製品の概要

製品の特性

  • 製品の状態
    Liquid
  • 保存方法
    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • バッファー
    Preservative: 0.1% Sodium Azide
    Constituents: Tris citrate/phosphate, pH 7-8
  • Concentration information loading...
  • 精製度
    Immunogen affinity purified
  • ポリ/モノ
    ポリクローナル
  • アイソタイプ
    IgG
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab46528 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 2 µg/ml. Predicted molecular weight: 32 kDa.
ELISA Use at an assay dependent dilution.

ターゲット情報

  • 機能
    Transcriptional regulator which functions as a general RNA polymerase II transcription inhibitor. In cooperation with 7SK snRNA sequesters P-TEFb in a large inactive 7SK snRNP complex preventing RNA polymerase II phosphorylation and subsequent transcriptional elongation.
  • 組織特異性
    Ubiquitously expressed with higher expression in testis. HEXIM1 and HEXIM2 are differentially expressed.
  • 配列類似性
    Belongs to the HEXIM family.
  • ドメイン
    The coiled-coil domain mediates oligomerization.
  • 細胞内局在
    Nucleus.
  • Information by UniProt
  • 参照データベース
  • 別名
    • Hexamethylene bis-acetamide-inducible protein 2 antibody
    • Hexamthylene bis-acetamide inducible 2 antibody
    • HEXI2_HUMAN antibody
    • hexim 2 antibody
    • HEXIM2 antibody
    • L3 antibody
    • Protein HEXIM2 antibody
    see all

画像

  • All lanes : Anti-HEXIM2 antibody (ab46528)

    Lane 1 : U373 cell lysate
    Lane 2 : HeLa cell lysate
    Lane 3 : 293T cell lysate
    Lane 4 : SK-Hep-1 cell lysate
    Lane 5 : IMR-90 cell lysate
    Lane 6 : TK6 cell lysate
    Lane 7 : CaCo-2 cell lysate


    Predicted band size : 32 kDa
    Observed band size : 32 kDa

プロトコール

参考文献

ab46528 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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