製品の概要

  • 製品名Anti-HIC1 antibody
    HIC1 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to HIC1
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Synthetic peptide conjugated to KLH, corresponding to a region within C terminal amino acids 497-527 of Human HIC1 (NP_001091672.1, NP_006488.2)

  • ポジティブ・コントロール
    • NCI-H292 cell lysate

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab116557 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/100 - 1/500. Predicted molecular weight: 77 kDa.

ターゲット情報

  • 機能Transcriptional repressor. May act as a tumor suppressor. May be involved in development of head, face, limbs and ventral body wall.
  • 組織特異性Ubiquitously expressed with highest levels found in lung, colon, prostate, thymus, testis and ovary. Expression is absent or decreased in many tumor cells.
  • 配列類似性Belongs to the krueppel C2H2-type zinc-finger protein family. Hic subfamily.
    Contains 1 BTB (POZ) domain.
    Contains 5 C2H2-type zinc fingers.
  • 翻訳後修飾Acetylated on several residues, including Lys-333. Lys-333 is deacetylated by SIRT1.
    Sumoylated on Lys-333 by a PIAS family member, which positively regulates transcriptional repression ativity and is enhanced by HDAC4.
  • 細胞内局在Nucleus.
  • Information by UniProt
  • 参照データベース
  • 別名
    • Hic 1 antibody
    • Hic-1 antibody
    • Hic1 antibody
    • HIC1_HUMAN antibody
    • Hypermethylated in cancer 1 antibody
    • Hypermethylated in cancer 1 protein antibody
    • ZBTB29 antibody
    • Zinc finger and BTB domain-containing protein 29 antibody
    • ZNF901 antibody
    see all

Anti-HIC1 antibody 画像

  • Anti-HIC1 antibody (ab116557) at 1/100 dilution + NCI-H292 cell lysate at 35 µg

    Predicted band size : 77 kDa

Anti-HIC1 antibody (ab116557) 使用論文

ab116557 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab116557.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"