Histone H3 (pan-methyl K79) Quantification Kit (Fluorometric) (ab115090)

製品の概要

  • 製品名Histone H3 (pan-methyl K79) Quantification Kit (Fluorometric)
    Histone H3 (K79 methylation) キット 製品一覧
  • テスト
    1 x 96 test
  • 検出感度
    0.4 ng/well
  • 検出範囲
    5 ng/well - 2000 ng/well
  • 全工程の試験時間
    2h 30m
  • 種交差性
    交差種: Mouse, Human
    交差が予測される動物種: all Mammals
  • 製品の概要

    Methylation of histone H3 at lysine 79 is catalyzed by Dot1 in mammalian cells. Intergenic H3 (mono-methyl K79) is a mark of enhancer regions and may provide unique binding surfaces along the chromatin fibre to stabilize interactions between enhancers and their target promoters. H3 (di-methyl K79) and H3 (tri-methyl K79) are also widespread histone modifications and are associated with transcriptionally active genes. Increased global H3 (methyl K79) is also found to be involved in some pathological processes such as leukemogenesis in humans.

    Histone H3 (pan-methyl K79) Quantification Kit (Fluorometric) (ab115090) allows the user to specifically measure global mono-, di-, and tri-methylation of histone H3K79 fluorometrically using a variety of mammalian cells including fresh and frozen tissues, cultured adherent and suspension cells.

  • アプリケーション適用あり: Functional Studiesmore details

製品の特性

    アプリケーション

    Our Abpromise guarantee covers the use of ab115090 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    アプリケーション Abreviews 特記事項
    Functional Studies Use at an assay dependent concentration.

    プロトコール

    Histone H3 (pan-methyl K79) Quantification Kit (Fluorometric) (ab115090) 使用論文

    ab115090 has not yet been referenced specifically in any publications.

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