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PubMed: 29343685
Gao Y & Ge W The histone methyltransferase DOT1L inhibits osteoclastogenesis and protects against osteoporosis.Cell Death Dis 9:33 (2018).
PubMed: 29348610
Getun IV et al.Functional Roles of Acetylated Histone Marks at Mouse Meiotic Recombination Hot Spots.Mol Cell Biol 37:N/A (2017).
PubMed: 27821479
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PubMed: 28031330
Cavero S et al.Impact of histone H4K16 acetylation on the meiotic recombination checkpoint in Saccharomyces cerevisiae.Microb Cell 3:606-620 (2016).
WB
;
Saccharomyces cerevisiae
.
PubMed: 28357333
Reynoird N et al.Coordination of stress signals by the lysine methyltransferase SMYD2 promotes pancreatic cancer.Genes Dev 30:772-85 (2016).
PubMed: 26988419
Lu S et al.The transcription factor c-Fos coordinates with histone lysine-specific demethylase 2A to activate the expression of cyclooxygenase-2.Oncotarget 6:34704-17 (2015).
WB
.
PubMed: 26430963
Woo Park J et al.RE-IIBP Methylates H3K79 and Induces MEIS1-mediated Apoptosis via H2BK120 Ubiquitination by RNF20.Sci Rep 5:12485 (2015).
WB
.
PubMed: 26206755
Yao X et al.The Mediator subunit MED23 couples H2B mono-ubiquitination to transcriptional control and cell fate determination.EMBO J 34:2885-902 (2015).
WB
.
PubMed: 26330467
Li D et al.Epigenetic regulation of traf2- and Nck-interacting kinase (TNIK) in polycystic ovary syndrome.Am J Transl Res 7:1152-60 (2015).
ChIP
.
PubMed: 26279758
Deshpande AJ et al.AF10 regulates progressive H3K79 methylation and HOX gene expression in diverse AML subtypes.Cancer Cell 26:896-908 (2014).
PubMed: 25464900
Rossodivita AA et al.Histone H3 K79 methylation states play distinct roles in UV-induced sister chromatid exchange and cell cycle checkpoint arrest in Saccharomyces cerevisiae.Nucleic Acids Res 42:6286-99 (2014).
WB
;
Saccharomyces cerevisiae
.
PubMed: 24748660
Rossmann MP & Stillman B Immunoblotting histones from yeast whole-cell protein extracts.Cold Spring Harb Protoc 2013:625-30 (2013).
PubMed: 23818662
Oksenych V et al.Histone methyltransferase DOT1L drives recovery of gene expression after a genotoxic attack.PLoS Genet 9:e1003611 (2013).
PubMed: 23861670
Ontoso D et al.Dynamics of DOT1L localization and H3K79 methylation during meiotic prophase I in mouse spermatocytes.Chromosoma : (2013).
IF
.
PubMed: 24105599
Sadhu MJ et al.Nutritional control of epigenetic processes in yeast and human cells.Genetics 195:831-44 (2013).
PubMed: 23979574
Youn MY et al.JMJD5, a Jumonji C (JmjC) Domain-containing Protein, Negatively Regulates Osteoclastogenesis by Facilitating NFATc1 Protein Degradation.J Biol Chem 287:12994-3004 (2012).
WB
;
Human
.
PubMed: 22375008
Bjørnstad LG et al.Human ALKBH4 interacts with proteins associated with transcription.PLoS One 7:e49045 (2012).
WB
.
PubMed: 23145062
Osborne EA et al.Symmetry, asymmetry, and kinetics of silencing establishment in Saccharomyces cerevisiae revealed by single-cell optical assays.Proc Natl Acad Sci U S A 108:1209-16 (2011).
WB
;
Saccharomyces cerevisiae
.
PubMed: 21262833
FitzGerald J et al.Regulation of the DNA damage response and gene expression by the Dot1L histone methyltransferase and the 53Bp1 tumour suppressor.PLoS One 6:e14714 (2011).
WB
.
PubMed: 21383990
Milcarek C et al.The Eleven-Nineteen Lysine-rich Leukemia Gene (ELL2) Influences the Histone H3 Protein Modifications Accompanying the Shift to Secretory Immunoglobulin Heavy Chain mRNA Production.J Biol Chem 286:33795-803 (2011).
ChIP
;
Mouse
.
PubMed: 21832080
Vernimmen D et al.Polycomb eviction as a new distant enhancer function.Genes Dev 25:1583-8 (2011).
ChIP
;
Mouse
.
PubMed: 21828268
Tran BN et al.Novel Histone H3 Binding Protein ORF158L from the Singapore Grouper Iridovirus.J Virol 85:9159-66 (2011).
WB
.
PubMed: 21715494
Cook AJ et al.A specific function for the histone chaperone NASP to fine-tune a reservoir of soluble H3-H4 in the histone supply chain.Mol Cell 44:918-27 (2011).
PubMed: 22195965
Chang MJ et al.Histone H3 lysine 79 methyltransferase Dot1 is required for immortalization by MLL oncogenes.Cancer Res 70:10234-42 (2010).
PubMed: 21159644
Feng Y et al.Early mammalian erythropoiesis requires the Dot1L methyltransferase.Blood 116:4483-91 (2010).
PubMed: 20798234
Zhu Z et al.PHF8 is a histone H3K9me2 demethylase regulating rRNA synthesis.Cell Res 20:794-801 (2010).
ChIP
.
PubMed: 20531378
Lin H et al.Coordinated regulation of active and repressive histone methylations by a dual-specificity histone demethylase ceKDM7A from Caenorhabditis elegans.Cell Res 20:899-907 (2010).
PubMed: 20567262
Horáková AH et al.SUV39h-independent association of HP1 beta with fibrillarin-positive nucleolar regions.Chromosoma 119:227-41 (2010).
WB, ChIP
;
Mouse
.
PubMed: 20033197
Singh P et al.Allele-specific H3K79 Di- versus trimethylation distinguishes opposite parental alleles at imprinted regions.Mol Cell Biol 30:2693-707 (2010).
ChIP
;
Mouse
.
PubMed: 20351169
Conde F et al.The Dot1 histone methyltransferase and the Rad9 checkpoint adaptor contribute to cohesin-dependent double-strand break repair by sister chromatid recombination in Saccharomyces cerevisiae.Genetics 182:437-46 (2009).
PubMed: 19332880
Jacob Y et al.ATXR5 and ATXR6 are H3K27 monomethyltransferases required for chromatin structure and gene silencing.Nat Struct Mol Biol 16:763-8 (2009).
PubMed: 19503079
Jones B et al.The histone H3K79 methyltransferase Dot1L is essential for mammalian development and heterochromatin structure.PLoS Genet 4:e1000190 (2008).
WB, ICC/IF
.
PubMed: 18787701
Frederiks F et al.Nonprocessive methylation by Dot1 leads to functional redundancy of histone H3K79 methylation states.Nat Struct Mol Biol 15:550-7 (2008).
WB
.
PubMed: 18511943
Steger DJ et al.DOT1L/KMT4 recruitment and H3K79 methylation are ubiquitously coupled with gene transcription in mammalian cells.Mol Cell Biol 28:2825-39 (2008).
ChIP
;
Mouse
.
PubMed: 18285465
Martinato F et al.Analysis of Myc-induced histone modifications on target chromatin.PLoS ONE 3:e3650 (2008).
ChIP
;
Human
.
PubMed: 18985155
Barski A et al.High-resolution profiling of histone methylations in the human genome.Cell 129:823-37 (2007).
PubMed: 17512414
Guccione E et al.Myc-binding-site recognition in the human genome is determined by chromatin context.Nat Cell Biol 8:764-70 (2006).
PubMed: 16767079
Shahbazian MD et al.Histone H2B ubiquitylation controls processive methylation but not monomethylation by Dot1 and Set1.Mol Cell 19:271-7 (2005).
PubMed: 16039595
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