製品の概要

  • 製品名
  • 製品の詳細
    Rabbit polyclonal to HIPK1
  • アプリケーション
    適用あり: WBmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Mouse, Rat, Rabbit, Horse, Guinea pig, Cow, Cat, Dog
  • 免疫原

    Synthetic peptide derived from a region within residues: LNLSQNQQSS AAPTSQERSS NPAPRRQQAF VAPLSQAPYT FQHGSPLHST, corresponding to internal amino acids 1044-1093 of Human HIPK1 (NP_938009).

  • ポジティブ・コントロール
    • 721_B cell lysate

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab90103 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 131 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

ターゲット情報

  • 機能
    May play a role as a corepressor for homeodomain transcription factors. Phosphorylates DAXX in response to stress, and mediates its translocation from the nucleus to the cytoplasm. May be involved in malignant squamous cell tumor formation.
  • 組織特異性
    Ubiquitously expressed with highest levels in skeletal muscle and heart. Overexpressed in breast cancer cell lines.
  • 配列類似性
    Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. HIPK subfamily.
    Contains 1 protein kinase domain.
  • 翻訳後修飾
    Autophosphorylated. Phosphorylated and activated by JNK1.
  • 細胞内局在
    Nucleus. Cytoplasm. Predominantly nuclear.
  • Information by UniProt
  • 参照データベース
  • 別名
    • Hipk 1 antibody
    • Hipk1 antibody
    • HIPK1_HUMAN antibody
    • Homeodomain interacting protein kinase 1 antibody
    • Homeodomain interacting protein kinase 1 like protein antibody
    • Homeodomain-interacting protein kinase 1 antibody
    • Myak antibody
    • Nbak 2 antibody
    • Nbak2 antibody
    • Nuclear body associated kinase 2 antibody
    • Nuclear body associated kinase 2b antibody
    see all

画像

  • Anti-HIPK1 antibody (ab90103) at 1 µg/ml (in 5% skim milk / PBS buffer) + 721_B cell lysate at 10 µg

    Secondary
    HRP conjugated anti-Rabbit IgG at 1/50000 dilution

    Predicted band size : 131 kDa

プロトコール

参考文献

ab90103 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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