancer metastasis.Nature 464:1071-6 (2010).
ChIP/Chip
;
Human
.
PubMed: 20393566
Kang X et al.SUMO-specific protease 2 is essential for suppression of polycomb group protein-mediated gene silencing during embryonic development.Mol Cell 38:191-201 (2010).
ChIP
;
Mouse
.
PubMed: 20417598
Stadtfeld M et al.Aberrant silencing of imprinted genes on chromosome 12qF1 in mouse induced pluripotent stem cells.Nature 465:175-81 (2010).
ChIP
;
Mouse
.
PubMed: 20418860
Lengner CJ et al.Derivation of pre-X inactivation human embryonic stem cells under physiological oxygen concentrations.Cell 141:872-83 (2010).
ChIP
;
Human
.
PubMed: 20471072
Kanhere A et al.Short RNAs are transcribed from repressed polycomb target genes and interact with polycomb repressive complex-2.Mol Cell 38:675-88 (2010).
PubMed: 20542000
Taube JH et al.Foxa1 functions as a pioneer transcription factor at transposable elements to activate Afp during differentiation of embryonic stem cells.J Biol Chem 285:16135-44 (2010).
ChIP
;
Mouse
.
PubMed: 20348100
Gerlitz G & Bustin M Efficient cell migration requires global chromatin condensation.J Cell Sci 123:2207-17 (2010).
ICC/IF
;
Mouse
.
PubMed: 20530575
Liber D et al.Epigenetic Priming of a Pre-B Cell-Specific Enhancer through Binding of Sox2 and Foxd3 at the ESC Stage.Cell Stem Cell 7:114-126 (2010).
ChIP
;
Mouse
.
PubMed: 20621055
Guenther MG et al.Chromatin structure and gene expression programs of human embryonic and induced pluripotent stem cells.Cell Stem Cell 7:249-57 (2010).
ChIP
;
Human
.
PubMed: 20682450
Palma K et al.Autoimmunity in Arabidopsis acd11 is mediated by epigenetic regulation of an immune receptor.PLoS Pathog 6: (2010).
ChIP
;
Arabidopsis thaliana
.
PubMed: 20949080
Riddle NC et al.Plasticity in patterns of histone modifications and chromosomal proteins in Drosophila heterochromatin.Genome Res : (2010).
ChIP
;
Drosophila melanogaster
.
PubMed: 21177972
Verdeguer F et al.A mitotic transcriptional switch in polycystic kidney disease.Nat Med 16:106-10 (2010).
ChIP
;
Mouse
.
PubMed: 19966811
Obier N & Müller AM Chromatin flow cytometry identifies changes in epigenetic cell states.Cells Tissues Organs 191:167-74 (2010).
Flow Cyt
;
Mouse
.
PubMed: 19776550
Seong IS et al.Huntingtin facilitates polycomb repressive complex 2.Hum Mol Genet 19:573-83 (2010).
ChIP
;
Mouse
.
PubMed: 19933700
Lu TY et al.Epithelial cell adhesion molecule regulation is associated with the maintenance of the undifferentiated phenotype of human embryonic stem cells.J Biol Chem 285:8719-32 (2010).
ChIP
;
Human
.
PubMed: 20064925
Gallagher PG et al.Mutation of a barrier insulator in the human ankyrin-1 gene is associated with hereditary spherocytosis.J Clin Invest 120:4453-65 (2010).
ChIP
.
PubMed: 21099109
Walter K et al.Aberrant expression of CD19 in AML with t(8;21) involves a poised chromatin structure and PAX5.Oncogene 29:2927-37 (2010).
PubMed: 20208555
Yokoyama NN et al.A role for YY1 in repression of dominant negative LEF-1 expression in colon cancer.Nucleic Acids Res 38:6375-88 (2010).
ChIP
.
PubMed: 20525792
Tanimoto K et al.Genome-wide identification and annotation of HIF-1a binding sites in two cell lines using massively parallel sequencing.Hugo J 4:35-48 (2010).
PubMed: 22132063
Ross PJ et al.Activation of bovine somatic cell nuclear transfer embryos by PLCZ cRNA injection.Reproduction 137:427-37 (2009).
PubMed: 19074500
Aranda P et al.Epigenetic signatures associated with different levels of differentiation potential in human stem cells.PLoS One 4:e7809 (2009).
ChIP
.
PubMed: 19915669
Araki Y et al.Genome-wide analysis of histone methylation reveals chromatin state-based regulation of gene transcription and function of memory CD8+ T cells.Immunity 30:912-25 (2009).
PubMed: 19523850
Ross PJ et al.Host cell detection of noncoding stuffer DNA contained in helper-dependent adenovirus vectors leads to epigenetic repression of transgene expression.J Virol 83:8409-17 (2009).
ChIP
;
Human
.
PubMed: 19515759
Eguizabal C et al.Generation of primordial germ cells from pluripotent stem cells.Differentiation 78:116-23 (2009).
ICC/IF
;
Mouse
.
PubMed: 19683852
Bartkuhn M et al.Active promoters and insulators are marked by the centrosomal protein 190.EMBO J 28:877-88 (2009).
ChIP
;
Human
.
PubMed: 19229299
Yu Z et al.The epidermal differentiation-associated Grainyhead gene Get1/Grhl3 also regulates urothelial differentiation.EMBO J 28:1890-903 (2009).
ChIP
;
Human
.
PubMed: 19494835
Chaturvedi CP et al.Dual role for the methyltransferase G9a in the maintenance of beta-globin gene transcription in adult erythroid cells.Proc Natl Acad Sci U S A 106:18303-8 (2009).
WB
;
Mouse
.
PubMed: 19822740
Yue R et al.Beta-arrestin1 regulates zebrafish hematopoiesis through binding to YY1 and relieving polycomb group repression.Cell 139:535-46 (2009).
ChIP
;
Zebrafish
.
PubMed: 19879840
Cervera AM et al.Inhibition of succinate dehydrogenase dysregulates histone modification in mammalian cells.Mol Cancer 8:89 (2009).
ICC/IF, IHC-P
;
Human
.
PubMed: 19849834
Mueller D et al.Misguided transcriptional elongation causes mixed lineage leukemia.PLoS Biol 7:e1000249 (2009).
ChIP
;
Mouse
.
PubMed: 19956800
Goto Y & Kimura H Inactive X chromosome-specific histone H3 modifications and CpG hypomethylation flank a chromatin boundary between an X-inactivated and an escape gene.Nucleic Acids Res 37:7416-28 (2009).
ChIP
.
PubMed: 19843608
Wu S et al.Loss of YY1 impacts the heterochromatic state and meiotic double-strand breaks during mouse spermatogenesis.Mol Cell Biol 29:6245-56 (2009).
ICC/IF
;
Mouse
.
PubMed: 19786570
Li Y et al.The target of the NSD family of histone lysine methyltransferases depends on the nature of the substrate.J Biol Chem 284:34283-95 (2009).
PubMed: 19808676
Margueron R et al.Role of the polycomb protein EED in the propagation of repressive histone marks.Nature 461:762-7 (2009).
ChIP
;
Drosophila melanogaster
.
PubMed: 19767730
Palmer MB et al.Yin yang 1 regulates the expression of snail through a distal enhancer.Mol Cancer Res 7:221-9 (2009).
PubMed: 19208738
Ke XS et al.Genome-wide profiling of histone h3 lysine 4 and lysine 27 trimethylation reveals an epigenetic signature in prostate carcinogenesis.PLoS One 4:e4687 (2009).
ChIP
.
PubMed: 19262738
Lee JH et al.Chromatin analysis of occluded genes.Hum Mol Genet 18:2567-74 (2009).
ChIP
.
PubMed: 19380460
Umezawa R et al.Aberrant histone modifications at the thyrotropin-releasing hormone gene in resistance to thyroid hormone: analysis of F455S mutant thyroid hormone receptor.Endocrinology 150:3425-32 (2009).
ChIP
.
PubMed: 19299458
Han Y et al.Orientation-dependent regulation of integrated HIV-1 expression by host gene transcriptional readthrough.Cell Host Microbe 4:134-46 (2008).
ChIP
.
PubMed: 18692773
Stielow B et al.SUMO-modified Sp3 represses transcription by provoking local heterochromatic gene silencing.EMBO Rep 9:899-906 (2008).
PubMed: 18617891
Ross PJ et al.Polycomb gene expression and histone H3 lysine 27 trimethylation changes during bovine preimplantation development.Reproduction 136:777-85 (2008).
PubMed: 18784248
Margueron R et al.Ezh1 and Ezh2 maintain repressive chromatin through different mechanisms.Mol Cell 32:503-18 (2008).
PubMed: 19026781
Sanz LA et al.A mono-allelic bivalent chromatin domain controls tissue-specific imprinting at Grb10.EMBO J 27:2523-32 (2008).
PubMed: 18650936
Blewitt ME et al.SmcHD1, containing a structural-maintenance-of-chromosomes hinge domain, has a critical role in X inactivation.Nat Genet 40:663-9 (2008).
ICC/IF
;
Mouse
.
PubMed: 18425126
Verona RI et al.The transcriptional status but not the imprinting control region determines allele-specific histone modifications at the imprinted H19 locus.Mol Cell Biol 28:71-82 (2008).
ChIP
;
Mouse
.
PubMed: 17967893
Nelson JD et al.Transcription of laminin gamma1 chain gene in rat mesangial cells: constitutive and inducible RNA polymerase II recruitment and chromatin states.Am J Physiol Renal Physiol 294:F525-33 (2008).
ChIP
;
Rat
.
PubMed: 18184742
Jeon BG et al.S-adenosylhomocysteine treatment of adult female fibroblasts alters X-chromosome inactivation and improves in vitro embryo development after somatic cell nuclear transfer.Reproduction 135:815-28 (2008).
PubMed: 18304987
Luco RF et al.Targeted deficiency of the transcriptional activator Hnf1alpha alters subnuclear positioning of its genomic targets.PLoS Genet 4:e1000079 (2008).
ICC/IF
;
Mouse
.
PubMed: 18497863
Casati P et al.Histone acetylation and chromatin remodeling are required for UV-B-dependent transcriptional activation of regulated genes in maize.Plant Cell 20:827-42 (2008).
ChIP
;
Plants
.
PubMed: 18398050
Vokes SA et al.A genome-scale analysis of the cis-regulatory circuitry underlying sonic hedgehog-mediated patterning of the mammalian limb.Genes Dev 22:2651-63 (2008).
ChIP
;
Mouse
.
PubMed: 18832070
Gal-Yam EN et al.Frequent switching of Polycomb repressive marks and DNA hypermethylation in the PC3 prostate cancer cell line.Proc Natl Acad Sci U S A 105:12979-84 (2008).
ChIP
;
Human
.
PubMed: 18753622
Wei Y et al.Loss of trimethylation at lysine 27 of histone H3 is a predictor of poor outcome in breast, ovarian, and pancreatic cancers.Mol Carcinog 47:701-6 (2008).
PubMed: 18176935
Kim A et al.Distinctive signatures of histone methylation in transcribed coding and noncoding human beta-globin sequences.Mol Cell Biol 27:1271-9 (2007).
PubMed: 17158930
de la Cruz CC et al.The polycomb group protein SUZ12 regulates histone H3 lysine 9 methylation and HP1 alpha distribution.Chromosome Res 15:299-314 (2007).
PubMed: 17406994
Chadwick BP Variation in Xi chromatin organization and correlation of the H3K27me3 chromatin territories to transcribed sequences by microarray analysis.Chromosoma 116:147-57 (2007).
PubMed: 17103221
Rathke C et al.Transition from a nucleosome-based to a protamine-based chromatin configuration during spermiogenesis in Drosophila.J Cell Sci 120:1689-700 (2007).
PubMed: 17452629
Tesar PJ et al.New cell lines from mouse epiblast share defining features with human embryonic stem cells.Nature 448:196-9 (2007).
PubMed: 17597760
Baroux C et al.The triploid endosperm genome of Arabidopsis adopts a peculiar, parental-dosage-dependent chromatin organization.Plant Cell 19:1782-94 (2007).
PubMed: 17557811
Skalníková M et al.Distinct patterns of histone methylation and acetylation in human interphase nuclei.Physiol Res : (2007).
PubMed: 17298208
Tanaka T et al.hCAS/CSE1L associates with chromatin and regulates expression of select p53 target genes.Cell 130:638-50 (2007).
ChIP
;
Human
.
PubMed: 17719542
Blais A et al.Retinoblastoma tumor suppressor protein-dependent methylation of histone H3 lysine 27 is associated with irreversible cell cycle exit.J Cell Biol 179:1399-412 (2007).
ChIP
;
Mouse
.
PubMed: 18166651
Donati G et al.Dynamic recruitment of transcription factors and epigenetic changes on the ER stress response gene promoters.Nucleic Acids Res 34:3116-27 (2006).
IP
;
Human
.
PubMed: 16757577
Kanduri C et al.The length of the transcript encoded from the Kcnq1ot1 antisense promoter determines the degree of silencing.EMBO J 25:2096-106 (2006).
PubMed: 16628224
Lee TI et al.Control of developmental regulators by polycomb in human embryonic stem cells.Cell 125:301-13 (2006).
PubMed: 16630818
Nelson JD et al.Protocol for the fast chromatin immunoprecipitation (ChIP) method.Nat Protoc 1:179-85 (2006).
PubMed: 17406230
Kahn TG et al.Polycomb complexes and the propagation of the methylation mark at the Drosophila ubx gene.J Biol Chem 281:29064-75 (2006).
PubMed: 16887811
Greaves IK et al.The X and Y chromosomes assemble into H2A.Z-containing [corrected] facultative heterochromatin [corrected] following meiosis.Mol Cell Biol 26:5394-405 (2006).
PubMed: 16809775
Shi J & Dawe RK Partitioning of the maize epigenome by the number of methyl groups on histone H3 lysines 9 and 27.Genetics 173:1571-83 (2006).
IF
;
Zea mays
.
PubMed: 16624902
West KL et al.A direct interaction between the RAG2 C terminus and the core histones is required for efficient V(D)J recombination.Immunity 23:203-12 (2005).
PubMed: 16111638
Baarends WM et al.Silencing of unpaired chromatin and histone H2A ubiquitination in mammalian meiosis.Mol Cell Biol 25:1041-53 (2005).
PubMed: 15657431
Tang M et al.Decidual differentiation of stromal cells promotes Proprotein Convertase 5/6 expression and lefty processing.Endocrinology 146:5313-20 (2005).
PubMed: 16141390
Chen H et al.Down-regulation of human DAB2IP gene expression mediated by polycomb Ezh2 complex and histone deacetylase in prostate cancer.J Biol Chem 280:22437-44 (2005).
PubMed: 15817459
Guenther MG et al.Global and Hox-specific roles for the MLL1 methyltransferase.Proc Natl Acad Sci U S A 102:8603-8 (2005).
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