製品の概要

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • バッファーPreservative: None
    PBS, pH 7.2
  • Concentration information loading...
  • 精製度Protein G purified
  • ポリ/モノモノクローナル
  • アイソタイプIgG2a
  • 軽鎖の種類kappa
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab57396 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB
  • 追加情報WB: Use at a concentration of 1-5 µg/ml.

    This antibody has only been tested in WB against the recombinant fragment used as immunogen. We have no data on the detection of endogenous protein.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 機能Transcriptional repressor of genes that require a bHLH protein for their transcription.
    • 組織特異性Expressed in placenta, pancreatic cancer, colon cancer with RER, cervical cancer, and in head and neck tumors.
    • 配列類似性Contains 1 bHLH (basic helix-loop-helix) domain.
      Contains 1 Orange domain.
    • ドメインHas a particular type of basic domain (presence of a helix-interrupting proline) that binds to the N-box (CACNAG), rather than the canonical E-box (CANNTG).
      The C-terminal WRPW motif is a transcriptional repression domain necessary for the interaction with Groucho/TLE family members, transcriptional corepressors recruited to specific target DNA by Hairy-related proteins.
    • 細胞内局在Nucleus.
    • Information by UniProt
    • 参照データベース
    • 別名
      • antibody
      • bHLHb40 antibody
      • Class B basic helix loop helix protein 40 antibody
      • Class B basic helix-loop-helix protein 40 antibody
      • Hairy and enhancer of split 2 (Drosophila) antibody
      • Hairy and enhancer of split 2 antibody
      • Hes2 antibody
      • HES2_HUMAN antibody
      • Transcription factor HES 2 antibody
      • Transcription factor HES-2 antibody
      see all

    Anti-HES2 antibody 画像

    • Western blot against tagged recombinant protein immunogen using ab57396 HES2 antibody at 1ug/ml. Predicted band size of immunogen is 34 kDa

    Anti-HES2 antibody (ab57396) 使用論文

    ab57396 has not yet been referenced specifically in any publications.

    Product Wall

    There are currently no Abreviews or Questions for ab57396.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"