Anti-Hepatitis C Virus NS5a 抗体 [H26] (ab13833)

製品の概要

  • 製品名Anti-Hepatitis C Virus NS5a antibody [H26]
    Hepatitis C Virus NS5a 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal [H26] to Hepatitis C Virus NS5a
  • 特異性Hepatitis C Virus antigen NS5a. This antibody works with the HCV genotypes 1a, 1b, 3 and 4, but not with genotype 2a.
  • アプリケーション適用あり: ELISA, WB, ICC/IFmore details
  • 免疫原

    Recombinant full length protein (E. coli).

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • バッファーPreservative: 0.1% Sodium Azide
    Constituents: PBS, pH 7.4
  • Concentration information loading...
  • 精製度Protein G purified
  • ポリ/モノモノクローナル
  • クローン名H26
  • アイソタイプIgG1
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab13833 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
ELISA Use at an assay dependent dilution.
WB 1/1000.
ICC/IF 1/50.

ターゲット情報

  • 関連性HCV is classified into the genus Hepacivirus of the family Flaviviridae. Like all the members of the family, HCV is an enveloped, single-stranded, positive-sense RNA virus. Its genome (about 9600 nt) is flanked at both termini by conserved, highly structured non-translated regions (NTRs) and encodes a polyprotein precursor (about 3000 aa), which is proteolytically processed by host and viral proteases to produce the structural (core, E1, E2 and p7) and non-structural (NS2, NS3, NS4A, NS4B, NS5A and NS5B) proteins of the virus. Recently, an additional protein has been identified, whose function remains unknown. NS5A is a ~56 kDa pleiotropic protein with key roles in both viral RNA replication and modulation of the physiology of the host cell. It's exact role is not currently known (2008).
  • 別名
    • HCV antibody
    • HCV Non-structural protein 5A antibody
    • Non-structural protein 5A antibody
    • NS5A antibody
    • p56 antibody
    see all

Anti-Hepatitis C Virus NS5a antibody [H26] 画像

  • Image from Scheel TK et al., PLoS Pathog. 2012 May;8(5):e1002696. Epub 2012 May 24.; Fig 6.; doi:10.1371/journal.ppat.1002696; May 24, 2012, PLoS Pathog 8(5): e1002696.

Anti-Hepatitis C Virus NS5a antibody [H26] (ab13833) 使用論文

This product has been referenced in:
  • Meistermann H  et al. A novel immuno-competitive capture mass spectrometry strategy for protein-protein interaction profiling reveals that LATS kinases regulate HCV replication through NS5A phosphorylation. Mol Cell Proteomics 13:3040-8 (2014). Read more (PubMed: 25044019) »
  • Scheel TK  et al. Analysis of functional differences between hepatitis C virus NS5A of genotypes 1-7 in infectious cell culture systems. PLoS Pathog 8:e1002696 (2012). WB ; Hepatitis C Virus . Read more (PubMed: 22654662) »

See all 2 Publications for this product

Product Wall

Thank you for your message.

Reviewing the recommended storage details for these antibodies, I can suggest they should not be significantly affected by short term storage for a week or two at +4oC. However, I would recommend to aliquot and fr...

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Thank you for your enquiry. I can confirm that the exact epitope is not know, but it has been mapped between amino acid positions 2200 and 2250. I hope this will be helpful to you. If you have any further questions, please do not hesitate to cont...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"