製品の概要

  • 製品名
  • 製品の詳細
    Rabbit polyclonal to HES7
  • アプリケーション
    適用あり: WBmore details
  • 種交差性
    交差種: Mouse, Human
  • 免疫原

    Synthetic peptide conjugated to KLH, corresponding to a region within N terminal amino acids 33-63 of Human HES7.

  • ポジティブ・コントロール
    • Mouse heart tissue lysate

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab102937 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/100 - 1/500. Predicted molecular weight: 25 kDa.

ターゲット情報

  • 機能
    Transcriptional repressor. Represses transcription from both N box- and E box-containing promoters. May with HES1, cooperatively regulate somite formation in the presomitic mesoderm (PSM). May function as a segmentation clock, which is essential for coordinated somite segmentation.
  • 関連疾患
    Defects in HES7 are the cause of spondylocostal dysostosis type 4 (SCDO4) [MIM:613686]. A rare condition of variable severity characterized by vertebral and costal anomalies. The main feature include dwarfism, vertebral fusion, hemivertebrae, posterior rib fusion, reduced rib number, and other rib malformations.
  • 配列類似性
    Contains 1 basic helix-loop-helix (bHLH) domain.
    Contains 1 Orange domain.
  • ドメイン
    Has a particular type of basic domain which includes a helix-interrupting proline.
    The C-terminal WRPW motif is a transcriptional repression motif which is necessary for interaction with Groucho/TLE family members, transcriptional corepressors recruited to specific target DNA by Hairy-related proteins.
  • 細胞内局在
    Nucleus.
  • Information by UniProt
  • 参照データベース
  • 別名
    • bHLH factor Hes7 antibody
    • bHLHb37 antibody
    • Class B basic helix loop helix protein 37 antibody
    • Class B basic helix-loop-helix protein 37 antibody
    • Hairy and enhancer of split 7 antibody
    • hes family bHLH transcription factor 7 antibody
    • Hes7 antibody
    • HES7_HUMAN antibody
    • hHes7 antibody
    • SCDO4 antibody
    • Transcription factor HES 7 antibody
    • Transcription factor HES-7 antibody
    see all

画像

  • Anti-HES7 antibody (ab102937) at 1/100 dilution + Mouse heart tissue lysate at 35 µg

    Predicted band size : 25 kDa

プロトコール

参考文献

ab102937 has not yet been referenced specifically in any publications.

レビューと Q&A

Thank you for your inquiry.

The exact immunogen sequences for these two antibodies are proprietary information. All the information I can provide is the region as it is stated on the datasheets:

ab26062: The immunogen is within ther...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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