Anti-Histone acetyltransferase MYST3 抗体 (ab110945)


  • 製品名Anti-Histone acetyltransferase MYST3 antibody
    Histone acetyltransferase MYST3 一次抗体 製品一覧
  • 製品の詳細
    Goat polyclonal to Histone acetyltransferase MYST3
  • アプリケーション適用あり: ELISA, IHC-Pmore details
    適用なし: WB
  • 種交差性
    交差種: Human
  • 免疫原

    Synthetic peptide:


    , corresponding to internal sequence amino acids 1361-1372 of Human KAT6A/ HAT3 (NP_006757.2).

  • ポジティブ・コントロール
    • Human Adrenal tissue.


  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term.
  • バッファーpH: 7.30
    Preservative: 0.02% Sodium azide
    Constituents: Tris buffered saline, 0.5% BSA
  • Concentration information loading...
  • 精製度Protein G purified
  • ポリ/モノポリクローナル
  • アイソタイプIgG
  • 研究分野


Our Abpromise guarantee covers the use of ab110945 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
ELISA 1/16000.
IHC-P Use a concentration of 3.75 µg/ml.
  • 追加情報Is unsuitable for WB.
  • ターゲット情報

    • 機能Histone acetyltransferase that acetylates lysine residues in histone H3 and histone H4 (in vitro). Component of the MOZ/MORF complex which has a histone H3 acetyltransferase activity. May act as a transcriptional coactivator for RUNX1 and RUNX2.
    • 関連疾患Note=Chromosomal aberrations involving MYST3 may be a cause of acute myeloid leukemias. Translocation t(8;16)(p11;p13) with CREBBP; translocation t(8;22)(p11;q13) with EP300. MYST3-CREBBP may induce leukemia by inhibiting RUNX1-mediated transcription. Inversion inv(8)(p11;q13) generates the MYST3-NCOA2 oncogene, which consists of the N-terminus part of MYST3/MOZ and the C-terminus part of NCOA2/TIF2. MYST3-NCOA2 binds to CREBBP and disrupts its function in transcription activation.
      Note=A chromosomal aberration involving MYST3 is a cause of therapy-related myelodysplastic syndrome. Translocation t(2;8)(p23;p11.2) with ASXL2 generates a MYST3-ASXL2 fusion protein.
    • 配列類似性Belongs to the MYST (SAS/MOZ) family.
      Contains 1 C2HC-type zinc finger.
      Contains 1 H15 (linker histone H1/H5 globular) domain.
      Contains 2 PHD-type zinc fingers.
    • ドメインThe N-terminus is involved in transcriptional activation while the C-terminus is involved in transcriptional repression.
    • 翻訳後修飾Autoacetylated.
      Phosphorylated upon DNA damage, probably by ATM or ATR.
    • 細胞内局在Nucleus. Partially concentrated in subnuclear foci distinct from PML bodies, and excluded from the nucleoli.
    • Information by UniProt
    • 参照データベース
    • 別名
      • HAT 3 antibody
      • Histone acetyltransferase MYST3 antibody
      • Monocytic leukemia zinc finger protein antibody
      • MOZ antibody
      • MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3 antibody
      • MYST histone acetyltransferase (monocytic leukemia) 3 antibody
      • MYST protein 3 antibody
      • MYST-3 antibody
      • MYST3 antibody
      • MYST3_HUMAN antibody
      • OTTHUMP00000197392 antibody
      • OTTHUMP00000197394 antibody
      • OTTHUMP00000225722 antibody
      • Runt related transcription factor binding protein 2 antibody
      • Runt-related transcription factor-binding protein 2 antibody
      • RUNXBP2 antibody
      • SAS2 antibody
      • SAS2 and TIP60 protein 3 antibody
      • TIP60 protein 3 antibody
      • YBF2/SAS3 antibody
      • ZC2HC6A antibody
      • Zinc finger protein 220 antibody
      • ZNF220 antibody
      see all

    Anti-Histone acetyltransferase MYST3 antibody 画像

    • ab110945, at 3.75µg/ml, staining KAT6A / HAT3 in formalin-fixed, paraffin-embedded Human Adrenal tissue by Immunohistochemistry.

    Anti-Histone acetyltransferase MYST3 antibody (ab110945) 使用論文

    ab110945 has not yet been referenced specifically in any publications.

    Product Wall

    There are currently no Abreviews or Questions for ab110945.
    Please use the links above to contact us or submit feedback about this product.