製品の概要

  • 製品名Anti-HHV8 ORF62 antibody
  • 製品の詳細
    Sheep polyclonal to HHV8 ORF62
  • アプリケーション適用あり: WBmore details
  • 免疫原

    Fusion protein that contains at its amino terminus the maltose binding protein (mal 62) and at its carboxy terminus the protein encoded by the Open reading frame 62 (ORF 62). ORF 62 interacts with the minor capsid protein of HHV8 and mediates its translocation to the nucleus where the assembly of the HHV8 capsid components take place.

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • バッファーPreservative: 0.08% Sodium Azide
    Constituents: PBS
  • Concentration information loading...
  • 精製度Protein G purified
  • 特記事項(精製)This antibody is provided as a 0.2µm sterile filtered solution.
  • ポリ/モノポリクローナル
  • アイソタイプIgG
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab16159 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/500.

ターゲット情報

  • 関連性Kaposi's sarcoma-associated herpesvirus (KSHV) belongs to the gamma-(2)-herpesvirus subfamily and has been closely linked to the Kaposi's sarcoma, primary effusion lymphoma (PEL) and multicentric Castleman's disease. The genome of KSHV is 165-170 kb and contains at least 88 open reading frames. At least five major proteins are likely to be involved in the assembly of the HHV-8 capsid, including a protease (encoded by ORF17), the major capsid protein (encoded by ORF25), and three other smaller capsid proteins (encoded by ORF62, ORF26, and ORF65). Previous structural studies have shown that the HSV-1 triplex is a monomer of VP19c and a dimer of VP23 and that the HCMV triplex is similarly composed of a monomer and a dimer. By analogy, the KSHV triplexes are likely also composed of a monomer of the ORF62 protein and a dimer of the ORF26 protein, which are the respective homologs of VP19c and VP23.
  • 別名
    • HHV8 antibody
    • Human herpes virus 8 antibody
    • Kaposi's sarcoma associated herpesvirus antibody
    • KSHV antibody
    • ORF62 antibody
    see all

Anti-HHV8 ORF62 antibody (ab16159) 使用論文

ab16159 has not yet been referenced specifically in any publications.

Product Wall

Thank you for your telephone enquiry yesterday afternoon. As requested, here is a list of all our antibodies for detection of HHV8 virus. I can recommend to review the online datasheets for further information. ab4103 Rat monoclonal Anti...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"