保存方法 Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
バッファー Preservative: None
PBS, pH 7.2
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精製度 Protein G purified
Abpromise guarantee covers the use of
in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
追加情報 WB: Use at a concentration of 1-5 µg/ml. This antibody has only been tested in WB against the recombinant fragment used as immunogen. We have no data on the detection of endogenous protein. Not yet tested in other applications. Optimal dilutions/concentrations should be determined by the end user.
機能 Transcriptional repressor of genes that require a bHLH protein for their transcription.
組織特異性 Expressed in placenta, pancreatic cancer, colon cancer with RER, cervical cancer, and in head and neck tumors.
配列類似性 Contains 1 bHLH (basic helix-loop-helix) domain. Contains 1 Orange domain.
ドメイン Has a particular type of basic domain (presence of a helix-interrupting proline) that binds to the N-box (CACNAG), rather than the canonical E-box (CANNTG). The C-terminal WRPW motif is a transcriptional repression domain necessary for the interaction with Groucho/TLE family members, transcriptional corepressors recruited to specific target DNA by Hairy-related proteins.
Information by UniProt
Class B basic helix loop helix protein 40 antibody
Anti-HES2 antibody (ab57396) 使用論文
has not yet been referenced specifically in any publications.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"