製品の概要

  • 製品名Anti-Hepatitis C virus NS5B antibody
  • 製品の詳細
    Rabbit polyclonal to Hepatitis C virus NS5B
  • アプリケーション適用あり: WB, IP, ELISAmore details
  • 種交差性
    交差種: Hepatitis C Virus
  • 免疫原

    Recombinant protein NS5B (part of the NAS5AB recombinant antigen) from Hepatitis C virus with C-terminal truncation of 21 amino acid residues.

  • ポジティブ・コントロール
    • Hepatitis C Virus NS5B expressed in Huh7 cells

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab65410 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/1000. Predicted molecular weight: 65 kDa.
IP Use at an assay dependent dilution.
ELISA Use at an assay dependent dilution.

ターゲット情報

  • 関連性HCV is a positive, single-stranded RNA virus in the Flaviviridae family. The genome is approximately 10,000 nucleotides and encodes a single polyprotein of about 3,000 amino acids. The polyprotein is processed by host cell and viral proteases into three major structural proteins, and several non-structural proteins necessary for viral replication, of which NS5B is one. NS5B RNA-dependant RNA polymerase is responsible for replication of the hepatitis C viral genome, and is currently a principal target for chemotherapeutic inhibition of HCV replication. Hepatitis C virus (HCV) can cause chronic hepatitis, cirrhosis and hepatocellular carcinoma. At present there is no vaccine effective against HCV. Host membrane insertion occurs after processing by the NS3 protease.
  • 参照データベース
    • 別名
      • HCV NS5B antibody
      • Hepatitis C virus NS5B antibody
      • p68 antibody
      • RNA dependent RNA polymerase antibody
      • RNA directed RNA polymerase antibody
      see all

    Anti-Hepatitis C virus NS5B antibody (ab65410) 使用論文

    This product has been referenced in:
    • Li Q  et al. Hepatitis C virus infection activates an innate pathway involving IKK-a in lipogenesis and viral assembly. Nat Med 19:722-9 (2013). Hepatitis C Virus . Read more (PubMed: 23708292) »

    See 1 Publication for this product

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