Histone H3 (phospho S10) Assay Kit (In Situ) (ab115126)

製品の概要

  • 製品名Histone H3 (phospho S10) Assay Kit (In Situ)
    Histone H3 (S10 Phosphorylation) キット 製品一覧
  • テスト
    1 x 96 test
  • サンプルの種類
    Adherent cells
  • アッセイタイプCell-based (quantitative)
  • 全工程の試験時間
    3h 00m
  • 種交差性

    交差が予測される動物種: all Mammals
  • 製品の概要

    Phosphorylation of histone H3 at serine 10 is conserved through eukaryotes, and an increase in phosphorylation has been shown to correlate with gene activation and cell growth. Histone H3 (phospho S10) is regulated by the cell cycle and has been used as a mitotic marker. Detection in the change of histone H3 (phospho S10) associated with the cell cycle, apoptosis, inhibitor or activator treatment would provide useful information for better understanding the pathological process of some diseases.

    Abcam's Histone H3 (phospho S10) Assay Kit (In Situ) (ab115126) allows the user to measure histone H3 (phospho S10) in situ using cultured adherent cells in a quick and efficient procedure which can be finished within 3 hours.

  • アプリケーション適用あり: Functional Studiesmore details

法規制情報

製品の特性

    アプリケーション

    Our Abpromise guarantee covers the use of ab115126 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    アプリケーション Abreviews 特記事項
    Functional Studies Use at an assay dependent concentration.

    Histone H3 (phospho S10) Assay Kit (In Situ) 画像

    • Log-phase MCF-7 cells were serum-starved overnight, and serum was added back for 30 minutes followed by treatment with Calyculin A (CL-A, 0.2 µM for 30 minutes). The level of H3 phosphorylation at ser10 was measured with ab115126.

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    Histone H3 (phospho S10) Assay Kit (In Situ) (ab115126) 使用論文

    ab115126 has not yet been referenced specifically in any publications.

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