Anti-Hirudin 抗体 [2D7] (ab17198)

製品の概要

  • 製品名Anti-Hirudin antibody [2D7]
  • 製品の詳細
    Mouse monoclonal [2D7] to Hirudin
  • 特異性The affinity (Kd) of this antibody for rHV2K47 is 4.5x10E-7 M
  • アプリケーション適用あり: ELISA, WBmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Recombinant full length protein (Human).

  • エピトープThe epitope of this antibody is located at the C-terminal end of hirudin.

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • バッファーPreservative: 15mM Sodium Azide
    Constituents: 0.5M Sodium chloride, 0.01M PBS, pH 7.4
  • Concentration information loading...
  • 精製度Protein G purified
  • ポリ/モノモノクローナル
  • クローン名2D7
  • ミエローマx63-Ag8.653
  • アイソタイプIgG1
  • 軽鎖の種類kappa
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab17198 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
ELISA
WB
  • 追加情報ELISA: 1/2000.
    WB: Use at an assay dependent dilution. ab17198 reacts with hirudin in both reduced and unreduced forms. Detects a band of approximately 7 kDa.

    Not tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 関連性Hirudin is a highly effective and very specific anticoagulant which specifically inhibits formation of fibrin and activation of factors V, VIII and XIII by forming irreversible, noncovalent 1:1 complexes with a-thrombin. Hirudin is a 65 amino acid polypeptide, 7 kDa protein naturally originating from the medical leech Hirudo medicinalis. It is the most potent thrombin inhibitor known to date.
    • 細胞内局在Secreted
    • 別名
      • Hirudin 1 antibody
      • Lepirudin antibody
      • Refludan antibody

    Anti-Hirudin antibody [2D7] (ab17198) 使用論文

    ab17198 has not yet been referenced specifically in any publications.

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    Thank you for contacting Abcam.
    I have heard back from the lab and they have told me that ab17198reacts to the variant 2 form of Hirudin, not variant 1.
    I am sorry that I could not help you further in this matter, but if there is anything els...

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    Thank you for contacting us.

    We test ab17198 and ab36390 byaccessing their binding abilities to human thrombin and to complex of human thrombin with the thromobin inhibitor hirudin. We have not tested the antibodies in other species other th...

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"