製品の概要

  • 製品名Anti-HHV8 antibody [LN35]
  • 製品の詳細
    Rat monoclonal [LN35] to HHV8
  • 特異性HHV 8 is the likely etiological agent of Kaposi’s sarcoma (KS). HHV 8 encodes a latent nuclear antigen (LNA), which is the product of the viral gene orf 73. LNA is capable of forming a complex with retinoblastoma susceptibility gene product, which may be related to its oncogenic activity.
  • アプリケーション適用あり: ICC/IF, IHC-P, IHC-Frmore details
  • 種交差性
    Human Herpes virus 8
  • 免疫原

    Recombinant protein corresponding to the latent nuclear antigen 1 molecule of HHV 8.

  • エピトープLocated within the ORF-73 region.
  • ポジティブ・コントロール
    • Kaposi’s sarcoma.

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • バッファーPreservative: 0.05% Sodium Azide
    Constituents: 1% BSA, Tissue culture supernatant
  • Concentration information loading...
  • 精製度IgG fraction
  • ポリ/モノモノクローナル
  • クローン名LN35
  • アイソタイプIgG2c
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab4103 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
ICC/IF Use at an assay dependent concentration. PubMed: 24250827
IHC-P 1/25 - 1/50. Perform heat mediated antigen retrieval before commencing with IHC staining protocol. ABC method.
IHC-Fr 1/25 - 1/50. ABC method.

ターゲット情報

  • 関連性HHV8 has been found to be associated with three different diseases observed in AIDS patients; kaposi's sarcoma, primary effusion lymphoma (which is a rare type of non-Hodgkin lymphoma affecting the body cavities) and multicentric Castleman's disease. To date there is much evidence to support a direct role for HHV8 in kaposi's sarcoma.
  • 別名
    • HHV 8 antibody
    • Human Herpes Virus 8 antibody
    • Human herpesvirus 8 antibody
    • Kaposi's sarcoma associated herpes virus antibody
    • KSHV antibody
    see all

Anti-HHV8 antibody [LN35] 画像

  • Cultured cells infected with HHV8, stained with HHV8 using ABC and DAB chromogen.

Anti-HHV8 antibody [LN35] (ab4103) 使用論文

This product has been referenced in:
  • El Hajj H  et al. Combination of arsenic and interferon-a inhibits expression of KSHV latent transcripts and synergistically improves survival of mice with primary effusion lymphomas. PLoS One 8:e79474 (2013). ICC/IF . Read more (PubMed: 24250827) »
  • Loddenkemper C  et al. [The morphologic variants of KSHV/HHV 8-associated lymphoproliferations.] Pathologe : (2006). Read more (PubMed: 17160657) »

See all 2 Publications for this product

Product Wall


The specific epitope of ab4103 is near the C terminus of the ORF-73 region within HHV8. Below is more information about specific recombinant proteins that this antibody recognizes.

GST-C14, GST-C17, GST-C7, and TH-C14;

GST-C14 co...

Read More

Thank you for contacting us.

We do not have clone 13B10 in catalogue like the Leica microsystem. We however have antibody that is specific to HHV8- latent nuclear antigen that can quoted to customer;

http://www.abcam.com/hhv8-antibody...

Read More



The laboratory responded that the epitope for ab4103 is near the C terminus of ORF 73 within HHV8.

Thank you for your telephone enquiry yesterday afternoon. As requested, here is a list of all our antibodies for detection of HHV8 virus. I can recommend to review the online datasheets for further information. ab4103 Rat monoclonal Anti...

Read More

Thank you for your enquiry and your patience in awaiting a response. HHV8 is human herpes virus and was tested only on human infected tissue. It was not tested for any other virus infected animal tissues. If you have any further questions then please d...

Read More

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"