製品の概要

  • 製品名Anti-HIPK1 antibody
    HIPK1 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal to HIPK1
  • アプリケーション適用あり: WB, IHC-Pmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Recombinant fragment, corresponding to amino acids 330-430 of Human HIPK1

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab58136 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB
IHC-P
  • 追加情報WB: Use at a concentration of 1-5 µg/ml.
    IHC-P: Use at a concentration of 3 µg/ml.

    This antibody has only been tested in WB against the recombinant fragment used as immunogen. We have no data on the detection of endogenous protein.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 機能May play a role as a corepressor for homeodomain transcription factors. Phosphorylates DAXX in response to stress, and mediates its translocation from the nucleus to the cytoplasm. May be involved in malignant squamous cell tumor formation.
    • 組織特異性Ubiquitously expressed with highest levels in skeletal muscle and heart. Overexpressed in breast cancer cell lines.
    • 配列類似性Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. HIPK subfamily.
      Contains 1 protein kinase domain.
    • 翻訳後修飾Autophosphorylated. Phosphorylated and activated by JNK1.
    • 細胞内局在Nucleus. Cytoplasm. Predominantly nuclear.
    • Information by UniProt
    • 参照データベース
    • 別名
      • Hipk 1 antibody
      • Hipk1 antibody
      • HIPK1_HUMAN antibody
      • Homeodomain interacting protein kinase 1 antibody
      • Homeodomain interacting protein kinase 1 like protein antibody
      • Homeodomain-interacting protein kinase 1 antibody
      • Myak antibody
      • Nbak 2 antibody
      • Nbak2 antibody
      • Nuclear body associated kinase 2 antibody
      • Nuclear body associated kinase 2b antibody
      see all

    Anti-HIPK1 antibody 画像

    • HIPK1 antibody (ab58136) used in immunohistochemistry at 3ug/ml on formalin fixed and paraffin embedded human salivary gland.
    • Western blot against tagged recombinant protein immunogen using ab58136 HIPK1 antibody at 1ug/ml. Predicted band size of immunogen is 34 kDa

    Anti-HIPK1 antibody (ab58136) 使用論文

    This product has been referenced in:
    • Park BW  et al. Homeodomain-interacting Protein Kinase 1 (HIPK1) Expression in Breast Cancer Tissues. Jpn J Clin Oncol 42:1138-45 (2012). IHC-P . Read more (PubMed: 23071292) »

    See 1 Publication for this product

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    There are currently no Abreviews or Questions for ab58136.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"