製品の概要

  • 製品名Anti-HIP1R antibody
    HIP1R 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to HIP1R
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Rat, Human
  • 免疫原

    Synthetic peptide:

    QDHQLDKKDGIYPAQLVNY

    , corresponding to N terminal amino acids 264-282 of Human HIP1R

  • ポジティブ・コントロール
    • P2 microsomal fraction from embryonic rat brain. Rat brain extract.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab79162 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/1000 - 1/2000. Detects a band of approximately 116 kDa (predicted molecular weight: 119 kDa).

ターゲット情報

  • 機能Component of clathrin-coated pits and vesicles, that may link the endocytic machinery to the actin cytoskeleton. Binds 3-phosphoinositides (via ENTH domain). May act through the ENTH domain to promote cell survival by stabilizing receptor tyrosine kinases following ligand-induced endocytosis.
  • 組織特異性Brain, heart, kidney, pancreas, and liver, but not in lung or placenta.
  • 配列類似性Belongs to the SLA2 family.
    Contains 1 ENTH (epsin N-terminal homology) domain.
    Contains 1 I/LWEQ domain.
  • ドメインBinds F-actin via the talin-like I/LWEQ domain.
  • 細胞内局在Cytoplasm > perinuclear region. Endomembrane system. Cytoplasmic vesicle > clathrin-coated vesicle membrane. Membrane-associated protein, mainly localized at the endocytic compartments and in the perinuclear region.
  • Information by UniProt
  • 参照データベース
  • 別名
    • FLJ14000 antibody
    • FLJ27022 antibody
    • HIP-12 antibody
    • Hip1 related antibody
    • HIP1-related protein antibody
    • HIP12 antibody
    • HIP1R antibody
    • HIP1R_HUMAN antibody
    • HIP3 antibody
    • Huntingtin Interacting Protein 1 Related antibody
    • Huntingtin interacting protein 12 antibody
    • Huntingtin-interacting protein 1-related protein antibody
    • Huntingtin-interacting protein 12 antibody
    • ILWEQ antibody
    • KIAA0655 antibody
    • MGC47513 antibody
    see all

Anti-HIP1R antibody 画像

Anti-HIP1R antibody (ab79162) 使用論文

ab79162 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"