製品の概要

  • 製品名Anti-HIST1H2BJ antibody
  • 製品の詳細
    Rabbit polyclonal to HIST1H2BJ
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Synthetic peptide corresponding to Human HIST1H2BJ aa 60-90 (internal sequence) conjugated to Keyhole Limpet Haemocyanin (KLH).
    Database link: P06899

  • ポジティブ・コントロール
    • CEM cell line lysate

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Store at 4°C (up to 6 months). Store at -20°C long term.
  • バッファーPreservative: 0.09% Sodium Azide
    Constituents: PBS
  • Concentration information loading...
  • 精製度Immunogen affinity purified
  • 特記事項(精製)ab107806 is purified through a protein A column, followed by peptide affinity purification.
  • ポリ/モノポリクローナル
  • アイソタイプIgG
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab107806 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/100 - 1/500. Predicted molecular weight: 14 kDa.

ターゲット情報

  • 機能Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
    Has broad antibacterial activity. May contribute to the formation of the functional antimicrobial barrier of the colonic epithelium, and to the bactericidal activity of amniotic fluid.
  • 配列類似性Belongs to the histone H2B family.
  • 翻訳後修飾Monoubiquitination of Lys-121 by the RNF20/40 complex gives a specific tag for epigenetic transcriptional activation and is also prerequisite for histone H3 'Lys-4' and 'Lys-79' methylation. It also functions cooperatively with the FACT dimer to stimulate elongation by RNA polymerase II.
    Phosphorylated on Ser-15 by STK4/MST1 during apoptosis; which facilitates apoptotic chromatin condensation. Also phosphorylated on Ser-15 in response to DNA double strand breaks (DSBs), and in correlation with somatic hypermutation and immunoglobulin class-switch recombination.
  • 細胞内局在Nucleus. Chromosome.
  • Information by UniProt
  • 参照データベース
  • 別名
    • H2B histone family member R antibody
    • H2B/r antibody
    • H2B1J_HUMAN antibody
    • H2BFR antibody
    • HIST1H2BJ antibody
    • Histone 1 H2bj antibody
    • Histone cluster 1 H2bj antibody
    • Histone H2B type 1-J antibody
    • Histone H2B.1 antibody
    • Histone H2B.r antibody
    see all

Anti-HIST1H2BJ antibody 画像

  • Anti-HIST1H2BJ antibody (ab107806) at 1/100 dilution + CEM cell line lysate at 35 µg

    Predicted band size : 14 kDa

Anti-HIST1H2BJ antibody (ab107806) 使用論文

ab107806 has not yet been referenced specifically in any publications.

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There are currently no Abreviews or Questions for ab107806.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"